Toxicology

University of California, Berkeley

This is an archived copy of the 2014-15 guide. To access the most recent version of the guide, please visit http://guide.berkeley.edu/.

About the Program

Minor

The Department of Nutritional Science and Toxicology (NST) offers a minor in Toxicology. The course work for the minor addresses topics in the basic principles of toxicology and molecular toxicology as well as computational toxicology, pharmacology, and pesticide chemistry. The minor works best for students already pursuing a bioscience degree as a background in chemistry, organic chemistry, biology, and biochemistry is necessary to be prepared to do upper division work in this field.

Currently, there is no major program in Toxicology.

Declaring the Minor

For information regarding how to declare the minor, please contact the Department.

Other Major and Minor Offered by the Department of Nutritional Sciences and Toxicology

Nutritional Science (Major and Minor)

Visit Department Website

Minor Requirements

Students who have a strong interest in an area of study outside their major often decide to complete a minor program. These programs have set requirements and are noted officially on the transcript in the memoranda section, but they are not noted on diplomas.

General Guidelines

  1. All courses taken to fulfill the minor requirements below must be taken for graded credit.

  2. A minimum grade point average (GPA) of 2.0 is required for courses used to fulfill the minor requirements.

  3. No more than one upper-division course may be used to simultaneously fulfill requirements for a student's major and minor programs.

At least one of the five upper-division courses below must be taken during the academic year (i.e., not all courses may be Summer Session courses).

No substitutions to the courses listed below will be permitted.

Lower-division Prerequisites

CHEM 1AGeneral Chemistry3
CHEM 3AChemical Structure and Reactivity3
CHEM 3BChemical Structure and Reactivity3
BIOLOGY 1AGeneral Biology Lecture3

Minor Requirements 

NUSCTX 11Introduction to Toxicology3
NUSCTX 110Toxicology4
NUSCTX C114/ESPM C148Pesticide Chemistry and Toxicology3
NUSCTX 115Principles of Drug Action2
Select at least one elective from the following:
Nutrient Function and Metabolism
Human Food Practices
Introduction and Application of Food Science
Computational Toxicology
Human Diet
Metabolic Bases of Human Health and Diseases
Medical Nutrition Therapy
Nutrition in the Community
Introduction to Research in Nutritional Sciences
Introduction to Research in Toxicology
Honors Research
Supervised Independent Study and Research

Courses

Toxicology

NUSCTX 10 Introduction to Human Nutrition 3 Units

This course provides an overview of digestion and metabolism of nutrients. Foods are discussed as a source of nutrients, and the evidence is reviewed as to the effects of nutrition on health. The emphasis of the course is on issues of current interest and on worldwide problems of food and nutrition. Students are required to record their own diet, calculate its composition, and evaluate its nutrient content in light of their particular needs.

NUSCTX 11 Introduction to Toxicology 3 Units

Discussion of principles for the evaluation of toxic hazard of natural and man-made substances present in the environment, the workplace, food, drink, and drugs. The bases for species selectivity, individual variations in sensitivity and resistance, and the combined effects of toxic agents will be addressed. Issues related to the impact of toxic agents in modern society will be emphasized.

NUSCTX 24 Freshman Seminar 1 Unit

The Freshman Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Freshman seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

NUSCTX 98 Directed Group Study 1 - 3 Units

Study of special topics in nutritional sciences that are not covered in depth in regular courses.

NUSCTX 103 Nutrient Function and Metabolism 3 Units

Delivery of nutrients from foods to mammalian cells; major metabolic pathways; function of nutrients in energy metabolism, nitrogen and lipid metabolism, structural tissues and regulation; essentiality, activation, storage, excretion, and toxicity of nutrients.

NUSCTX 104 Human Food Practices 2 Units

Historical, geo-ecological, biological, cultural, socio-economic, political and personal determinants of human diets. Community food and nutrition problems and programs. Food safety and consumer protection. Contributes to the pursuit of multidisciplinary degrees in nutrition policy and planning.

NUSCTX 108A Introduction and Application of Food Science 3 Units

Evaluation of the chemical, physical, functional, and nutritional properities of foods. Emphasis on how these properties, and prepration, processing, and storage, influence quality characteristics of food products.

NUSCTX 108B Application of Food Science Laboratory 1 Unit

Experimental evaluation of the chemical, physical, functional, and nutritional properties of foods, and the changes occuring during preparation that affect quality characteristics of food products.

NUSCTX 110 Toxicology 4 Units

A comprehensive survey of the principles of modern toxicology and their applications in evaluating the safety of foods, additives and environmental contaminates. Mechanisms of metabolic activation, detoxification, gene regulation, and selective toxicity are emphasized.

NUSCTX C114 Pesticide Chemistry and Toxicology 3 Units

Chemical composition of pesticides and related compounds, their mode of action, resistance mechanisms, and methods of evaluating their safety and activity.

NUSCTX 115 Principles of Drug Action 2 Units

Basic principles and quantitative aspects of drug action and risk/benefit as applied to the discovery, design, and development of human therapeutics. The course will highlight the importance of integrating pharmacology, toxicology, and pharmacokinetics to create effective and safe treatments for human disease. Special emphasis will be placed on pharmacogenomics and variation in individual response.

NUSCTX 121 Computational Toxicology 3 Units

Introducing the use of bioinformatics tools useful in linking the molecular structure of chemicals to the toxicity they induce in biological systems. Discussions on the highly interactive process of collecting, organizing, and assimilating chemistry and toxicology information - and the use of computer programs to visualize, browse, and interpret this information to discover chemical structure-toxicity correlations. The importance of these concepts in drug discovery and development and food safety will be emphasized.

NUSCTX 135 Food Systems Organization and Management 4 Units

Principles of organization and management applied to institutional food service systems: production and delivery systems, management of resources, quality assurance, equipment, layout, marketing, personnel management, fiscal management. Laboratory experiences, projects and field work in institutional situations.

NUSCTX 145 Nutrition Education and Counseling 2 Units

This course will focus on communicating nutrition messages through nutrition education and nutrition counseling. Students will develop and implement theory-based nutrition education interventions and conduct mock counseling sessions for various populations and conditions. Strategies for effective nutrition instruction, counseling, and behavior change will be discussed.

NUSCTX C159 Human Diet 4 Units

Since we eat every day, wouldn't it be useful to learn more about human dietary practices? A broad overview of the complex interrelationship between humans and their foods. Topics include the human dietary niche, biological variation related to diet, diet and disease, domestication of staple crops, food processing techniques and development of regional cuisines, modern diets and their problems, food taboos, human attitudes toward foods, and dietary politics.

NUSCTX 160 Metabolic Bases of Human Health and Diseases 4 Units

The physiological bases of human nutrient homeostasis and common disorders resulting from over and under nutrition will be discussed with a specific focus on macronutrients. Topics related to nutrient deficiency and excess will include adaptation to starvation and the effects of caloric restriction on life-span, obesity and its complications, lipoprotein metabolism and cardiovascular disease, as well as a detailed discussion of the causes, disease mechanisms, and treatment of diabetes mellitus.

NUSCTX 161A Medical Nutrition Therapy 4 Units

This lecture course addresses nutrition as a component of disease treatment. As we explore medical nutrition therapy, we will also study disease pathophysiology, diagnosis, and medical and pharmacological treatments. Methods of nutrition assessment and nutrient delivery in a medical setting will be covered.

NUSCTX 161B Medical Nutrition Therapy II 4 Units

This is the second course of a two part series that is a continuation of addressing nutrition as a component of disease treatment. The Nutrition Care Process will be applied and disease pathophysiology, diagnosis, medical and pharmacological treatments and nutritional therapies for prevention and treatment will be explored for various disease states.

NUSCTX 166 Nutrition in the Community 3 Units

This course addresses basic nutrition in the context of the community. It explores nutrition programs that serve various segments of the population and the relationships of these programs to nutrition policy at the local, national, and international levels. Community assessment is used as the basis for program planning, implementation, and evaluation. The specific needs of population groups (infants, children, women, and the elderly) are considered and questions of food security are investigated.

NUSCTX 170 Experimental Nutrition Laboratory 4 Units

Basic principles and techniques used in human and animal nutrition research. Students design, execute, and analyze experiments.

NUSCTX 171 Nutrition and Toxicology Laboratory 4 Units

Basic principles and techniques used in human and animal nutrition and toxicology research. Students design, execute, and analyze experiments.

NUSCTX 190 Introduction to Research in Nutritional Sciences 1 Unit

Students will be asked to prepare an oral and written report on a topic selected from the current research literature in nutritional sciences.

NUSCTX 192 Junior Seminar in Dietetics 1 Unit

This seminar course explores the professional roles and responsibilities of dietitians as well as career opportunities within the field. Current issues in the practice of dietetics will be discussed. Students will do research and present an oral report to the class. Each student will begin to develop his or her professional portfolio.

NUSCTX 193 Introduction to Research in Toxicology 1 Unit

Students will be asked to prepare an oral and written report on a topic selected from the current research literature in toxicology.

NUSCTX 194 Senior Seminar in Dietetics 2 Units

This course will cover the changes that are occurring in the field of dietetics. Students will explore revisions of the national nutritional standards and guidelines, issues related to complementary and alternative nutrition practices, the area of genomics as it is expected to affect practice, professional ethics in the changing health care environment, reimbursement for professional services, legislation related to the field of dietetics, and other emerging issues.

NUSCTX H196 Honors Research 4 Units

Supervised independent honors research specific to aspects of the Nutritional Science and Toxicology major, followed by an oral presentation, and a written report.

NUSCTX 197 Field Study in Food and Nutritional Sciences 1 - 3 Units

Supervised experience in off-campus organizations relevant to specific aspects of foods and nutritional sciences. Regular individual meetings with faculty sponsor and written reports required.

NUSCTX 198 Directed Group Study 1 - 3 Units

Study of special topics in food science or nutrition that are not covered in depth in regular courses.

NUSCTX 199 Supervised Independent Study and Research 1 - 4 Units

Upper division laboratory and independent research under the direction of a faculty supervisor. Written report required upon completion of the project.

Faculty

Professors

Gregory W. Aponte, Professor. Health and nutrition, nutritional science, neuropeptides, regulation of intestinal epithelial cell differentiation, proliferation, G-protein coupled receptors.
Research Profile

Marc Hellerstein, Professor. Plant biology, health and nutrition.
Research Profile

Joseph L Napoli, PhD, Professor. Cancer, metabolism, nervous system, nutritional biochemistry, fat-soluble vitamins, retinoids, retinoic acid, retinol, vitamin A.
Research Profile

Barry Shane, Professor. Plant biology, health and nutrition, nutritional sciences and toxicology.
Research Profile

Hei Sook Sul, Professor. Plant biology, health and nutrition, nutritional sciences & toxicology.
Research Profile

Christopher D. Vulpe, Professor. Genetics, genomics, ecotoxicology, gene expression, water quality, copper, iron, toxicology, susceptibility, environmental, ecotoxicogenomics.
Research Profile

Associate Professors

Andreas Stahl, PhD, Associate Professor.

Jen-Chywan (Wally) Wang, PhD, Associate Professor. Molecular physiology, molecular pharmacology, mechanisms of glucocorticoid receptor-regulated metabolism.
Research Profile

Assistant Professors

Danica Chen, PhD, Assistant Professor. Aging, stem cell, diseases of aging.
Research Profile

Daniel K Nomura, PhD, Assistant Professor.

James A. Olzmann, PhD, Assistant Professor.

Adjunct Faculty

Dale E. Johnson, Adjunct Faculty.

Ronald M Krauss, MD, Adjunct Faculty.

Dale Leitman, Adjunct Faculty.

Robert O. Ryan, PhD, Adjunct Faculty.

Contact Information

Department of Nutritional Sciences and Toxicology

119 Morgan Hall

Phone: 510-642-6490

Fax: 510-642-0535

Visit Department Website

Department Chair

Joseph Napoli, PhD

119, 150, or 208 Morgan Hall

Phone: 510-642-0809

jna@berkeley.edu

Student Services

Nikki Milbrath

115 Morgan Hall

Phone: 510-643-2863

nmilbrath@berkeley.edu

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