About the Program
Bachelor of Arts (BA)
The undergraduate major in Molecular and Cell Biology (MCB) encompasses the diversity of scientific interests of the Department's faculty. The Cell & Developmental Biology (CDB) emphasis focuses on investigating the dynamic mechanisms of fundamental cellular processes in both normal and aberrant physiological contexts such as disease and developmental disorders. The undergraduate tracks within this emphasis are ideal for students interested in the medical and health sciences as well as basic research and teaching careers.
The major program has 2 tracks: Track 1, Cell & Systems Biology, and Track 2, Medical Biology & Physiology.
Declaring the Major
MCB is not an impacted major. Therefore, the program will accept any interested student who meets the minimum course and GPA requirements and is realistically able to complete the major requirements during the student's remaining time at UC Berkeley.
In order to declare the MCB major, students must have completed or be enrolled in BIOLOGY 1A/BIOLOGY 1AL (C or better on first midterm) and CHEM 3B (past the early drop deadline), have at least a 2.0 overall GPA, a 2.0 GPA in the lower-division prerequisites for the major, and know which emphasis they will declare. (Note: Transfer students must have completed at least one semester at UC Berkeley and have received a 2.0 GPA in the courses that they have taken for the major). Intended MCB students are not required to have completed the Math or Physics requirement at the time of declaration (though the requirement must be met in order to graduate).
To start the major declaration process, students must: (1) fill out the MCB major declaration form online ; and (2) download and fill out the Petition to Declare a Major .
Students should bring the Petition to Declare a Major to the Undergraduate Advising Office (3060 Valley Life Sciences Building) no earlier than the next business day to discuss their academic plan. When signing in, students should inform the Intake Adviser that they declared online. S/he will hand them the printed course planning form to take to an academic adviser for planning their courses in the major. Please note that major declarations are limited during the first week of class and the first week of TeleBEARS Phase 1. Any restrictions will be advertised on the homepage and in the weekly email. Please plan accordingly.
Honors Program
The MCB honors program offers exceptional senior students recognition for outstanding academic achievement and excellence in research. To graduate with honors in the major, students must satisfy the following:
- Complete at least two credited semesters of research including four to eight units of MCELLBI H196A and/or MCELLBI H196B (Honors Research)
- Have a cumulative Berkeley grade point average (GPA) of at least 3.3 in all work completed at UC Berkeley
- Have at least a 3.5 GPA in the MCB major requirements or 3.5 GPA in MCB upper division courses
- Present their research in an approved forum, such as an MCB symposium, the Undergraduate Poster Session, or other scientific meeting
- Write an honors thesis approved by an MCB faculty sponsor
Additional information on the honors program is available in the Undergraduate Affairs Office and on the MCB website .
Minor Program
There is no minor program in Molecular and Cell Biology.
Other Molecular and Cell Biology Majors (Emphases)
Biochemistry & Molecular Biology
(BMB)
Genetics, Genomics, & Development
(GG & D)
Immunology & Pathogenesis
(IM & P)
Neurobiology
Major Requirements
In addition to the University, campus, and college requirements, listed on the College Requirements tab, students must fulfill the below requirements specific to their major program.
General Guidelines
- All courses taken to fulfill the major requirements below must be taken for graded credit, other than courses listed which are offered on a Pass/No Pass basis only. Other exceptions to this requirement are noted as applicable.
- No more than one upper-division course may be used to simultaneously fulfill requirements for a student's major and minor programs, with the exception of minors offered outside of the College of Letters and Science.
- A minimum grade point average (GPA) of 2.0 must be maintained in both upper- and lower-division courses used to fulfill the major requirements.
For information regarding residence requirements and unit requirements, please see the College Requirements tab.
Lower-division Requirements: All Tracks
MATH 10A | Methods of Mathematics: Calculus, Statistics, and Combinatorics | 4 |
MATH 10B | Methods of Mathematics: Calculus, Statistics, and Combinatorics | 4 |
CHEM 1A & 1AL | General Chemistry and General Chemistry Laboratory | 4 |
CHEM 3A | Chemical Structure and Reactivity | 2-3 |
or CHEM 3AL | Organic Chemistry Laboratory | |
CHEM 3B | Chemical Structure and Reactivity | 2-3 |
or CHEM 3BL | Organic Chemistry Laboratory | |
BIOLOGY 1A/1AL | General Biology Lecture | 3 |
BIOLOGY 1B | General Biology Lecture and Laboratory | 4 |
PHYSICS 8A | Introductory Physics 1 | 4 |
PHYSICS 8B | Introductory Physics 1 | 4 |
1 | PHYSICS 7A and PHYSICS 7B can be taken in place of PHYSICS 8A and PHYSICS 8B. |
Upper-division Requirements: Cell & Systems Biology Track
MCELLBI 102 | Survey of the Principles of Biochemistry and Molecular Biology | 4 |
MCELLBI 104 | Genetics, Genomics, and Cell Biology | 4 |
MCELLBI 130A | Cell and Systems Biology | 4 |
MCELLBI 133L | Physiology and Cell Biology Laboratory | 4 |
Two CDB Electives from List A (see below) |
Upper-division Requirements: Medical Biology and Physiology Track
MCELLBI 102 | Survey of the Principles of Biochemistry and Molecular Biology | 4 |
MCELLBI 104 | Genetics, Genomics, and Cell Biology | 4 |
MCELLBI 136 | Physiology | 4 |
MCELLBI 133L | Physiology and Cell Biology Laboratory | 4 |
Two CDB Electives from List B (see below) |
CDB Elective A List
MCELLBI C100A | Biophysical Chemistry: Physical Principles and the Molecules of Life | 4 |
MCELLBI C103 | Bacterial Pathogenesis | 3 |
MCELLBI C112 | General Microbiology | 4 |
MCELLBI C114 | Introduction to Comparative Virology | 4 |
MCELLBI C116 | Microbial Diversity | 3 |
MCELLBI 132 | Biology of Human Cancer | 4 |
MCELLBI C134 | Chromosome Biology/Cytogenetics | 3 |
MCELLBI 135A | Topics in Cell and Developmental Biology: Molecular Endocrinology | 3 |
MCELLBI 136 | Physiology | 4 |
MCELLBI 137 | Computer Simulation in Biology | 3 |
MCELLBI 141 | Developmental Biology | 4 |
MCELLBI 143 | Evolution of Genomes, Cells, and Development | 3 |
MCELLBI C145 | Course Not Available | 4 |
MCELLBI C146 | Course Not Available | 4 |
MCELLBI C148 | Microbial Genomics and Genetics | 4 |
MCELLBI 150 | Molecular Immunology | 4 |
MCELLBI C160 | Course Not Available | |
MCELLBI 163 | Mammalian Neuroanatomy | 4 |
MCELLBI 165 | Neurobiology of Disease | 3 |
MCELLBI 166 | Biophysical Neurobiology | 3 |
MCELLBI 167 | Course Not Available |
CDB Elective B List
Any course from Elective A List above | ||
INTEGBI 103LF | Invertebrate Zoology with Laboratory | 5 |
INTEGBI 104LF | Natural History of the Vertebrates with Laboratory | 5 |
INTEGBI 117 & 117LF | Medical Ethnobotany and Medical Ethnobotany Laboratory | 4 |
INTEGBI 123AL | Exercise Physiology with Laboratory | 5 |
INTEGBI 131 | General Human Anatomy | 3 |
INTEGBI 137 | Human Endocrinology | 4 |
INTEGBI 140 | Biology of Human Reproduction | 4 |
INTEGBI C143A | Biological Clocks: Physiology and Behavior | 3 |
INTEGBI C143B | Hormones and Behavior | 3 |
INTEGBI 148 | Comparative Animal Physiology | 3 |
NUSCTX 103 | Nutrient Function and Metabolism | 3 |
NUSCTX 108A | Introduction and Application of Food Science | 3 |
NUSCTX 110 | Toxicology | 4 |
NUSCTX 150 | Course Not Available | |
NUSCTX 160 | Metabolic Bases of Human Health and Diseases | 4 |
NUSCTX 161A | Medical Nutrition Therapy | 4 |
PLANTBI 135 | Physiology and Biochemistry of Plants | 3 |
PLANTBI 150 | Plant Cell Biology | 3 |
PLANTBI 160 | Plant Molecular Genetics | 3 |
PLANTBI 170 | Modern Applications of Plant Biotechnology | 2 |
PSYCH 110 | Introduction to Biological Psychology | 3 |
PSYCH C113 | Biological Clocks: Physiology and Behavior | 3 |
PSYCH C116 | Hormones and Behavior | 3 |
PB HLTH 141 | Introduction to Biostatistics | 5 |
PB HLTH 142 | Introduction to Probability and Statistics in Biology and Public Health | 4 |
PB HLTH 150A | Introduction to Epidemiology and Human Disease | 4 |
PB HLTH 150B | Introduction to Environmental Health Sciences | 3 |
PB HLTH 162A | Public Health Microbiology | 3 |
PB HLTH 172 | Course Not Available | 3 |
STAT 131A | Introduction to Probability and Statistics for Life Scientists | 4 |
College Requirements
Undergraduate students in the College of Letters and Science must fulfill the following requirements in addition to those required by their major program.
For detailed lists of courses that fulfill college requirements, please see the College of Letters and Sciences page in this bulletin.
Entry Level Writing
All students who will enter the University of California as freshmen must demonstrate their command of the English language by fulfilling the Entry Level Writing Requirement. Fulfillment of this requirement is also a prerequisite to enrollment in all reading and composition courses at UC Berkeley.
American History and American Institutions
The American History and Institutions requirements are based on the principle that a U.S. resident graduated from an American university should have an understanding of the history and governmental institutions of the United States.
American Cultures
American Cultures is the one requirement that all undergraduate students at Cal need to take and pass in order to graduate. The requirement offers an exciting intellectual environment centered on the study of race, ethnicity and culture of the United States. AC courses offer students opportunities to be part of research-led, highly accomplished teaching environments, grappling with the complexity of American Culture.
Quantitative Reasoning
The Quantitative Reasoning requirement is designed to ensure that students graduate with basic understanding and competency in math, statistics, or computer science. The requirement may be satisfied by exam or by taking an approved course.
Foreign Language
The Foreign Language requirement may be satisfied by demonstrating proficiency in reading comprehension, writing, and conversation in a foreign language equivalent to the second semester college level, either by passing an exam or by completing approved course work.
Reading and Composition
In order to provide a solid foundation in reading, writing and critical thinking the College requires two semesters of lower division work in composition. Students must complete a first-level reading and composition course by the end of their second semester and a second-level course by the end of their fourth semester.
Breadth Requirements
The undergraduate breadth requirements provide Berkeley students with a rich and varied educational experience outside of their major program. As the foundation of a liberal arts education, breadth courses give students a view into the intellectual life of the University while introducing them to a multitude of perspectives and approaches to research and scholarship. Engaging students in new disciplines and with peers from other majors, the breadth experience strengthens interdisciplinary connections and context that prepares Berkeley graduates to understand and solve the complex issues of their day.
Unit Requirements
-
120 total units, including at least 60 L&S units
-
Of the 120 units, 36 must be upper division units
- Of the 36 upper division units, 6 must be taken in courses offered outside your major department
Residence Requirements
For units to be considered in "residence," you must be registered in courses on the Berkeley campus as a student in the College of Letters and Science. Most students automatically fulfill the residence requirement by attending classes here for four years. In general, there is no need to be concerned about this requirement, unless you go abroad for a semester or year or want to take courses at another institution or through University Extension during your senior year. In these cases, you should make an appointment to see an adviser to determine how you can meet the Senior Residence Requirement.
Note: Courses taken through UC Extension do not count toward residence.
Senior Residence Requirement
After you become a senior (with 90 semester units earned toward your B.A. degree), you must complete at least 24 of the remaining 30 units in residence in at least two semesters. To count as residence, a semester must consist of at least 6 passed units. Intercampus Visitor, EAP, and UC Berkeley-Washington Program (UCDC) units are excluded.
You may use a Berkeley summer session to satisfy one semester of the Senior Residence Requirement, provided that you successfully complete 6 units of course work in the Summer Session and that you have been enrolled previously in the College.
Modified Senior Residence Requirement
Participants in the UC Education Abroad Program (EAP) or the UC Berkeley-Washington Program (UCDC) may meet a Modified Senior Residence Requirement by completing 24 (excluding EAP) of their final 60 semester units in residence. At least 12 of these 24 units must be completed after you have completed 90 units.
Upper Division Residence Requirement
You must complete in residence a minimum of 18 units of upper division courses (excluding EAP units), 12 of which must satisfy the requirements for your major.
Sample Plan of Study
The sample plans below show a four-year plan for completing the major, taking classes only during Fall and Spring semesters. All of the lower-division classes are offered during the Summer as well. Please consult the sample plan appropriate to your track.
Please note that the sample plans below include only courses required for your major. For more detailed information regarding other requirements, including unit minimums per semester, Letters and Science Breadth Requirements, Reading and Composition (R & C), and the American Cultures (AC) requirements, please see the College Requirements tab.
Track 1: Cell & Systems Biology, Freshman Admits
Track 2: Medical Biology & Physiology, Freshmen Admits
Freshman | |||
---|---|---|---|
Fall | Units | Spring | Units |
MATH 10A | 4 | MATH 10B | 4 |
CHEM 1A & 1AL | 4 | BIOLOGY 1A & 1AL | 5 |
8 | 9 | ||
Sophomore | |||
Fall | Units | Spring | Units |
CHEM 3A & 3AL | 5 | CHEM 3B & 3BL | 5 |
BIOLOGY 1B | 4 | PHYSICS 8A | 4 |
9 | 9 | ||
Junior | |||
Fall | Units | Spring | Units |
MCELLBI 102 | 4 | MCB Core Course | |
PHYSICS 8B | 4 | MCB Lab | |
8 | 0 | ||
Senior | |||
Fall | Units | Spring | Units |
MCB Core Course | MCB Elective | ||
MCB Elective | |||
0 | 0 | ||
Total Units: 43 |
Track 1: Cell & Systems Biology, Fall Program for Freshmen Students
Track 2: Medical Biology & Physiology, Fall Program for Freshmen Students
Freshman | |||
---|---|---|---|
Fall | Units | Spring | Units |
MATH 1A | 4 | CHEM 1A & 1AL | 4 |
MATH 1B | 4 | ||
4 | 8 | ||
Sophomore | |||
Fall | Units | Spring | Units |
BIOLOGY 1A & 1AL | 5 | CHEM 3A & 3AL | 5 |
PHYSICS 8A | 4 | BIOLOGY 1B | 4 |
9 | 9 | ||
Junior | |||
Fall | Units | Spring | Units |
CHEM 3B & 3BL | 5 | MCELLBI 102 | 4 |
PHYSICS 8B | 4 | MCB Elective | |
9 | 4 | ||
Senior | |||
Fall | Units | Spring | Units |
MCB Core Course | MCB Lab | ||
MCB Elective | MCB Core Course | ||
0 | 0 | ||
Total Units: 43 |
Student Learning Goals
Mission
The Department of Molecular and Cell Biology (MCB) is a large department that is subdivided into five divisions: Biochemistry, Biophysics, and Structural Biology (BBS); Cell and Developmental Biology (CDB); Genetics, Genomics & Development (GGD); Immunology & Pathogenesis (IMMP); and Neurobiology (NEU). All MCB students complete the same lower division coursework to gain critical training in Biology, Mathematics, Chemistry, and Physics. All or most lower division coursework is completed before major declaration. Upon declaring the major, MCB students choose an emphasis, or specialization, which determines the upper division core courses they will take and elective choices from which they will choose. Students can choose among several areas of specialization; emphases are broadly defined along divisional lines and allow students to focus on a more defined topic within MCB. MCB students who elect to participate in independent research may choose from sponsoring research laboratories within any MCB division, or, upon approval, in laboratories outside the Department (other UCB departments, LBNL, CHORI, UCSF, biotechnology companies). The MCB major provides excellent preparation for many careers and post-baccalaureate training programs, including graduate programs and heath-related professional programs (e.g., medicine, dentistry, optometry, pharmacy), science writing, law school, biotechnology, teaching, and academic research.
Learning Goals for the Major
- Describe basic biological concepts and principles
- Appreciate the different levels of biological organization, from molecules to ecosystems
- Understand that biology has a chemical, physical, and mathematical basis
- Explain the importance of the scientific method to understanding natural phenomena
- Effectively communicate scientific data and ideas, both orally and in writing
- Critically evaluate data, develop a hypothesis, and design experiments to address an interesting and novel problem
- Demonstrate advanced knowledge in a specialized field of molecular and cell biology
Advising
MCB offers three types of undergraduate advising: staff advisers, faculty advisers, and peer advisers .
Staff Advisers
Staff academic advisors are trained to support students and assist them in successfully completing their MCB major. They are excellent resources for questions concerning administration and academics or finding out about other available services. Students should see a staff adviser for the following:
- Ask questions about major requirements
- Ask advice about schedule planning
- Declare the MCB major
- Consult about research opportunities, graduate and professional schools, career opportunities, scholarships, and internships
- Get their Adviser Code (AC) to access Tele-BEARS registration
- Get information and course control numbers (CCN's) for independent research
- Request general assistance, advice or information
- Find out about upcoming events and programs
Staff advisers are primarily available for drop-in advising, though limited appointments are available for more complex issues such as probation, academic difficulty, and re-admission. Students who would like to schedule an appointment should call 510-643-8895 during drop-in advising hours.
The general email address is mcbuao@berkeley.edu . This email is checked daily, Monday-Friday, so students will receive an answer to questions within one business day.
Advising Staff:
James Depealteau, 510-643-8895
Anwar Thomas, 510-643-8895
Faculty Advisers
Faculty advisers are MCB professors assigned to advise students about the MCB Department, its courses, research, and other academic issues. Students are assigned a faculty adviser when they declare an MCB major. Students should see their faculty advisers for the following:
- Receive guidance toward achieving academic and career goals
- Ask questions about the content of MCB courses
- Request exceptions to MCB major requirements and policies (obtain their signature on MCB Substitution Form)
- Ask questions about biological research and about the field of biology in general
- Ask for recommendations on which graduate schools to attend
- Get their signature on the Curriculum Planning Form, after speaking with a UAO staff advisor first
For a list of advisers and their office hours, please see the Department's website . Office hours listed are designated for drop-in advising unless otherwise noted. Faculty adviser office hours are effective from the first day of instruction until the final day of instruction for the fall and spring semesters. Faculty advisers are not available for office hours during winter or summer break. Students may refer to staff drop-in advising hours during summer sessions and non-instructional periods.
Peer Adviser Walk-in Services (PAWS)
Peer advisers are junior & senior MCB majors who volunteer their time to complement the UAO advising services by sharing their knowledge of and experience with lower-division requirements and upper-division classes, experience with student groups on campus, preparation for life beyond the BA, and use of various campus resources. To see the schedule and more information about who the peer advisers are and which courses they have taken, click here .
Academic Opportunities
Undergraduate Research
Under the guidance of an MCB faculty sponsor, undergraduates in the MCB major may have the opportunity to work in a laboratory to gain valuable experience in scientific research. Interested students must take the initiative to make such arrangements. Over 40% of MCB majors work in a lab to gain valuable experience in scientific research. To get started, students should talk with classmates, peer advisers, a staff undergraduate adviser, graduate student instructors (GSIs), and faculty about their interest in learning more about laboratory research. For more information on research, see How to Find a Lab Position .
Benefits of research:
- Science is a way to figure things out, so doing research will aid students in other aspects of their life. Students ask and answer open ended questions and link seemingly disconnected pieces of information to find results that were not predicted.
- Explore things at the cutting edge and that no one has explored before.
- Learn tenacity, problem solving, and learn to be critical about the details because things have to be reproducible.
- Solve mysteries and experience the excitement of discovery.
Students may receive academic credit for their work by enrolling in an independent study course: MCELLBI 99/MCELLBI 199 or MCELLBI H196A/MCELLBI H196B. Enrollment applications are due in the Undergraduate Advising Office by the fifth week of each semester.
Other Research Opportunities
For additional resources for information regarding research opportunities, please see the links below:
Undergraduate Research Apprentice Program (URAP)
Scholarship Connection
Summer research opportunities
Office of Research
Funding for Student Research
There are a variety of ways to support students' research. The Department recommends attending a workshop at the Office of Undergraduate Research or looking for funding opportunities on their website or the Scholarship Connection website .
Courses
Molecular and Cell Biology: Cell and Development Biology
MCELLBI 15 Current Topics in the Biological Sciences 2 Units
Students in this course will critically examine modern methods of biological investigations and their social implications. Relevant literature will be used to present basic biological concepts that address the cultural, technological and health aspects of current topics in the biological sciences. Designing and evaluating scientific questions will be stressed.
Rules & Requirements
Prerequisites: Suitable for freshmen who plan to major in a biological science
Repeat rules: Course may be repeated for credit as topic varies. Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Matsui
MCELLBI C31 Big Ideas in Cell Biology 3 Units
An introduction for students who do not intend to major in biology but who wish to satisfy their breadth requirement in Biological Sciences. Some major concepts of modern biology, ranging from the role of DNA and the way cells communicate, to interactions of cells and creatures with their environment, will be discussed without jargon and with attention to their relevance in contemporary life and culture.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Wilt
Also listed as: L & S C30X
MCELLBI 32 Introduction to Human Physiology 3 Units
A comprehensive introduction to human cell biology. The course will concentrate on basic mechanisms underlying human life processes, including cells and membranes; nerve and muscle function; cardiovascular, respiratory, renal, and gastrointestinal physiology; metabolism, endocrinology, and reproduction.
Rules & Requirements
Prerequisites: One year high school or college chemistry
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 6 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Machen, Ball
MCELLBI 32L Introduction to Human Physiology Laboratory 2 Units
Experiments and demonstrations are designed to amplify and reinforce information presented in 32. Exercises include investigations into the structure and function of muscle, nerve, cardiovascular, renal, respiratory, endocrine, and blood systems.
Rules & Requirements
Prerequisites: 32 or may be taken concurrently
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 3 hours of laboratory per week
Summer:
6 weeks - 2 hours of lecture and 8 hours of laboratory per week
8 weeks - 2 hours of lecture and 6 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Ball
MCELLBI 41 Genetics and Society 3 Units
Basic communication of inheritance; gene mapping; gene expression and genetic disease in animals and humans; social inheritance of genetics.
Rules & Requirements
Prerequisites: Primarily for students not specializing in biology
Credit Restrictions: Students will receive no credit after taking Biology 1A, Biology 1B, or Letters and Science 18.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Summer:
6 weeks - 7.5 hours of lecture per week
8 weeks - 6 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI C44 Biology for Voters 3 Units
This is a Discovery Course for non-Biology majors designed to introduce lower-division college students to biology through the lens of the contemporary problems facing people, the planet and the species of the planet. Modern genetic contributions will be presented on such issues as genetic engineering of plants and animals, the emergence of new pathogens, the role of genetic variation among individuals, and the extent to which DNA is and isn’t destiny. Each week will close with the presentation and discussion of a defining biological challenge facing the world.
Objectives & Outcomes
Student Learning Outcomes: The learning objectives will be, at one end, to understand what an experiment is, how is it controlled and what does one need to know about an experiment to be able to rely upon any conclusion. That is the fundamental issue in all science, and is frequently overlooked in many media accounts of science. A second objective is to learn enough of the language of biology to be able to ask the kind of informed questions that we would want all elected representatives to pay attention to. A third objective is for students to cultivate confidence that through non-specialized information sources they can become informed consumers of contemporary scientific thought, and to develop those habits of intellect to think about evidence in a scientific manner. A fourth objective is for students to enjoy the abundance of high quality books, articles and multimedia that will enable a lifetime of discovery outside the structure of a college course.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Rine, Urnov
Also listed as: L & S C30Y
MCELLBI 50 The Immune System and Disease 3 Units
Course will discuss how the immune system resolves, prevents, or causes disease. A general overview of the immune system will be covered in the first five weeks followed by five weeks discussing infectious diseases including anthrax, mad cow, herpes, malaria, tuberculosis, and HIV. In addition, other lectures will focus on current immunology topics including vaccines, autoimmunity, allergy, transplantation, and cancer.
Rules & Requirements
Prerequisites: High school chemistry or Chemistry 1A and high school biology or BIOLOGY 1A. BIOLOGY 1AL is not required
Credit Restrictions: Students will receive no credit for 50 after taking 102 or C100A/Chemistry C130.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Beatty
MCELLBI 55 Plagues and Pandemics 3 Units
Discussion of how infectious agents cause disease and impact society at large. We will examine historical and current examples of plagues and pandemics and consider the question of what we should do to ameliorate the impact of infectious disease in the future. The course is intended for non-majors and will begin by briefly providing necessary background in microbiology and immunology. The primary focus in each subsequent week, however, will be on discussing a particular infectious disease. The course will be broad in scope covering biological, historical, ethical and social implications of each disease.
Rules & Requirements
Credit Restrictions: Students will receive no credit for 55 after taking 100, C100A, 100B, 102, 103, C103, 150, Chemistry C130, Plant and Microbial Biology C103, and Public Health C102.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Beatty, Vance
MCELLBI C61 Brain, Mind, and Behavior 3 Units
Introduction to human brain mechanisms of sensation, movement, perception, thinking, learning, memory, and emotion in terms of anatomy, physiology, and chemistry of the nervous system in health and disease. Intended for students in the humanities and social sciences and others not majoring in the biological sciences.
Rules & Requirements
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology C61 after completing Molecular and Cell Biology 61, N61, W61, Psychology C61, Molecular and Cell Biology 104, C100A/Chemistry C130, Molecular and Cell Biology 110, 130A, 136, 160, C160/Neuroscience C160 or Integrative Biology 132. A deficient grade in Molecular and Cell Biology 61, N61, W61, or Psychology C61 may be removed by taking Molecular and Cell Biology C61/Psychology C61.<BR/>
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Presti
Also listed as: PSYCH C61
MCELLBI W61 Brain, Mind, and Behavior 3 Units
This course deals with the structure and function of the human nervous system, with an emphasis on how brain physiology and chemistry are related to human behavior. This is a comprehensive introduction to the exciting field of contemporary neuroscience for students of all backgrounds and interests, including those from the humanities and social sciences, as well as physical and biological sciences. The Final Examination will be administered in a proctored setting. See Schedule of Classes for meeting information. This course is web-based.
Rules & Requirements
Credit Restrictions: Students will receive no credit for W61 after taking 61, C61, N61, or Letters and Science C30W. A deficient grade in 61, C61, N61, or Letters and Science C30W may be removed by taking W61.
Hours & Format
Summer:
6 weeks - 7 hours of web-based lecture and 2.5 hours of web-based discussion per week
8 weeks - 5.5-6 hours of web-based lecture and 1.5 hours of web-based discussion per week
Online: This is an online course.
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Presti
Formerly known as: N61
MCELLBI C62 Drugs and the Brain 3 Units
The history, chemical nature, botanical origins, and effects on the human brain and behavior of drugs such as stimulants, depressants, psychedelics, analgesics, antidepressants, antipsychotics, steroids, and other psychoactive substances of both natural and synthetic origin. The necessary biological, chemical, and psychological background material for understanding the content of this course will be contained within the course itself.
Rules & Requirements
Credit Restrictions: Students will receive no credit for C62 after taking 62, C100A/Chemistry C130, 102, 104, 110, 130A, 136, C160/Neuroscience C160,<BR/>Integrative Biology 132, Letters and Science C30T, or Psychology C19 . <BR/>
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 4.5 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Presti
Also listed as: L & S C30T/PSYCH C19
MCELLBI 63 Introduction to Functional Neuroanatomy 3 Units
This course emphasizes beginning anatomy of the brain and spinal cord to individuals interested in understanding the dynamics of motor and sensory functions in the human body. Students in the Departments of Education, Psychology, and Integrative Biology, as well as students interested in medicine and the life sciences, are especially encouraged to attend.
Hours & Format
Summer:
4 weeks - 12 hours of lecture per week
6 weeks - 7.5 hours of lecture per week
8 weeks - 6 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Reyes
MCELLBI C64 Exploring the Brain: Introduction to Neuroscience 3 Units
This course will introduce lower division undergraduates to the fundamentals of neuroscience. The first part of the course covers basic membrane properties, synapses, action potentials, chemical and electrical synaptic interactions, receptor potentials, and receptor proteins. The second part of the course covers networks in invertebrates, memory and learning behavior, modulation, vertebrate brain and spinal cord, retina, visual cortex architecture, hierarchy, development, and higher cortical centers.
Rules & Requirements
Prerequisites: High school chemistry or Chemistry 1A; high school biology or BIOLOGY 1A. BIOLOGY 1AL is not required
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology/Psychology C64 after taking Molecular and Cell Biology C61/Letters and Science C30W, 104, 100A/Chemistry C130, Molecular and Cell Biology 110, 130A, 136, 160, C160/Neuroscience C160, or Integrative Biology 132. Students may remove a deficient grade in Molecular and Cell Biology C64/Psychology C64 after Molecular and Cell Biology 64.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 4 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Caporale
Also listed as: PSYCH C64
MCELLBI 84B Sophomore Seminar 1 or 2 Units
Sophomore seminars are small interactive courses offered by faculty members in departments all across the campus. Sophomore seminars offer opportunity for close, regular intellectual contact between faculty members and students in the crucial second year. The topics vary from department to department and semester to semester. Enrollment limited to 15 sophomores.
Rules & Requirements
Prerequisites: At discretion of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1-2 hours of seminar per week
Summer:
6 weeks - 4-6 hours of seminar per week
8 weeks - 3-4 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI 90A Freshman Seminars: Biochemistry and Molecular Biology 1 Unit
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.
Rules & Requirements
Prerequisites: Open to freshmen only
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI 90B Freshman Seminars: Cell and Developmental Biology 1 Unit
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.
Rules & Requirements
Prerequisites: Open to freshmen only
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI 90C Freshman Seminars: Genetics and Development 1 Unit
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.
Rules & Requirements
Prerequisites: Open to freshmen only
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI 90D Freshman Seminars: Immunology 1 Unit
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.
Rules & Requirements
Prerequisites: Open to freshmen only
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI 90E Freshman Seminars: Neurobiology 1 Unit
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.
Rules & Requirements
Prerequisites: Open to freshmen only
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI 91D Immunology 2 - 4 Units
Freshman and sophomore seminars offer lower division students the opportunity to explore an intellectual topic with a faculty member and a group of peers in a small-seminar setting. These seminars are offered in all campus departments; topics vary from department to department and from semester to semester.
Rules & Requirements
Prerequisites: Open to freshmen and sophomores only
Hours & Format
Fall and/or spring: 15 weeks - 2-4 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
MCELLBI C96 Studying the Biological Sciences 1 Unit
Freshmen will be introduced to the "culture" of the biological sciences, along with an in-depth orientation to the academic life and the culture of the university as they relate to majoring in biology. Students will learn concepts, skills, and information that they can use in their major course, and as future science professionals. Restricted to freshmen in the biology scholars program.
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam required.
Instructor: Matsui
Also listed as: INTEGBI C96/PLANTBI C96
MCELLBI 98 Directed Group Study 1 - 4 Units
Lectures and small group discussions focusing on topics of interest, varying from semester to semester.
Rules & Requirements
Prerequisites: Freshmen and sophomores only
Repeat rules: Course may be repeated for credit. Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of directed group study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
MCELLBI 99 Supervised Independent Study 1 - 4 Units
Rules & Requirements
Prerequisites: 3.3 GPA and consent of instructor
Credit Restrictions: One unit of credit is given for every three hours of work in the lab per week to a maximum of 4 units.
Repeat rules: Course may be repeated for credit. Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer:
8 weeks - 1.5-7.5 hours of independent study per week
10 weeks - 1.5-6 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
MCELLBI 100B Biochemistry: Pathways, Mechanisms, and Regulation 4 Units
We survey cellular metabolic pathways, with focus on the underlying chemistry, bioenergetics, and mechanisms. We discuss signaling in the context of a physical chemical understanding of diffusion, transport and molecular interactions. We will highlight the intertwining of signaling and dysregulation with metabolic disorders and cancer, and the production of renewable chemicals such as biofuels. The course is designed for majors in the biochemistry and molecular biology, genetics and development, or immunology emphases.
Rules & Requirements
Prerequisites: C100A/Chemistry C130
Credit Restrictions: Students will receive 3 units for Molecular and Cell Biology 100B after taking Molecular and Cell Biology 102 and no credit after taking Chemistry 135.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Kuriyan, Savage, Alper
MCELLBI C100A Biophysical Chemistry: Physical Principles and the Molecules of Life 4 Units
Thermodynamic and kinetic concepts applied to understanding the chemistry and structure of biomolecules (proteins, DNA, and RNA). Molecular distributions, reaction kinetics, enzyme kinetics. Bioenergetics, energy transduction, and motor proteins. Electrochemical potential, membranes, and ion channels.
Rules & Requirements
Prerequisites: Chemistry 3A or 112A, Mathematics 1A, BIOLOGY 1A and 1AL; Chemistry 3B or 112B recommended
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 5.5 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Also listed as: CHEM C130
MCELLBI 102 Survey of the Principles of Biochemistry and Molecular Biology 4 Units
A comprehensive survey of the fundamentals of biological chemistry, including the properties of intermediary metabolites, the structure and function of biological macromolecules, the logic of metabolic pathways (both degradative and biosynthetic) and the molecular basis of genetics and gene expression.
Rules & Requirements
Prerequisites: BIOLOGY 1A, 1AL, and Chemistry 3B (or equivalent courses). Recommended: a course in physical chemistry
Credit Restrictions: Students will receive 2 units of credit for 102 after taking 100B or C100A/Chemistry C130. Students will receive no credit for 102 after taking 110 and any of 100B or C100A/Chemistry C130. No credit for 102 after taking Chemistry 135.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer:
8 weeks - 6 hours of lecture and 2 hours of discussion per week
10 weeks - 4 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI C103 Bacterial Pathogenesis 3 Units
This course for upper division and graduate students will explore the molecular and cellular basis of microbial pathogenesis. The course will focus on model microbial systems which illustrate mechanisms of pathogenesis. Most of the emphasis will be on bacterial pathogens of mammals, but there will be some discussion of viral and protozoan pathogens. There will be an emphasis on experimental approaches. The course will also include some aspects of bacterial genetics and physiology, immune response to infection, and the cell biology of host-parasite interactions.
Rules & Requirements
Prerequisites: 100, 102 or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Portnoy
Also listed as: PB HLTH C102/PLANTBI C103
MCELLBI 104 Genetics, Genomics, and Cell Biology 4 Units
This course will introduce students to key concepts in genetic analysis, eukaryotic cell biology, and state-of-the-art approaches in genomic medicine. Lectures will highlight basic knowledge of cellular processes with the basis for human diseases, particularly cancer. Prerequisite courses will have introduced students to the concepts of cells, the central dogma of molecular biology, and gene regulation. Emphasis in this course will be on eukaryotic cell processes, including cellular organization, dynamics, and signaling.
Rules & Requirements
Prerequisites: 102
Credit Restrictions: Students will receive 1 unit for Molecular and Cell Biology 104 after completing Molecular and Cell Biology 140 or C142/Integrative Biology C163, or 3 units after completing Molecular and Cell Biology 110 or 130.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 110 Molecular Biology: Macromolecular Synthesis and Cellular Function 4 Units
Molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.
Rules & Requirements
Prerequisites: C100A (may not be taken concurrently); Plan 1 Emphasis 1 (BMB) majors should take 100B prior to 110
Credit Restrictions: Students will receive 3 units of credit for 110 after taking 104.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI C110L General Biochemistry and Molecular Biology Laboratory 4 Units
Experimental techniques of biochemistry and molecular biology, designed to accompany the lectures in Molecular and Cell Biology 100B and 110.
Rules & Requirements
Prerequisites: 110 (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 2-2 hours of lecture and 6-8 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Also listed as: CHEM C110L
MCELLBI C112 General Microbiology 4 Units
This course will explore the molecular bases for physiological and biochemical diversity among members of the two major domains, Bacteria and Archaea. The ecological significance and evolutionary origins of this diversity will be discussed. Molecular, genetic, and structure-function analyses of microbial cell cycles, adaptive responses, metabolic capability, and macromolecular syntheses will be emphasized.
Rules & Requirements
Prerequisites: BIOLOGY 1A and 1B
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 10 weeks - 4.5 hours of lecture and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Ryan
Also listed as: PLANTBI C112
MCELLBI C112L General Microbiology Laboratory 2 Units
Experimental techniques of microbiology designed to accompany the lecture in C112 and C148. The primary emphasis in the laboratory will be on the cultivation and physiological and genetic characterization of bacteria. Laboratory exercises will include the observation, enrichment, and isolation of bacteria from selected environments.
Rules & Requirements
Prerequisites: C112 (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 4 hours of laboratory and 1 hour of discussion per week
Summer: 10 weeks - 6 hours of laboratory and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructors: Komeili, Taga
Also listed as: PLANTBI C112L
MCELLBI C114 Introduction to Comparative Virology 4 Units
This course will provide a comparative overview of virus life cycles and strategies viruses use to infect and replicate in hosts. We will discuss virus structure and classification and the molecular basis of viral reproduction, evolution, assembly, and virus-host interactions. Common features used during virus replication and host cellular responses to infection will be covered. Topics also included are common and emerging virus diseases, their control, and factors affecting their spread.
Rules & Requirements
Prerequisites: Introductory chemistry (Chemistry 1A or 3A-3B or equivalent) and introductory biology (BIOLOGY 1A, 1AL, and 1B or equivalent) and general biochemistry (Molecular and Cell Biology C100A or equivalent--preferably completed but may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Glaunsinger, Jackson
Also listed as: ESPM C138/PLANTBI C114
MCELLBI C116 Microbial Diversity 3 Units
This course for upper-division and graduate students will broadly survey myriad types of microbial organisms, both procaryote and eucaryote, using a phylogenetic framework to organize the concept of "biodiversity." Emphasis will be on the evolutionary development of the many biochemical themes, how they mold our biosphere, and the organisms that affect the global biochemistry. Molecular mechanisms that occur in different lineages will be compared and contrasted to illustrate fundamental biological strategies. Graduate students additionally should enroll in C216, Microbial Diversity Workshop.
Rules & Requirements
Prerequisites: Upper-division standing. C112 or consent of instructor and organic chemistry (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Coates
Formerly known as: 116
Also listed as: PLANTBI C116
MCELLBI 118 The Cancer Karyotype: What it is and What it Does 1 Unit
Mutational cancer theories do not explain why cancers: 1) have clonal individual karyotypes; 2) have polygenic transcriptomes and phenotypes; 3) have flexible karyotypes, which evolve progressive malignancy and drug resistance, but maintain autonomy and even immortality; and 4) Why carcinogens induce cancer only after conspicuously long latent periods of years to decades. To answer these questions, this course tests a new karyotypic theory, which postulates that cancers evolve much like new species.
Rules & Requirements
Prerequisites: 102. 104 recommended
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Duesberg
MCELLBI 130A Cell and Systems Biology 4 Units
This course will provide a detailed discussion of a wide range of topics in cell biology emphasizing experimental approaches and key experiments that have provided important insights. The course is aimed at conveying an understanding of how cellular structure and function arise as a result of the properties of cellular macromolecules. An emphasis will be placed on the dynamic nature of cellular organization and will include a description of physical properties of cells (dimensions, concepts of free energy, diffusion, biophysical properties). Students will be introduced to quantitative aspects of cell biology and a view of cellular function that is based on integrating multiple pathways and modes of regulation (systems biology).
Rules & Requirements
Prerequisites: 102 and 104. Instructors may waive 104 prerequisite for non-Molecular and Cell Biology majors
Credit Restrictions: Students will receive no credit for 130A after taking 130.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 132 Biology of Human Cancer 4 Units
The course is designed for students interested in learning about the molecular and cell biology of cancer and how this knowledge is being applied to the prevention, diagnosis and therapy of cancer. Topics covered include tumor pathology and epidemiology; tumor viruses and oncogenes; intracellular signaling; tumor suppressors; multi-step carcinogenesis and tumor progression; genetic instability in cancer; tumor-host interactions; invasion and metastasis; tumor immunology; cancer therapy.
Rules & Requirements
Prerequisites: 102 or 110 (may be taken concurrently); BIOLOGY 1A, 1AL, 1B
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: 135G
MCELLBI 133L Physiology and Cell Biology Laboratory 4 Units
Experimental analyses of central problems in cell biology and physiology using modern techniques, including DNA cloning and protein biochemistry, fluorescence microscopy of the cytoskeleton and organelles, DNA transfection and cell cycle analysis of cultured mammalian cells, RNA interference and drug treatments to analyze ion channel function in cell contractility and intracellular signaling, and somatosensation.
Rules & Requirements
Prerequisites: 104
Credit Restrictions: Students will receive no credit for 133L after taking 130L.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 7 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
MCELLBI C134 Chromosome Biology/Cytogenetics 3 Units
Survey of behavior, structure, and function of chromosomes with emphasis on behavior in model organisms. Topics include mitosis, meiosis, chromosome aberrations, genome function, dosage compensation, transposons, repetitive DNA, and modern cytological imaging.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Cande, Karpen
Also listed as: PLANTBI C134
MCELLBI 135A Topics in Cell and Developmental Biology: Molecular Endocrinology 3 Units
Molecular mechanisms by which hormones elicit specific responses and regulate gene expression; hormone-receptor interaction; synthesis, transport and targeting of hormones, growth factors and receptors.
Rules & Requirements
Prerequisites: Molecular and Cell Biology 102, BIOLOGY 1A, 1AL, 1B, Chemistry 3A-3B or equivalent, or consent of instructor
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 135A after taking Physiology 142.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Firestone
MCELLBI 136 Physiology 4 Units
Principles of mammalian (primarily human) physiology emphasizing physical, chemical, molecular and cellular bases of functional biology. The following topics will be covered: cellular and membrane ion and nonelectrolyte transport; cell and endocrine regulation; autonomic nervous system regulation; skeletal, smooth and cardiac muscle; cardiovascular physiology; respiration; renal physiology; gastrointestinal physiology. Discussion section led by Graduate Student Instructor will review material covered in lecture.
Rules & Requirements
Prerequisites: BIOLOGY 1A, 1AL, 1B, PHYSICS 8A. PHYSICS 8B recommended
Credit Restrictions: Students will receive no credit for 136 after Integrative Biology 132.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 137 Computer Simulation in Biology 3 Units
Modeling and computer simulation of dynamic biological processes using special graphical interfaces requiring very little mathematical or computer experience. Models are drawn from the current literature to teach concepts and technique. The later part of the course is a workshop for student-selected individual projects. Computer work may be done at home or in the university laboratory.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructors: Macey, Oster
Formerly known as: 136L
MCELLBI 140 General Genetics 4 Units
In-depth introduction to genetics, including mechanisms of inheritance; gene transmission and recombination; transposable DNA elements; gene structure, function, and regulation; and developmental genetics. Some exams may be given in the evening.
Rules & Requirements
Prerequisites: BIOLOGY 1A and 1AL,BIOLOGY 1A
Credit Restrictions: Students will receive 1 unit of credit for Molecular and Cell Biology 140 after completing either Molecular and Cell Biology 104, C142, or Integrative Biology C163.,Students will receive 1 unit of credit for Molecular and Cell Biology 140 after completing Molecular and Cell Biology 104, C142, or Integrative Biology C163.
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 140 General Genetics 4 Units
In-depth introduction to genetics, including mechanisms of inheritance; gene transmission and recombination; transposable DNA elements; gene structure, function, and regulation; and developmental genetics. Some exams may be given in the evening.
Rules & Requirements
Prerequisites: BIOLOGY 1A and 1AL,BIOLOGY 1A
Credit Restrictions: Students will receive 1 unit of credit for Molecular and Cell Biology 140 after completing either Molecular and Cell Biology 104, C142, or Integrative Biology C163.,Students will receive 1 unit of credit for Molecular and Cell Biology 140 after completing Molecular and Cell Biology 104, C142, or Integrative Biology C163.
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 140L Genetics Laboratory 4 Units
Experimental techniques in classical and molecular genetics.
Rules & Requirements
Prerequisites: Molecular and Cell Biology 104 or 140. May be taken concurrently
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 6 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
MCELLBI 141 Developmental Biology 4 Units
An introduction to principles and processes of embryonic and post-embryonic development, stressing mechanisms of cell and tissue interactions, morphogenesis and regulation of gene expression.
Rules & Requirements
Prerequisites: 102 or C100A; BIOLOGY 1A, 1AL, and 1B; 110 or 130 recommended
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: 131
MCELLBI 143 Evolution of Genomes, Cells, and Development 3 Units
This course is intended for upper-division undergraduates seeking an interactive course based on modern concepts in evolution and comparative genomics. The course will emphasize the contribution of molecular evolution to a series of seminal events in life's history: origin of life; origin of cells; origin of eukaryotes; origin of multicellularity; evolution of animal development; human origins.
Rules & Requirements
Prerequisites: BIOLOGY 1A-1B and Molecular and Cell Biology C100A or 102; 104 or 140 recommended
Credit Restrictions: Student will receive no credit for 143 after taking Integrative Biology 163.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructors: King, Levine, Patel
MCELLBI C148 Microbial Genomics and Genetics 4 Units
Course emphasizes bacterial and archaeal genetics and comparative genomics. Genetics and genomic methods used to dissect metabolic and development processes in bacteria, archaea, and selected microbial eukaryotes. Genetic mechanisms integrated with genomic information to address integration and diversity of microbial processes. Introduction to the use of computational tools for a comparative analysis of microbial genomes and determining relationships among bacteria, archaea, and microbial eukaryotes.
Rules & Requirements
Prerequisites: Molecular and Cell Biology C100A/Chemistry C130 or Molecular and Cell Biology 102
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Brenner, Glass
Formerly known as: Plant and Microbial Biology 118
Also listed as: PLANTBI C148
MCELLBI 149 The Human Genome 3 Units
This is an upper division course for majors in MCB with an interest in an in-depth exploration of the forces that shape the human genome and the human population, as well as the ways that human genetic information can be used in medicine, ancestry and forensics. The course will combine lectures and discussion of research papers.
Rules & Requirements
Prerequisites: MCB 140, MCB 104 or equivalent
Credit Restrictions: Students will receive 2 units for Molecular and Cell Biology 149 after taking Integrative Biology 164.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Instructors: Eisen, Meyer, Rokhsar
MCELLBI 150 Molecular Immunology 4 Units
Fundamentals of immunology with emphasis on biochemical and molecular approaches to study of the immune system and its application in medicine and biotechnology. Topics covered include description of the immune system, antibody and T-cell receptor structure and function, genes of the immunoglobulin superfamily, cells and molecular mediators that regulate the immune response, allergy, autoimmunity, immunodeficiency, tissue and organ transplants, and tumor immunology.
Rules & Requirements
Prerequisites: C100A/Chemistry C130, or 102
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 150L Immunology Laboratory 4 Units
Experimental techniques in mammalian molecular biology and cellular immunology. Molecular techniques covered include PCR and recombinant DNA procedures such as gene cloning, gene transfer, DNA sequencing, Southern blot, and restriction mapping. Immunological techniques covered include cell culture and monoclonal antibody production, flow cytometry, ELISA, immunoprecipitation, and western blot.
Rules & Requirements
Prerequisites: Molecular and Cell Biology 150 (may be taken concurrently); consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 8 hours of laboratory and 1 hour of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Formerly known as: Microbiology 103L
MCELLBI 160 Cellular and Molecular Neurobiology 4 Units
Comprehensive introductory survey of cellular and molecular neuroscience, including cellular neurophysiology, ion channel function, synaptic function and plasticity, sensory transduction, and brain development. Includes introduction to molecular basis of neurological disease. Analysis from the level of molecules to cells to simple circuits.
Rules & Requirements
Prerequisites: BIOLOGY 1A and 1AL. Prerequisite or co-requisite: PHYSICS 8B
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: Molecular and Cell Biology C160/Neuroscience C160
MCELLBI 160L Neurobiology Laboratory 4 Units
Experimental analyses of properties and interactions of nerve cells and systems, illustrating principal features and current methods. Techniques employed include computer simulation of neuron properties, electrophysiological recording and stimulation of nerves and cells, digitally enhanced video imaging of outgrowth, fluorescence immunocytochemistry, analysis of sensory: CNS mapping, human-evoked potential recording, sensory psychophysics.
Rules & Requirements
Prerequisites: BIOLOGY 1A, 1AL; PHYSICS 8A-8B, Molecular and Cell Biology C100A/Chemistry C130 or 102; Molecular and Cell Biology 160; or equivalent
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 8 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 161 Circuit, Systems and Behavioral Neuroscience 4 Units
Comprehensive survey of circuits and systems neuroscience, including sensory and motor systems, learning and memory, neuromodulatory systems and brain state and higher functions.
Biological and computational principles of neural circuit function. Analysis from the level of small circuits to behavior.
Rules & Requirements
Prerequisites: Molecular and Cell Biology 160
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 163 Mammalian Neuroanatomy 4 Units
Development, structure (gross and microscopic), and functional relationships of the mammalian nervous system.
Rules & Requirements
Prerequisites: BIOLOGY 1A. BIOLOGY 1AL is not required
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 2 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
MCELLBI 165 Neurobiology of Disease 3 Units
The molecular, cellular, and neural circuit basis of neurological disease. Includes neurochemistry and reward systems, neural development and its disorders, addiction, neurodegenerative and neuropsychiatric disorders. Students will read and discuss primary papers from the research literature.
Rules & Requirements
Prerequisites: Molecular and Cell Biology 160
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Caporale
MCELLBI 166 Biophysical Neurobiology 3 Units
Electrochemistry and ion transport phenomena, equivalent circuits, excitability, action potentials, voltage clamp and the Hodgkin-Huxley model. Biophysical properties of ion channels. Statistical and electrophysiological models of synaptic transmission, Quantitative models for dendritic structure and neuronal morphogenesis. Sensory transduction, cellular networks as computational devices, information processing and transfer.
Objectives & Outcomes
Course Objectives: 1) Derive equations for Nernst and GHK membrane potential from fundamental physics concepts.
2) Describe the experiments and theory underlying the Hodgkin-Huxley model.
3) Understand biophysical properties of gating particles called ion channels.
4) Apply and solve equivalent circuit models to describe resting and excitable cells, synaptic transmission and sensory transduction.
5) Use Poisson, Gaussian and binomial distributions to analyze the gating of ion channels, synaptic transmission, and absolute sensitivity of vision.
6) Model dendritic structure based on quantitative descriptors of shape and energy minimization theory.
7) Explain experiments and models of sensory transduction, neuronal integration and lateral inhibition.
Rules & Requirements
Prerequisites: BIOLOGY 1A, 1AL, PHYSICS 8A-8B, Chemistry 1A, 3A/3AL-3B, or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Elul, Isacoff, Miller
MCELLBI 180 Undergraduate Teaching of Biology 1A Laboratory 1 or 2 Units
Course consists of a weekly three-hour training session that focuses on laboratory techniques, instructional aids, and problem solving, plus an additional three hour weekly laboratory where the UGSI is required to assist a GSI in the instruction of laboratory (answering questions, providing demonstrations, etc.).
Rules & Requirements
Prerequisites: BIOLOGY 1A, 1AL with a minimum grade of B. Appointment as a UGSI in biology by consent of instructor. Restricted to undergraduate students
Repeat rules: Course may be repeated for a maximum of 4 units.Course may be repeated for a maximum of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of session per week
Summer: 8 weeks - 3 hours of session per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
MCELLBI 180C Undergraduate Teaching of Molecular and Cell Biology 32 Laboratory 1 - 2 Units
Course consists of a weekly three-hour training session that focuses on laboratory techniques, instructional aids, and problem solving, plus an additional three-hour weekly laboratory where the UGSI is required to assist a GSI in the instruction of laboratory (answering questions, providing demonstrations, etc.). Students will be graded on lecture and laboratory attendance and preparation of one quiz.
Rules & Requirements
Prerequisites: 32, 136, or Integrative Biology 132 and Molecular and Cell Biology 32L or Integrative Biology 132L laboratory courses in physiology with minimum grades of B. Appointment as a UGSI in physiology by consent of instructor
Repeat rules: Course may be repeated for a maximum of 4 units.Course may be repeated for a maximum of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of session per week
Summer:
6 weeks - 8 hours of session per week
8 weeks - 6 hours of session per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam required.
MCELLBI H196A Honors Research 1 - 4 Units
Individual research and thesis preparation under the supervision of a faculty member. Acceptance to the Molecular and Cell Biology Honors Program is required. Contact the MCB Undergraduate Affairs Office, 3060 Valley Life Sciences Building, for application and details. Honor students must complete at least two semesters of research, taking a minimum of 4 units and a maximum of 8 units of H196A-196B. If desired, one semester of 199 can be used to replace H196A.
Rules & Requirements
Prerequisites: Senior honors status and consent of instructor
Repeat rules: Course may be repeated for a maximum of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer: 8 weeks - 1.5-7.5 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
MCELLBI H196B Honors Research 1 - 4 Units
Individual research and completion of thesis under the supervision of a faculty member. This course satisfies the thesis requirement for the Molecular and Cell Biology Department Honors Program. Contact the MCB Undergraduate Affairs Office, 3060 Valley Life Sciences Building, for program details and an application. Honor students must complete at least two semesters of research, taking a minimum of 4 units and a maximum of 8 units of H196A-196B. One semester of H196B is required.
Rules & Requirements
Prerequisites: Senior honors status and consent of instructor
Repeat rules: Course may be repeated for a maximum of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer: 8 weeks - 1.5-7.5 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
MCELLBI 197 Supervised Internship 1 Unit
Supervised experience relevant to specific topics of biology in off-campus organizations. Written report and evaluation from internship supervisor required.
Rules & Requirements
Prerequisites: Consent of MCB Faculty, restricted to MCB majors and prospective majors only. Certification from supervisor that credit is required
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of internship per week
Summer: 8 weeks - 6 hours of internship per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
MCELLBI 198 Directed Group Study 1 - 4 Units
Lectures and small group discussions focusing on topics of interest, varying from semester to semester.
Rules & Requirements
Prerequisites: Upper division standing
Repeat rules: Course may be repeated for credit. Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of directed group study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
MCELLBI 199 Supervised Independent Study and Research 1 - 4 Units
Enrollment restrictions apply; see the Introduction to Courses and Curricula section of this catalog.
Rules & Requirements
Prerequisites: Consent of instructor
Repeat rules: Course may be repeated for credit. Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer:
6 weeks - 1-4 hours of independent study per week
8 weeks - 1-4 hours of independent study per week
10 weeks - 1-4 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Faculty
Professors
Georjana Barnes, Professor. Biochemistry, genetics, cancer, biology, microtubule cytoskeleton, cell cycle controls, cellular imaging.
Research Profile
James M. Berger, Professor. Structural & mechanistic biochemistry of macromolecular assemblies & machines, multiprotein complexes; DNA replication, maintenance of chromosome superstructure;catalytic mechanism & enzyme/small-molecule inhibitor studies.
Research Profile
David Bilder, Professor. Genetics, cancer, Drosophila, cell biology, cell polarity, tumor suppressor, epithelial architecture, polarity, and proliferation control.
Research Profile
W. Zacheus Cande, Professor. Genetics, cell biology, microbial biology, plant biology.
Research Profile
Jamie H. D. Cate, Professor. Molecular basis for protein synthesis by the ribosome, RNA, antibiotics, a thermophilic bacterium, escherichia coli.
Research Profile
Kathleen Collins, Professor. RNA, telomerase, Telomere function, Telomere replication.
Research Profile
Yang Dan, Professor. Neuronal circuits, mammalian visual system, electrophysiological, psychophysical and computational techniques, visual cortical circuits, visual neurons.
Research Profile
Abby Dernburg, Professor. Genomics, chromosome remodeling and reorganization during meiosis, Down syndrome, DNA.
Research Profile
Andrew Dillin, Professor.
Jennifer A Doudna, Professor. RNA machines, hepatitis C virus, RNA interference, ribosomes.
Research Profile
David G. Drubin, Professor. Cellular morphogenesis, plasma membrane dynamics, microtubule cytoskeletons, cytoskeletal proteins, morphological development.
Research Profile
Peter H. Duesberg, Professor. Genetic structure of retroviruses, carcinogenesis, aneuploidy, virology, HIV-AIDS.
Research Profile
Michael B. Eisen, PhD, Professor. Genomics, genome sequencing, bioinformatics, animal development.
Research Profile
Marla B. Feller, Professor. Neurophysiology, developmental neuroscience.
Research Profile
Gary L. Firestone, Professor. Cancer, steroid hormones, molecular endocrinology, tumor biology, growth factors, dietary compounds, tumor cells, glucocorticoids.
Research Profile
Gian Garriga, Professor. Developmental neurobiology; molecular genetics, development of nervous systems, cell division, cell migration, axonal pathfinding, caenorhabditis elegans.
Research Profile
Iswar Krishna Hariharan, Professor.
Rebecca Heald, Professor. Cell division, Xenopus, mitotic spindle assembly and function, size control of intracellular structures.
Research Profile
James H Hurley, Professor.
Ehud Y. Isacoff, Professor. Ion channel function, synaptic plasticity, neural excitability, synaptic transmission, the synapse.
Research Profile
Douglas E. Koshland, Professor. Higher order chromosome structure, genome integrity, sister chromatid cohesion, chromosome condensation, desiccation tolerance, microbial genetics.
Research Profile
Richard H Kramer, Professor. Cells, synaptic transmission, chemical signaling between neurons, ion channels, electrical signals, chemical reagents, synapses.
Research Profile
John Kuriyan, Professor. Structural and functional studies of signal transduction, DNA replication, cancer therapies, phosphorylation.
Research Profile
Michael S Levine, Professor. Regulation of enhancer-promoter interactions, gene networks, animal development and disease, drosophila embryo, immune response in drosophila larvae, differentiation of the notochord and heart in the sea squirt, whole-genome analysis.
Research Profile
Kunxin Luo, Professor. Signal transduction pathways, mechanisms controlling the receptor kinases, regulation of mammary epithelial cell differentiation, breast carcinogenesis.
Research Profile
Terry E. Machen, PhD, Professor. Physiology pathophysiology secretory epithelial cells, airway, ion transport, cell regulationm, imaging microscopy, calcium pH redox, electrophysiology, green fluorescent protein, genetic targeting, innate immune defense.
Research Profile
Susan Marqusee, Professor. Amino acids, determinants of protein structure and folding, biophysical, structural and computational techniques, translocation, protein synthesis.
Research Profile
Barbara J Meyer, Professor. Developmental biology, gene expression, genetic determination of sex, regulatory genes, chromosome dynamics, X-chromosome.
Research Profile
John Ngai, Professor. Nervous system, molecular and cellular mechanisms of olfaction, detection of odors, odorant receptors, olfactory neurons, DNA microarray technologies, genome-wide patterns of gene expression.
Research Profile
Nipam Patel, Professor. Genetics, evolution, crustaceans, insects, arthropods, homeotic (Hox) genes, segmentation, embryonic pattern formation, neural patterning.
Research Profile
Mu-Ming Poo, Professor. Neurobiology, cellular and molecular mechanisms, axon guidance, synapse formation, activity-dependent refinement of neural circuits.
Research Profile
Michael P Rape, PhD, Professor. Cancer, protein degradation, siRNA, Berkeley Screening Center.
Research Profile
Jasper D. Rine, Professor. Biology, cell biology, DNA replication, gene regulation, saccharomyces cerevisiae, genetic analysis, genome, cholesterol biosynthetic pathway, modification of proteins, prenylated proteins.
Research Profile
Donald C. Rio, Professor. Molecular genetics, drosophila melanogaster, transposable elements, RNA splicing, nucleic acid rearrangement reactions, P elements and their cellular host, HIV, proteomic diversification, nucleoprotein complexes.
Research Profile
Ellen Robey, Professor. Fate determination in the T-lymphocyte lineage, T cell development in the mouse, thymic development, cellular maturation, parasitic infection, chronic infection, host-pathogen interactions, Toxoplasma gondii.
Research Profile
Randy W Schekman, Professor. Saccharomyces cerevisiae, organelle assembly, intracellular protein transport, assembly of cellular organelles, Alzheimer's Disease.
Research Profile
Kristin Scott, Professor. Nerve cell connectivity in developing nervous systems, taste perception in the fruit fly, taste neural circuits, sensory maps in the brain.
Research Profile
Karsten Weis, Professor. Molecular biology, proteins, macromolecular transport, nucleus of eukaryotic cells, DNA transcription, mRNA translation, nuclear pore complex, the cytoplasm, cerevisiae and metazoan cells, transport of macromolecules, the cell cycle.
Research Profile
David A. Weisblat, Professor. Developmental biology, glossiphoniid leech embryos, evolution of different animal taxa, microinjection of cell lineage tracers.
Research Profile
Matthew D. Welch, Professor. Biology, cell motility, the role of the actin cytoskeleton in cell locomotion, shape change, actin filament assembly, bacterial and viral pathogens.
Research Profile
Astar Winoto, PhD, Professor. Cancer, genomics, apoptosis, innate immunity and infectious diseases, cell cycle, signal transduction, immune tolerance.
Research Profile
Qiang Zhou, PhD, Professor. Biochemistry of HIV gene expression, transcriptional elongation, Tat activation, stage of transcriptional elongation, HIV replication, anti-HIV therapy.
Research Profile
Associate Professors
Gregory M. Barton, Associate Professor. Immunology, cell biology, infectious disease, innate immunity.
Research Profile
Laurent Coscoy, Associate Professor. Immunology, viruses, viral infection, immune responses, immune evasion.
Research Profile
Dan Feldman, PhD, Associate Professor. Neurobiology, learning, neurophysiology, sensory biology.
Research Profile
Nicole King, Associate Professor. Genetics, developmental biology, biology, choanoflagellates, evolution of multicellular animals, comparative genomics, molecular phylogenetics, eukaryotes, cadherins, host-microbe interactions.
Research Profile
Henk Roelink, PhD, Associate Professor. Stem cells, neural development, embryonic induction.
Research Profile
Bill Sha, Associate Professor. B cell gene regulation, fate determination, gene regulatory pathways, antibody-secreting plasma cells, memory B cells, apoptotic cells, B7 costimulatory ligands.
Research Profile
Russell E. Vance, Associate Professor. Immunology, microbiology, infectious disease, molecular and cell biology.
Research Profile
Assistant Professors
Hillel Adesnik, Assistant Professor.
Helen Bateup, Assistant Professor.
Diana Bautista, PhD, Assistant Professor. Ion channels, sensory physiology, chemosensation, touch, thermosensation, somatosensory system.
Research Profile
Gloria A Brar, PhD, Assistant Professor.
Rachel B Brem, Assistant Professor. Genetics of regulatory variation.
Research Profile
Lin He, Assistant Professor.
Dirk Hockemeyer, Assistant Professor.
Nicholas Ingolia, PhD, Assistant Professor.
Bryan A. Krantz, PhD, Assistant Professor. Protein folding, spectroscopy, electrophysiology, biophysical studies of transmembrane protein translocation, microbial toxins.
Research Profile
Polina V Lishko, PhD, Assistant Professor.
Craig T. Miller, PhD, Assistant Professor. Genetics, developmental biology, evolutionary biology, evolution, quantitative genetics, developmental genetics, evolutionary genetics, craniofacial development.
Research Profile
Kaoru Saijo, Assistant Professor.
David Savage, PhD, Assistant Professor. Synthetic biology and metabolism.
Research Profile
Elcin Unal, Assistant Professor.
Roberto Zoncu, PhD, Assistant Professor.
Adjunct Faculty
Gary H. Karpen, Adjunct Faculty. Gene expression, cell biology, chromosome structure and function, drosophila melanogaster, centromere identity and function.
Research Profile
Robert T. Tjian, Adjunct Faculty. Eukaryotic molecular biology; biochemistry, cellular differentiation, chromatin function, RNA synthesis.
Research Profile
Lecturers
P. Robert Beatty, Lecturer.
Helen Lew, PhD, Lecturer.
David E. Presti, Lecturer.
Gary Joseph Wedemayer, Lecturer.
Contact Information
Department of Molecular and Cell Biology
142 Life Sciences Addition
Phone: 510-642-2651
Cell & Developmental Biology Division Chair
Rebecca Heald, PhD
311A Life Sciences Addition
Phone: 510-643-5493
Chair, Undergraduate Affairs Committee
Eva Nogales
708C Stanley Hall
Phone: 510-642-0557
Undergraduate Affairs Manager
James Depelteau, MA
3060 Valley Life Sciences Building
Phone: 510-643-8895
Undergraduate Staff Adviser
Anwar Thomas, MA
3060 Valley Life Sciences Building
Phone: 510-643-8895