The course will survey the field of the human brain, with introductory lectures on the concepts of aging, and brief surveys of normal neuroanatomy, neurophysiology, neurochemistry, and neuropsychology as well as methods such as imaging, epidemiology, and pathology. The neurobiological changes associated with aging will be covered from the same perspectives: neuropsychology, anatomy, biochemistry, and physiology. Major neurological diseases of aging including Alzheimer's and Parkinson's disease will be covered, as will compensatory mechanisms, neuroendocrine changes with aging, depression and aging, epidemiology of aging, and risk factors for decline.

This course will survey the field of Alzheimer's disease (AD) from a biological and public health perspective by reading original research papers in the fields of medicine, neuroscience, and epidemiology. The course will begin with a historical survey of the concept of AD, followed by a description of clinical and neuropathological features. Subsequent classes will cover the genetics and molecular biology of the disease, as well as biomarkers, epidemiology, risk factors, treatment, development of new diagnostic approaches, and ethical issues. The course will also serve as a model for the analysis of complex diseases with multiple genetic and environmental causes, and late onset neurodegenerative diseases. The course will also serve as a model for the analysis of complex diseases with multiple genetic and environmental causes and late-onset neurodegenerative disease.

An introductory course designed to provide a general understanding of the nervous system including how it functions, how it develops, and how it changes with learning and memory. Analysis from the level of molecules to cells to simple circuits to complex networks to higher brain functions.

Physical-chemical basis of membrane potentials, electrotonus, action potential generation and propagation, synaptic transmission, sensory receptor function, and volume conductor potentials.

Advanced coverage of current research problems in systems-level neuroscience, and experimental and computational techniques used for these studies.

Advanced level coverage of current research problems in the embryonic and post-embryonic development of invertebrate and vertebrate nervous systems.

This course provides an introduction to the theory of neural computation. The goal is to familiarize students with the major theoretical frameworks and models used in neuroscience and psychology, and to provide hands-on experience in using these models. Topics include neural network models, supervised and unsupervised learning rules, associative memory models, probabilistic/graphical models, and models of neural coding in the brain.

Seminar on the presentation and evaluation of research results for first-year neuroscience graduate students. During the first weeks, faculty present their research (FERPS); later, students present individual research results and evaluate their own and each other's work. Course enrollment limited to 15.

Closely supervised, intensive laboratory experimental research under the direction of an individual faculty member. For first-year neuroscience graduate students, this course will provide an introduction to experimental methods and research approaches in the different areas of neuroscience. Grade awarded on completion of sequence, which includes 3 ten-week laboratory rotations spread out over the fall and spring semesters.

Closely supervised, intensive laboratory experimental research under the direction of an individual faculty member. For first-year neuroscience graduate students, this course will provide an introduction to experimental methods and research approaches in the different areas of neuroscience. Grade awarded on completion of sequence, which includes 3 ten-week laboratory rotations spread out over the fall and spring semesters.

For graduate students in neuroscience in their second or later years. During the summer, the course will count for 3-6 units. Individual research under faculty supervision. In this course each graduate student conducts basic thesis and dissertation research after successful completion of the first-year laboratory rotation, Neuroscience 291A-291B. Laboratory work provides the basis for students' thesis research, preparation for the preliminary examination, and continued progress toward completion of Ph.D. dissertation.

For graduate students in neuroscience in their second or later years. Two hours of seminar per week which complements the individual laboratory work under faculty supervision. Seminar will review current scientific literature and discuss original research performed by faculty, postdoctoral fellows, scientists, and graduate students in individual faculty laboratories.

This course will encompass three important facets of graduate education in the neurosciences: 1) Development of research presentation skills: fourth and fifth year graduate students will present seminars based on their ongoing dissertation research. Preparation and critiques of presentations will focus on organization of conceptual issues, data presentation, and summarization. 2) Exposure to current topics in neuroscience: faculty speakers will present on current issues and topics relevant to scientific development in the neurosciences, such as technical methods, application of analytical and statistical techniques, and organization and preparation of competitive fellowship and other grant applications. 3) Seminar preparation: a crucial aspect of graduate education is the interaction of students with invited seminar speakers - who are often leaders in their fields. A selected number of class meetings will be devoted to the review of scientific articles published by upcoming seminar speakers and/or other related articles in the field.

Course that focuses on topical subjects in specific fields of neuroscience.