Graduate seminar in vision science.

Graduate seminar in vision science.

Geometrical methods applied to the optics of lenses, mirrors, and prisms. Thin lens eye models, magnification, astigmatism, prism properties of lenses, thick lenses.

Principles of optical systems, principles and clinical applications of aperatures and stops, aberrations and optical instruments. Optics of the eye. Selected topics in physical optics, diffraction, interference, polarization.

Psychophysical basis for clinical tests in acuity, perimetry, and color vision. The visual stimulus and photometry. Visual receptors. Psychophysical method and visual threshold. Light sensitivity. Contrast sensitivity. Light and dark adaptation. Temporal and spatial properties of visual function. Color vision and abnormalities. Changes with age and disease. Visual illusion. Basis for advanced diagnostic procedures.

This course focuses on the anatomy and physiology of the eyeball. Overview of the gross anatomy of the eye followed by eye-relevant cellular and molecular biology. Cellular and molecular details of structure and function of each of the various non-neural components.

Structure and function of the tissues of the eye, ocular appendages, and the central visual pathways. Basic concepts of physiological, neurological, embryological, and immunological processes as they relate to the eye and vision. Foster an appreciation of the pathophysiology of various disease processes. Convey the importance of anatomy and physiology in the medical approach to ocular disease processes.

Problem-based learning approach using clinical case examples. Continuation of 206A-206B.

Structure and function of the neurosensory retina, photoreceptors, RPE including blood supply. Current concepts of etiology and management of major retinal conditions. Overview of diagnostic techniques in retinal imaging, electrophysiologic testing and new genetic approaches. Structure and function of the early visual pathway including retinal ganglion cells, optic nerves, lateral geniculate nucleus and visual cortex. Pupillary responses. Specialization in the visual cortex.

Introduction for graduate students to basic principles of classic and modern geometric optics (thick lens systems, mirrors, prisms, apertures, and stops) and physical optics (interference, diffraction, and polarization) with emphasis on dioptrics of the human eye (including schematic eyes, aberrations, and entoptic phenomena).

Introduction for graduate students. Visual pathways will be considered from retina to lateral geniculate to visual cortex. Basic organization at each stage will be covered. Primary focus will be studies of receptive field characteristics and associated visual function. Development and plasticity of the same visual pathways will also be covered. Evidence and implications will be explored from controlled rearing procedures and studies of abnormal visual exposure.

Introduction for graduate students to a general survey of the orbit, anterior and posterior segment of the eye, extraocular muscles, and neuroanatomy of the eye. Vegetative physiology of the cornea and tear film, aqueous humor, crystalline lens, vitreous humor, epithelial tissue (iris, ciliary body and retina), and photochemistry.

Introduction for graduate students to sensory aspects of light and color vision including: psychophysical methods, spectral response of the eye, mechanisms of sensitivity control, dark adaptation, color discrimination, mechanisms of normal and defective color vision.

Introduction for graduate students to human spatial vision including contrast sensitivity, visual acuity, and spatial localization. Introduction to eye movements, motion perception, and motor and sensory aspects of binocular vision including pursuit, vergence, and saccadic eye movements, accommodation, stereopsis, and binocular space perception. Perception of real and apparent motion.

The primary focus of this course is to teach the molecular basis of vertebrate eye development and related disease. This course will cover some of the basic principles of molecular and cell biology, commonly used techniques and experimental approaches, as well as the biological mechanisms for vertebrate eye development and related eye diseases. Recent progress in identifying important ocular genes and the approaches used to identify them will be discussed.

Development of the eye and visual system. Normal development of the eye, retina, and central visual pathways. Effects of visual deprivation. Assessment of optical and visual function in human infants. Refraction and refractive error in infants and children. Development of visuomotor function, spatial vision, color vision, binocular vision, and depth perception.

Neuro-anatomical pathways for the control of eye position and movement; gaze holding, image stabilization and tracking eye movement systems; oculomotor signs of disorders of the central nervous system (palsies, nystagmus, opthalmoplegia, cog-wheel pursuits, saccadic dysmetria); the near visual-motor response and the synergistic coupling of accommodation and convergence; binocular misalignment (heterophoria and fixation disparity); and presbyopia.

Perception of space, direction, and distance. Binocular retinal correspondence, horopters, differential magnification effects and anomalies of binocular vision development. Sensory vision, local stereopsis, static and dynamic stereopsis, binocular depth cues.

This seminar will examine a range of ethical issues that arise in the process of doing science. Beginning with the philosophical and social foundations, we will consider the pathogenesis of fraud, statistics and deception, the ethics of authorship and publication, research with human subjects, the use of animals, the definition(s) of misconduct and the difference between misconduct and questionable research practices, the relationship between industry and science, and finally, the responsibilities and obligations of the scientist in society.

The course will provide an overview of visual cognitive neuroscience, drawing from neuroanatomy, neurophysiology in humans and animal models, psychophysics, neuroimaging, neuropharmacology, neuropsychology, and computational models of vision and cognition. Topics will include basic anatomy and physiology of the mammalian visual system, motion perception and processing, depth perception and representation of visual space, brightness and color, object and face recognition, visual attention, developmental and adult plasticity, perceptual learning, multisensory integration, and visual awareness.

This course provides an introduction to the theory of neural computation. The goal is to familiarize students with the major theoretical frameworks and models used in neuroscience and psychology, and to provide hands-on experience in using these models. Topics include neural network models, supervised and unsupervised learning rules, associative memory models, probabilistic/graphical models, and models of neural coding in the brain.

This course provides an introduction to the theory of neural computation. The goal is to familiarize students with the major theoretical frameworks and models used in neuroscience and psychology, and to provide hands-on experience in using these models. Topics include neural network models, supervised and unsupervised learning rules, associative memory models, probabilistic/graphical models, and models of neural coding in the brain.

Paradigms for computational vision. Relation to human visual perception. Mathematical techniques for representing and reasoning, with curves, surfaces and volumes. Illumination and reflectance models. Color perception. Image segmentation and aggregation. Methods for bottom-up three dimensional shape recovery: Line drawing analysis, stereo, shading, motion, texture. Use of object models for prediction and recognition.

Group studies of selected topics. Advanced studies in various subjects through special seminars on topics to be selected each year, informal groups studying special problems, group participation in experimental problems and analysis.

Research.

Instruction in teaching methods and materials, in vision science and optometry; practice teaching in classrooms and laboratory.

Individual study for the comprehensive requirements in consultation with the adviser in vision science.

Individual study in consultation with the adviser in vision science, intended to provide an opportunity for qualified students to prepare themselves for the various examinations required for the Ph. D.