This is an archived copy of the 2013-14 catalog. To access the most recent version of the catalog, please visit http://bulletin.berkeley.edu/.

Integrative Biology

College of Letters and Science
Department Office: 3060 Valley Life Sciences Building, (510) 642-5024 

Chair: John Huelsenbeck, PhD
Department WebsiteIntegrative Biology 


Overview

The Department of Integrative Biology offers a program of instruction that focuses on the integration of structure and function that influences the biology, ecology, and evolution of organisms. It investigates integration at all levels of organization from molecules to the biosphere, and in all branches of the tree of life: plants, animals, fungi, and microbes.

The department draws from many traditional and emerging fields and levels of biological organization in forging new research directions and answering traditional questions in new ways. The faculty has special strengths in the disciplines of functional morphology, organismal physiology, animal behavior, biomechanics, ecology, systematic biology, paleobiology, population genetics, and evolution.

Students who major in integrative biology will gain both a broad and deep knowledge in the biological sciences, which provides an excellent foundation for those interested in the biology of organisms, populations, and communities, particularly students who might wish to pursue graduate studies in any of the subdisciplines listed above or related emerging research areas. It also provides superb training for students interested in health-related professions (medicine, dentistry, veterinary medicine, physical therapy, nursing, pharmacy, optometry, etc.) or allied careers in biology (e.g., psychology, sociobiology, forestry, wildlife conservation, environmental and resource management, law, etc.).

Through laboratory and/or field courses, independent research projects, or involvement in faculty or graduate student research, students will gain an understanding of scientific logic and methods, through experimental or comparative approaches, including the investigation of historical patterns and processes.


Courses for Nonmajors

The department offers a series of courses for students not specializing in integrative biology. These courses provide instruction in the general principles of biology from a variety of viewpoints, ranging from the molecular level through behavior and evolution. Each year, a variety of seminars are available for freshmen (IB 24) and sophomores (IB 39, IB 84) to introduce them to areas of integrative biology.


Major Requirements

Note: All courses must be taken for a letter grade.

Lower Division

The foundation for this major includes a basic one-year course in biology, general chemistry, organic chemistry, physics, and one year of mathematics. Additional coursework in mathematics, statistics, biochemistry, and multiple languages may be helpful for those planning on graduate and/or professional studies.

Required of all students in the major: Biology 1A (3), 1AL (2), 1B (4); Chemistry 1A (3), 1AL (2), 3A (3), 3AL (2), 3B (3), 3BL (2); (3); Mathematics 1A (4) and 1B (4) or 10A (4) and 10B (4); Physics 8A (4), 8B (4).

With approval of an adviser, more advanced courses may be substituted for those listed above.

Upper Division

This curriculum is designed to provide the intellectual tools and techniques necessary to conduct multidisciplinary work in the areas of organismal biology and to prepare students as broad-thinking biologists. No formal specialization is possible as an undergraduate; however, as of fall 2010, students can select courses to reflect interests and areas of focus in one of two "tracks" within the major in order to meet all upper division requirements.

Students must complete at least one course in evolution/genetics, as well as two courses that include laboratory and/or field work to provide experience and methodologies for study of both living and extinct organisms; three or more additional courses from designated requirement lists (totaling at least 24 upper division units) will complete the undergraduate major in integrative biology.

All students will complete one course from a designated list of evolution/genetics courses, and will select one of two tracks:

  1. Ecology, Evolution and Organismal Biology
  2. Human Biology and Health Science

Within each track, at least three additional Integrative Biology courses, falling under designated categories (Ecology, Behavior, and Diversity or Structure, Function, and Human Health), to be selected in consultation with a department adviser, and at least two courses that include significant laboratory or field biology components will be required.

The minimum total upper division units required to complete the major is 24. Students should plan to take additional upper division courses to reflect areas of interest and intellectual development. In order to meet this minimum, a list of select courses from alternative departments will be provided to allow for some upper division elective coursework. Further, up to three units of upper division, inquiry-based research may be counted toward major completion. Please contact departmental advisers for details.

Note: Students who declared Integrative Biology prior to fall 2010 shall contact the Undergraduate Student Services office in 3060 VSLB for specific questions or concerns regarding major completion.

The department website  presents greater information about planning a major within this field, such as lists of courses applicable to each major requirement and sample semester-by-semester course schedule plans. Please visit the website  to explore undergraduate requirements and options.

Juniors and seniors are encouraged to pursue independent study research (IB 199 or IB 191) under the sponsorship of a faculty member. Interested students should have completed at least 60 units of credit and be in good academic standing. One can consider possible research opportunities by visiting the webpages  of various Department of Integrative Biology faculty, graduate students, and affiliated research centers, museums, and collections.

Note: Transfer students with 56-70 units must complete all lower division requirements before transferring to UC Berkeley.

Honors Program

Students with a minimum UC grade point average (GPA) of 3.3 overall and in the major should consider participating in the honors program. They must identify an appropriate faculty sponsor who agrees to advise them on an original research project they wish to do and enroll in two semesters (six units) of the honors thesis course (H196A-196B). These students must present the results of that work in the form of a written report, the honors thesis, and a poster presentation at Cal Day. In order to graduate with honors, students must maintain a minimum 3.3 GPA overall and in the major.


Graduate Program in Integrative Biology

Biological phenomena occur at various levels of structural organization, ranging from molecules to organisms, and from populations to the global ecosystem. Integrative Biology takes a whole-organism approach, extending from the genome and proteome through organismal traits (phenotypes), to communities and ecosystems. Through the coordinated study of multiple levels of biological organization over a broad range of spatial and temporal scales, Integrative Biology offers a unique approach to understanding fundamental questions concerning the evolution and maintenance of biological diversity, including organismal form and function, and ecological and ecosystem processes. This multidimensional approach underpins our graduate program, where students combine observational, experimental, and comparative approaches with the development of theory, and apply concepts and techniques from the biological sciences and other disciplines.

Students in the PhD program generally apply to work with one or two faculty members whose research interests match those of the applicant. Some groups in the department employ a system of rotation among several labs. Requirements include passage of a qualifying exam, one year of teaching experience, and an advanced evolution course. The central part of the program is the dissertation, incorporating original research that builds on the student’s particular interest and background.

For more information please go to our website.


Research Facilities

The Botanical Garden, located on 34 acres in Strawberry Canyon, provides opportunities for research with living plants, supplies and teaching material for classes on campus, and serves as an outdoor laboratory for students. Independent student and internship opportunities are available in horticulture and plant conservation. The garden is organized primarily by geographic region: California, South America, Mexico/Central America, South Africa, Australasia, Mediterranean, Eastern North America, and Asia. Specialized collections include succulents and cacti, carnivorous plants, orchids, ferns, roses, tropical plants, a Chinese medicinal herb garden, and an herb garden. Laboratory and greenhouse facilities are available at the Botanical Garden Plant Conservation Research Center. For further information about events, programs, and opportunities, go to the Botanical Garden website.  Inquiries can be addressed to the director by mail at UC Botanical Garden, 200 Centennial Drive #5045, Berkeley, CA 94720-5045; emailed to garden@berkeley.edu , or by calling (510) 643-2755.

The Cancer Research Laboratory (CRL) is a research institute on the Berkeley campus that carries on a research, teaching, and service program designed to foster interdepartmental participation in cancer research. The central research program represents a multidisciplinary approach to an understanding of the mechanism of neoplastic transformation using a variety of systems. Graduate student and postdoctoral research programs are supported in various areas of tumor biology: biochemistry, cell biology, endocrinology, genetics, immunology, molecular biology, and tumor virology. Currently, CRL provides advanced technical resources to cancer and biomedical researchers in the areas of advanced microscopy, flow cytometry, gene targeting/transgenic mouse technology, human stem cell facility, and an infectious disease facility. Instrumentation in the facilities is operated by highly trained staff who offer instruction in the methods and techniques associated with each facility. For more information, go to the CRL website.

The Center for Interdisciplinary Bio-inspiration in Education and Research (CIBER) has been established to lead in the development of a new field of Integrative Systems Biomechanics that moves biology toward greater integration with other disciplines such as physics, mathematics and engineering to a degree not seen before. The discipline focuses on the physics of how organisms function and interact with their environment. The goal is to discover basic physical principles that can be applied to a diversity of organisms and unique innovations. The fluid and solid mechanics of organisms are examined using direct experimentation, comparative and phylogenetic approaches and both mathematical and physical modeling. Using this approach, the next generation of scientists and engineers will gain experience in collaboration across disciplines as well as how to extract principles in biology that inspire novel design in engineering. In addition to developing innovative methods of teaching and research, CIBER has established an interdisciplinary teaching laboratory that allows students in undergraduate as well as graduate courses to address challenging problems that will give them a meaningful interdisciplinary learning experience. These facilities are being used in a number of existing and new courses, at both the undergraduate and graduate levels. For more information on CIBER, see the website.

The Center for Stable Isotope Biogeochemistry (CSIB), located on campus, is an analytical facility established as a University education, research, training, and service unit. The center provides high precision, state-of-the-art instrumentation for analyzing the stable isotope composition of a diverse array of materials (e.g., plant and animal tissue samples, soils, atmospheric gasses, water, specific compounds, organic matter, etc.), as well as space for purifying, extracting, and preparing sample material for analysis. The center also serves as a focal point for research and training for many of our programs at Berkeley (e.g., in Biology, Ecology, Paleontology, Anthropology, Geography, Chemistry, Hydrology, Atmospheric, and Soil Sciences). The specialized equipment housed in the facility serves a broad range of student, postdoctoral, and faculty needs. This equipment includes several gas phase isotope ratio mass spectrometers (IRMS); these mass spectrometers have the capabilities of analyzing the isotopic composition of hydrogen, carbon, oxygen, nitrogen, and sulfur in biological and geological samples, gasses (biogenic and atmospheric), and water. In addition to the instrument laboratory, the center houses a fully-equipped sample extraction and preparation laboratory for handling a full range of sample types. For more information, see the CSIB website.

The Field Station for Behavioral Research is a research institute that supports behavioral studies on animals under natural and seminatural conditions. Situated on 20 acres of wooded hillside at the top of Strawberry Canyon two miles from the central campus, the field station maintains and observes a variety of animal species. Faculty from several Berkeley departments including Integrative Biology conduct research at the station. Its facilities are available for graduate and postdoctoral research with the approval of the director. People interested in the field station may contact the director via the Department of Integrative Biology.

The Gump South Pacific Research Station, French Polynesia, is located on Moorea (17° 30' S 149° 50' W), one of the Society Islands, 15 km northwest of the main island of Tahiti. Moorea offers diverse habitats ranging from coral reefs, lagoons, coastal beaches, freshwater streams, wetlands, and mountain forests. The Gump Station occupies 14 hectares (35 acres) of land from the shore to 149m (489ft) at the entrance to Cook's Bay, providing excellent access to the ocean, lagoon, and island interior. A range of housing options (shared dormitories, private bungalows) and laboratories allow long- and short-term research and education in a diversity of fields, including marine, freshwater, and terrestrial biology, evolutionary and conservation biology, archaeology, anthropology, ethnobotany, geology, and geomorphology. Facilities include boats and 4WD vehicles. A waterfront marine laboratory contains an open seawater system and equipment for UC Scientific Diving. A large climate controlled research building contains offices, library/conference room, and several laboratories including space for morphological work (high-quality microscopes) and molecular genetic analyses. The Station is connected to the Internet via multiple ADSL lines and has WIFI access in all common areas. For further information, contact Dr. Neil Davies, Executive Director,ndavies@moorea.berkeley.edu . More information can be found on the station website.

The Human Evolution Research Center (HERC) is dedicated to the study of human origins and evolution. HERC represents an international focal point for field and laboratory research and education. It is a center for the study of the process and products of human evolution. Research by the HERC includes both field and laboratory investigation. The center’s collections and facilities provide support to faculty and students working on important, large-scale investigations. These include The Middle Awash Project and The Revealing Hominid Origins Initiative (RHOI). For more information on HERC and RHOI, see the HERC website  and the RHOI website,  respectively.

The Jane Gray Research Greenhouse is operated by the Department of Integrative Biology and comprises approximately 2,400 square feet of state-of-the-art research space, used for projects by faculty and students. The climate management system is computer-controlled and monitors temperature, humidity, light energy, and wind speed and direction. The system’s responses to these conditions can be controlled centrally or from a remote location through an on-screen ARGUS interface to gas heaters, evaporative coolers, vents, fans, and sunshades. The facility provides an ideal resource for plant growth investigations that require closely controlled and monitored conditions. For more information, see the Greenhouse website.

The Museum of Paleontology (UCMP), a research institute for faculty, staff, students, and qualified visiting scholars, has one of the largest collections of fossil protists, invertebrates, plants, and vertebrates in the nation, as well as large collections of modern vertebrate skeletal elements and invertebrates. The collection is worldwide in scope and is especially strong in materials from western North America. Research activities include systematic, paleobiogeographic, paleoecologic, biostratigraphic, evolutionary, and theoretical paleobiologic studies. Field work on all continents by researchers and students associated with the museum continues to sustain substantial collection growth. Special facilities include molecular biology and fossil preparation laboratories, as well as specialized laboratories for microfossils, pollen, and cast production.

UCMP has an active education and outreach program, using the web as its primary venue for sharing science with a broader audience. The UCMP website  contains a wealth of information on evolution, paleontology, systematics, and associated sciences, as well as access to collections data and specimen images. Requests for use of the collections or facilities should be mailed to the Director, Museum of Paleontology, Valley Life Sciences Building, University of California, Berkeley; Berkeley, CA 94720.

The Museum of Vertebrate Zoology is an Organized Research Unit affiliated with the Department of Integrative Biology and the Berkeley Natural History Museums. It was established in 1908 and has grown to be one of the largest and most important collections of amphibians, reptiles, birds, and mammals in the world. The museum has no public exhibits; it is primarily a research organization and a center for graduate and postdoctoral education. The museum's space in the Valley Life Sciences Building includes all of the collections as well as administrative and research offices for faculty, postdoctoral, and graduate students. In addition, there are laboratories for molecular genetics and biodiversity informatics. Research activities center on problems in evolutionary biology, with emphasis on systematics, ecology, functional and developmental morphology, behavior, population and conservation biology, and biogeography. Integration of field and laboratory methods is encouraged. For more information, write to the Director, Museum of Vertebrate Zoology, UC Berkeley; Berkeley, CA 94720, or, for the Hastings Reservation, to Dr. Mark Stromberg, Carmel Valley, CA 93925. More information can be found on the museum's website.

The University and Jepson Herbaria offer a worldwide reference-research collection, laboratories, archive, and library that form a foundation for basic research in systematic botany, ecology, phytogeography, evolution, and comparative genomics. These resources are available not only to faculty, staff, and students but also to visiting scholars and biologists throughout the United States and other countries. Resources include:

  1. The collection itself, more than 2.2 million specimens with special strengths in the angiosperm flora of California and elsewhere around the Pacific Rim, as well as in cryptogamic groups including ferns, bryophytes, fungi, and algae.
  2. Modern laboratories for all types of plant studies, ranging from morphology/anatomy to molecular systematics. 
  3. Extensive electronic resources, including an online flora of California, and interface for accessing electronic records from all California herbaria, the world's standard index of algal nomenclature, to the tree of life for green plants.

See the website  at for more information. Inquiries should be addressed to: Director, University and Jepson Herbaria, University of California, Berkeley; Berkeley, CA 94720.

The University of California Natural Reserve System (NRS) was founded in 1965 to establish and maintain significant examples of California's diverse aquatic and terrestrial ecosystems for university-level teaching, research, and public service. The 33 reserves are open to all qualified individuals and institutions for scholarly work in disciplines ranging from geology and environmental sciences to anthropology and art. For more information on the NRS, contact the UC Office of the President at (510) 987-0150 or go to the UC Office of the President website.  For specific information regarding the four reserves administered by the Berkeley campus, contact faculty reserve manager Mary Power at (510) 643-7776 or mepower@berkeley.edu . The Berkeley campus administers these four reserves:

  • The Angelo Coast Reserve in Mendocino County is one of the most diverse reserves, with 26 terrestrial and four aquatic habitat types. Located along a belt of highly deformed, well-defined coastal ridges cut by the South Fork of the Eel River, the reserve contains the largest virgin Douglas fir community left in the state, as well as four undisturbed watersheds. It is part of the UNESCO California Coast Ranges Biosphere Reserve. For more information, contact Peter Steel at (707) 984-6653 or psteel@nature.berkeley.edu .
  • The Chickering American River Reserve in Placer County is located in the sub-alpine headwaters basin of the North Fork of the American River. The reserve has diverse topography, soil, and moisture regimes on sedimentary, igneous, and metamorphic substrates. It supports approximately 1,000 plant species, unusual red fir and mixed-conifer old-growth forest communities, and a variety of large mammals. Long-term research continues on the endangered wolverine. For more information, contact James Kirchner at (510) 643-8559 or kirchner@geomorph.berkeley.edu .
  • The Hans Jenny Pygmy Forest Reserve in Mendocino County supports elfin forests of endemic pygmy cypress, bishop pine, and unusual evergreen shrub species on highly podsolized, old marine terrace soils. This reserve is adjacent to lands managed by The Nature Conservancy. For more information, contact Ronald G. Amundson at (510) 643-7890 or earthy@nature.berkeley.edu.
  • The Hastings Natural History Reserve in Monterey County contains a representative sample of California's interior Coast Range ecosystem, with annual and perennial grasslands, oak woodlands, chaparral, and running streams. The reserve has 620 vascular plant species and 166 bird species. While noted for its 50-year research history on vertebrate ecology and oak woodland biology, the reserve is also conducting important research on native grassland restoration. For more information, contact Mark Stromberg at (831) 659-2664 or stromber@berkeley.edu.  

INTEGBI C13/ASTRON C13 Origins: from the Big Bang to the Emergence of Humans 4 Units

Department: Integrative Biology; Astronomy

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 2 hours of Discussion per week for 15 weeks.

This course will cover our modern scientific understanding of origins, from the Big Bang to the formation of planets like Earth, evolution by natural selection, the genetic basis of evolution, and the emergence of humans. These ideas are of great intrinsic scientific importance and also have far reaching implications for other aspects of people's lives (e.g., philosophical, religious, and political). A major theme will be the scientific method and how we know what we know.

Instructors: Marshall, Quataert

INTEGBI 24 Freshman Seminars 1 Unit

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: The grading option will be decided by the instructor when the class is offered.

Hours and format: 1 hour of Seminar per week for 15 weeks.

The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

Course may be repeated for credit as topic varies. Course may be repeated for credit when topic changes.

INTEGBI 31 The Ecology and Evolution of Animal Behavior 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of lecture, 1 hour of film/demonstration and 1 hour of discussion per week.

Prerequisites: Open to all students; designed for those not specializing in biology.

Principles of evolution biology as they relate to animal behavior and behavioral ecology with broad coverage of animal groups. Special attention will be paid to the emerging discipline of behavioral ecology.

Students will receive no credit for Integrative Biology 31 after taking Integrative Biology 144, C144 or Psychology C115B. Instructor: Caldwell

INTEGBI N33 Topics in Paleontology: The Age of Dinosaurs 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 4 hours of Lecture per week for 8 weeks.

Open without prerequisite to all students and designed for those not specializing in paleontology. Evolution history, and ecology of the dinosaurs and their world, including the earliest mammals and birds.

More than one course in this series may be taken for credit with consent of instructor. Course may be repeated for credit when topic changes.

INTEGBI 35AC Human Biological Variation 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week.

This course addresses modern human biological variation from historical, comparative, evolutionary, biomedical, and cultural perspectives. It is designed to introduce students to the fundamentals of comparative biology, evolutionary theory, and genetics.

Satisfies the American Cultures requirement

Instructor: Hlusko

INTEGBI 37 Topics in Paleontology: The Antecedents of Man 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 3 hours of lecture and 2 hours of laboratory/discussion per week.

. Open without prerequisite toall students and designed for those not specializing in paleontology. Survey the evolution, ecology, and history of the primate order. Special emphasis will be given to primate origins, geographic distribution, and the evolution of the human lineage.

INTEGBI 39C Topics in Integrative Biology 2 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Offered for pass/not pass grade only.

Hours and format: 2 hours of Discussion per week for 15 weeks.

Prerequisites: Preferentially open to freshmen; consent of instructor.

Reading and discussion of the literature on particular topics in the field of integrative biology. Term paper and oral presentation. Section topics will vary from semester to semester. Students should check with department secretary for each semester's offerings.

INTEGBI 41 Marine Mammals 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of Lecture per week for 15 weeks. 4 hours of Lecture per week for 8 weeks. 5.5 hours of Lecture per week for 6 weeks.

Prerequisites: Designed for those not specializing in Integrative Biology.

A survey of marine mammal evolution, biology, behavior, ecology, and politics with a concentration on those species found in the North Pacific. Coverage would include: origin and evolution of cetaceans, pinnipeds, sirenians, and sea otters; basic biology and anatomy of marine mammal groups, and North Pacific species in particular; ecological interactions and role in nearshore and pelagic marine communities; and interactions between humans and marine mammals.

Instructor: Lindberg

INTEGBI 42 Primate Biology 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 6 hours of Lecture per week for 8 weeks.

An introduction to the order of mammals of which we are members. The niches of primates in modern ecosystems, their anatomical and behavorial specialization, and their role as indicator species in conservation. The mechanisms and variety of primate social organization compared with that of other animals.

Open to all students but designed for those not specializing in biology.

INTEGBI C82/EPS C82/GEOG C82 Oceans 3 Units

Department: Integrative Biology; Earth and Planetary Science; Geography

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks. 3.5 hours of Lecture per week for 8 weeks. 5 hours of Lecture per week for 6 weeks.

This course offers multidisciplinary approach to begin answering the question "Why are oceans important to us?" Upon a physical, chemical, and geologic base, we introduce the alien world of sea life, the importance of the ocean to the global carbon cycle, and the principles of ecology with a focus on the important concept of energy flow through food webs. Lectures expand beyond science to include current topics as diverse as music, movies, mythology, biomechanics, policy, and trade.

INTEGBI 84 Sophomore Seminar 1 or 2 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: The grading option will be decided by the instructor when the class is offered.

Hours and format: 1 hour of seminar per week per unit for 15 weeks. 1 and 1 half hours of seminar per week per unit for 10 weeks. 2 hours of seminar per week per unit for 8 weeks. 3 hours of seminar per week per unit for 5 weeks.

Prerequisites: At discretion of instructor.

Sophomore seminars are small interactive courses offered by faculty members in departments all across the campus. Sophomore seminars offer opportunity for close, regular intellectual contact between faculty members and students in the crucial second year. The topics vary from department to department and semester to semester. Enrollment limited to 15 sophomores.

Course may be repeated for credit as topic varies. Course may be repeated for credit when topic changes.

INTEGBI 87 Introduction to Research Methods in Biology 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 1 hour of Lecture, 1 hour of Discussion, and 3 hours of Laboratory per week for 8 weeks.

Prerequisites: Consent of instructor.

This course provides a functional understanding of hypothesis/data driven research and exposure to current approaches and methods in biological science. The lectures address foundational concepts of the scientific method, research ethics, scientific communication, and how to understand scientific literature. The labs provide exposure to faculty research and experimental methods. The course is geared to incoming freshmen, sophomores, and transfer students interested in learning more about research.

Instructor: Matsui

INTEGBI 88 Leadership Communications for Biology Scholars 1 Unit

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of lecture/discussion per week.

Prerequisites: Acceptance into Biology Scholars Program.

Leadership skills and abilities such as communication, collaboration, critical thinking, and resourcefulness are critical to academic, professional, and personal success. The need for enlightened leaders is evident in every aspect of health and science such as designing innovative health programs, obtaining funding, conducting cutting-edge research, developing and gaining support to implement policy solutions. This course provides an understanding of the principles of leadership and communications for students in the Biology Scholars Program. Students wil nurture those traits in themselves and apply those principles in situations specifically related to the health and science sectors. The course is taught in weekly lecture and discussion sessions with case studies and exercises. The specific objectives of this course are to identify leadership principles; understand one's own leadership style and goals; know what resourcefulness means and the strategies that can enhance it; develop skills in written and verbal communication, and develop skills in collaboration and effective team management.

Instructors: Hayes, Kim, Myrick

INTEGBI 95 Special Research Project in Biology 1B 1 Unit

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: 6 hours of special field research per week for 8 weeks. 4 hours of special field research per week.

Prerequisites: Consent of instructor; selected by interview.

Students enrolled in BIOLOGY 1B can participate in special field research in addition to attending regular laboratory sections. Students work independently with minimal supervision. Students will learn how to develop a project, collect and record data, conduct and analyze experiments, write a report, and make an oral presentation. Project may require traveling to off-campus sites. Students are required to attend at least three department seminars and write a short critique of each.

INTEGBI C96/MCELLBI C96/PLANTBI C96 Studying the Biological Sciences 1 Unit

Department: Integrative Biology; Molecular and Cell Biology; Plant and Microbial Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Offered for pass/not pass grade only.

Hours and format: 2 hours of Lecture per week for 15 weeks.

Prerequisites: Consent of instructor.

Freshmen will be introduced to the "culture" of the biological sciences, along with an in-depth orientation to the academic life and the culture of the university as they relate to majoring in biology. Students will learn concepts, skills, and information that they can use in their major course, and as future science professionals. Restricted to freshmen in the biology scholars program.

Instructor: Matsui

INTEGBI 98 Directed Group Study 1 - 4 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: 1 hour of group study per unit per week.

Prerequisites: Freshmen and sophomores only.

Lectures and small group discussions focusing on topics of interest, varying from semester to semester.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 99 Supervised Independent Study and Research 1 - 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: Zero hours of Independent study per week for 15 weeks. 1 to 3 hour of Independent study per week for 8 weeks. 1 to 3 hour of Independent study per week for 6 weeks.

Prerequisites: GPA of 3.4 or greater.

Lower division independent study and research intended for the academically superior student. Enrollment only with prior approval of faculty adviser directing the research.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Formerly known as Botany 99, Physiology 99, Anatomy 99.

INTEGBI 100B Principles of Biodiversity 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week, plus some assigned open computer laboratories.

Prerequisites: Biology 1B.

Biogeographic, temporal, and historical patterns of change in biological diversity; phylogenetics and systematics; processes involved in origin and extinction of taxa and floras/faunas; population structure and demography (including human populations); community processes and maintenance of diversity; ecosystem function; global change; human uses of and effects on biodiversity; conservation biology.

INTEGBI C100/EPS C100/GEOG C146 Communicating Ocean Science 4 Units

Department: Integrative Biology; Earth and Planetary Science; Geography

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2.5 hours of Lecture, 1 hour of Discussion, and 2 hours of Fieldwork per week for 15 weeks.

Prerequisites: One course in introductory biology, geology, chemistry, physics, or marine science required and interest in ocean science; junior, senior, or graduate standing; consent of instructor required for sophomores.

For undergraduates interested in improving their ability to communicate their scientific knowledge by teaching ocean science in elementary schools or science centers/aquariums. The course will combine instruction in inquiry-based teaching methods and learning pedagogy with six weeks of supervised teaching experience in a local school classroom or the Lawrence Hall of Science with a partner. Thus, students will practice communicating scientific knowledge and receive mentoring on how to improve their presentations.

Instructor: Ingram

INTEGBI 102LF Introduction to California Plant Life with Laboratory 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of lecture and 6 hours of laboratory per week.

Prerequisites: Biology 1B or consent of instructor.

The relationship of the main plant groups and the plant communities of California to climate, soils, vegetation, geological and recent histor,y and conservation. Laboratory will also include at least two Saturday field trips and focus on main plant groups and major plant families in California, and use of keys to identify introduced and especially native pteridophytes, conifers, and flowering plants of the state.

Student will receive partial credit for 102LF after taking 102. Formerly known as 102L.

INTEGBI 103LF Invertebrate Zoology with Laboratory 5 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 3 hours of lecture and 6 hours of laboratory per week, plus several weekend field trips.

Prerequisites: Biology 1A-1B.

Introductory survey of the biology of invertebrates, stressing comparative functional morphology, phylogeny, natural history, and aspects of physiology and development. Laboratory study of invertebrate diversity and functional morphology, and field study of the natural history of local marine invertebrates.

Students will receive partial credit for 103LF after taking 103. Formerly known as 103L. Instructor: Lindberg

INTEGBI 104LF Natural History of the Vertebrates with Laboratory 5 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of lecture, 3 hours of laboratory, and a 4 hour field trip per week, plus special field projects.

Prerequisites: Biology 1A-1B.

Biology of the vertebrates, exclusive of fish. Laboratory and field study of local vertebrates exclusive of fish.

Students will receive partial credit for 104LF after taking 104. Instructors: McGuire, Bowie, Shabel

INTEGBI C105/ESPM C105 Natural History Museums and Biodiversity Science 3 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of lecture and 3 hours of laboratory per week.

(1) survey of museum resources, including strategies for accession, conservation, collecting and acquiring material, administration, and policies; (2) strategies for making collections digitally available (digitization, databasing, georeferencing, mapping); (3) tools and approaches for examining historical specimens (genomics, isotopes, ecology, morphology, etc); and (4) data integration and inference. The final third of the course will involve individual projects within a given museum.

Instructors: Gillespie, Mishler, Will, Marshall, McGuire

INTEGBI 106A Physical and Chemical Environment of the Ocean 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1B; Chemistry 1A or 4A; Mathematics 1A or 16A; Physics 7A or 8A. Recommended: 82.

The biological implications of marine physics and chemistry. History and properties of seawater. Geophysical fluids. Currents and circulations. Deep sea. Waves, tides, and bottom boundary layers. The coastal ocean; estuaries. Air/sea interaction. Mixing. Formation of water masses. Modeling biological and geochemical processes. Ocean and climate change.

Instructor: Powell

INTEGBI C107L/PLANTBI C107L Principles of Plant Morphology with Laboratory 3 Units

Department: Integrative Biology; Plant and Microbial Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 1 hour of lecture and 3 hours of laboratory and 1 hour of discussion per week.

Prerequisites: Biology 1A-1B.

An analysis of the structural diversity of land plants plants with emphasis on the developmental mechanisms responsible for this variation in morphology and the significance of this diversity in relation to adaptation and evolution.

Instructor: Specht

INTEGBI C110L/PLANTBI C110L Biology of Fungi with Laboratory 4 Units

Department: Integrative Biology; Plant and Microbial Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of lecture and 6 hours of laboratory per week. Several field trips are offered, including day trips to a mushroom farm and winery, and a weekend mushroom foray.

Prerequisites: Biology 1B

Selected aspects of fungi: their structure, reproduction, physiology, ecology, genetics and evolution; their role in plant disease, human welfare, and industry. Offered even fall semesters.

Instructors: Bruns, Taylor

INTEGBI 112 Horticultural Methods in the Botanical Garden 1 Unit

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Offered for pass/not pass grade only.

Hours and format: 3 hours of direct participation of field work per week.

Prerequisites: Consent of instructor.

An introduction to horticultural techniques utilizing the diverse collections of the University Botanical Garden.

Formerly known as 112L. Instructor: Licht

INTEGBI 113L Paleobiological Perspectives on Ecology and Evolution 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

Prerequisites: Prior biology experience, or consent of instructor. No paleontological or geological background required.

This course will center around answering the following questions: What do the fossil and geologic records have to tell us about the nature of ecological and evolutionary processes? What do they teach us that cannot be learned from the living world alone? In answering these questions, the course will provide an introduction to the analysis of key problems in paleobiology, with an emphasis on how evolutionary and ecological processes operate on geologic timescales.

Formerly known as 108. Instructor: Marshall

INTEGBI 115 Introduction to Systems in Biology and Medicine 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of lecture and 2 hours of computer laboratory per week.

Prerequisites: Biology 1A, Mathematics 1A or 16B.

This course is aimed at students wishing to understand the general principles of how biological systems operate. Topics include feedback regulation; competition and cooperation; genetic switches and circuits; random processes; chaos; mechanisms for error correction; and the properties of networks. Examples are selected from many fields including medicine, physiology, ecology, biochemistry, cell biology, and genetics. Students will learn to conceptualize and quantify interactions within biological systems using simple mathematical models and computer programs. No previous experience in programming is required.

Instructor: Lim

INTEGBI 116L Medical Parasitology 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 6 hours of Lecture and 6 hours of Laboratory per week for 6 weeks.

Prerequisites: 1A, 1B, or equivalent.

This course includes the biology, epidemiology, pathogenesis, treatment, and prevention of various medically important parasitic infections. Life cycles of parasitic helminths and protozoa, the biological aspects of the host-parasite relationship, the epidemiology of the infection, and the interplay of social, economical, and ecological factors which contribute to the disease will be covered in both lectures and videos.

Formerly known as 116. Instructor: Sakanari

INTEGBI 117 Medical Ethnobotany 2 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and summer

Grading: Letter grade.

Hours and format: 2 hours of Lecture per week for 15 weeks. 5 hours of Lecture per week for 6 weeks.

Biological diversity and ethno-linguistic diversity sustain traditional botanical medicine systems of the world. Major topics covered in this course include cultural origins of medicinal plant knowledge on plant-derived pharmaceuticals and phytomedicines; field research methods in ethnobotany and ethnopharmacology; examples of how traditional botanical medicines provide safe, effective, affordable, and sustainable primary health care to tropical countries; human physiology, human diseases, and mechanisms of action of plant-derived drugs.

Instructor: Carlson

INTEGBI 117LF Medical Ethnobotany Laboratory 2 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and summer

Grading: Letter grade.

Hours and format: 8 hours of field laboratory per day for 4 Saturdays. 8 hours of field laboratory per day for 4 Saturdays.

Laboratory will focus on studying medicinal plants from the major ecosystems and geographical regions of the world. Students will learn common names, scientific names, plant families, field identification, habitats, and ethnomedical uses of medicinal plants. How the medicinal plant is prepared, administered, and used as a phytomedicine will also be discussed. There will be reference to the phylogenetic relationships between the plant families and genera represented by the medicinal plants.

Formerly known as 117L. Instructor: Carlson

INTEGBI 118 Host-Pathogen Interactions: A Trans-Discipline Outlook 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week.

Prerequisites: Biology 1A-1B.

The second half of the 20th century is marked by great strides in the battle against infectious diseases. However, the forces that drive pathogen evolution continue to pose new challenges for science and medicine. In this course we will cover various aspects relating to host-pathogen interactions, focusing on animals and their bacterial pathogens. We will address the ecology of host-pathogen interactions, their shaping by co-evolution, examine prominent molecular mechanisms taking part in this warfare and learn how ancient mechanisms are used and reused through millions of years of evolution. The course will examine how better understanding of host-pathogen interactions can suggest new strategies for fighting infectious diseases.

Instructor: Shapira

INTEGBI 119 Evaluating Scientific Evidence in Medicine 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of lecture, 1 computer laboratory, and 1 discussion per week.

Prerequisites: Biology 1A-1B.

A course in critical analysis of medical reports and studies using recent controversial topics in medicine. Course will focus on information gathering, hypothesis testing, evaluating study design, methodological problems, mechanisms of bias, interpretation of results, statistics, and attribution of causation. Students participate in a mock trial as a way to demonstrate their abilities to gather, critically analyze, and present scientific and medical evidence.

Instructor: G. Caldwell

INTEGBI 123AL Exercise Physiology with Laboratory 5 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

Prerequisites: Biology 1A, Chemistry 3B and Integrative Biology 132 or Molecular and Cell Biology 136.

Discussion of how chemical energy is captured within cells and how potential chemical energy is converted to muscular work. Energetics, direct and indirect calorimetry, pathways of carbon flow in exercise, ventilation, circulation, skeletal muscle fiber types. Laboratory component of the course is to obtain practical experience in the measurement of physiological parameters and to be able to compile, compare, contrast, and interpret physiological data. Laboratory demonstrations and exercises will explain lecture content.

Student will receive partial credit for 123AL after taking 123A. Instructor: Brooks

INTEGBI C125L/PHYS ED C165 Introduction to the Biomechanical Analysis of Human Movement 4 Units

Department: Integrative Biology; Physical Education

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

Prerequisites: 9 and Integrative Biology 131 and 131L.

Basic biomechanical and anatomical concepts of human movement and their application to fundamental movement patterns, exercise, and sport skills.

Instructor: Scott

INTEGBI 127L Motor Control with Laboratory 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 2 hours of Laboratory per week for 15 weeks.

Prerequisites: 132 or Molecular and Cell Biology 136.

Neural control of movement in humans and other animals. Lectures introduce basic theories of information and control, analyze motor control at the spinal level, survey anatomy and physiology of motor systems of the brain, and synthesize theory and physiology to understand control systems that regulate posture, locomotion, and voluntary movements. In laboratories, students learn theory and motor physiology hands-on, and design and perform independent investigations.

Students will receive partial credit for 127L after taking 127. Instructor: Lehman

INTEGBI C129L/PHYS ED C129 Human Physiological Assessment 3 Units

Department: Integrative Biology; Physical Education

Course level: Undergraduate

Terms course may be offered: Spring and summer

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 3 hours of Laboratory per week for 15 weeks. 5 hours of Lecture and 7.5 hours of Laboratory per week for 6 weeks.

Prerequisites: Biology 1A, IB 132 (may be taken concurrently); IB 123AL is recommended.

Principles and theories of human physiological assessment in relation to physical activity and conditioning. Performance of laboratory procedures in the measurement and interpretation of physiological fitness (cardiorespiratory endurance, body composition, musculoskeletal fitness).

Instructor: Johannessen

INTEGBI 130 Human Fertility - The Big History of our Species' Reproductive Journey 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of lecture and 2 hours of laboratory per week.

This course explores human reproduction through the lenses of evolutionary biology, population statistics, and culture. Throughout, we organize the course in terms of major transitions and the question of choice. How do evolved biology and inherited culture make some choices more accessible and others less so? What happened to human fertility—and to the possibility of making choices about fertility—at such moments of change as the emergence of pair bonding in hominids, the advent of agriculture, the industrial revolution, and the development of both contraceptive and proceptive technologies in the 20th consequences do these histories on different time-scales have for young people today contemplating their own reproductive choices?

Instructors: Hlusko, Johnson-Hanks

INTEGBI C130/SOCIOL C118 Human Fertility 4 Units

Department: Integrative Biology; Sociology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture and 2 hours of laboratory per week.

This course explores human reproduction through the lenses of evolutionary biology, population statistics, and culture. Throughout, we organize the course in terms of major transitions and the question of choice. How do evolved biology and inherited culture make some choices more accessible and others less so? What happened to human fertility—and to the possibility of making choices about fertility—at such moments of change as the emergence of pair bonding in hominids, the advent of agriculture, the industrial revolution, and today with the development of both contraceptive and prospective technologies.


Instructors: Hlusko, Johnson-Hanks

INTEGBI 131 General Human Anatomy 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks. 6 hours of Lecture per week for 8 weeks. 8 hours of Lecture per week for 6 weeks.

Prerequisites: Biology 1A-1B or Chemistry 1A.

The functional anatomy of the human body as revealed by gross and microscopic examination. Designed to be taken concurrently with 131L.

Instructor: Carlson

INTEGBI 131A Applied Anatomy 1 Unit

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Offered for pass/not pass grade only.

Hours and format: 1 hour of lecture per week.

A series of 15 lectures by former students of 131 who have become successful physicians and surgeons. The purpose is to provide the practical applications of anatomy, e.g., plastic surgeons, neurosurgeons, vascular surgeons, pathologists, etc.

Course may be repeated once for credit.Course may be repeated for a maximum of 2 units. Instructor: Diamond

INTEGBI 131L General Human Anatomy Laboratory 2 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and summer

Grading: Letter grade.

Hours and format: 4 hours of Laboratory per week for 15 weeks. 8 hours of Laboratory per week for 8 weeks. 10 hours of Laboratory per week for 6 weeks.

Prerequisites: Biology 1A-1B or Chemistry 1A. 131 (may be taken concurrently).

Prepared human dissections, models, and microscopic slides.

Instructor: Carlson

INTEGBI S131 General Human Anatomy 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 6 hours of Lecture per week for 8 weeks.

Prerequisites: A college of course in biology or chemistry.

The functional anatomy of the human body as revealed by gross and microscopic examination.

INTEGBI 132 Survey of Human Physiology 4 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Spring and summer

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week. 6 hours of lecture and 2 hours of discussion per week for 8 weeks.

Prerequisites: 131, Biology 1A.

Mechanisms by which key physiological priorities are maintained in healthy humans. From a basis in elementary theories of information and control, we develop an understanding of homeostasis of cellular composition, structure, and energy metabolism. We then study neural and endocrine signaling in humans, and develop the key concepts of control and homeostasis in all the major organ and multi-organ systems, including cardiovascular, respiratory, renal, metabolic, reproductive, and immune systems, growth and development, and sensory and motor systems.

Students will receive no credit for 132 after taking Physiology 100 or 101 or Molecular and Cell Biology 32, 136. Instructors: Brooks, Kaufer, Lehman

INTEGBI 132L Mammalian Physiology Laboratory 2 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Spring and summer

Grading: Letter grade.

Hours and format: 3 hours of Laboratory per week for 15 weeks. 6 hours of Laboratory per week for 8 weeks.

Prerequisites: Previous or concurrent enrollment in 132 or equivalent, or consent of instructor.

In the laboratory component of Integrative Biology 132, students gain hands-on experience measuring physiological parameters, interpreting physiological data, designing experiments, and communicating ideas in writing and orally. Guided investigations include measurements of membrane potentials, responses of skeletal muscle to electrical stimulation, electromyography, pulmonary and cardiovascular measurements in humans, contractility and regulation of the frog heart, human electrocardiography, and renal control of body fluids. In two independent investigations, students identify their own questions, develop hypotheses, design and perform experiments, and present their studies in symposia. Background in elementary statistics, data analysis and oral presentation are also provided.

Students will receive no credit for 132L after taking Molecular and Cell Biology 32L or 136L, or if currently enrolled in similar courses. Instructors: Brooks, Kaufer, Lehman

INTEGBI 133 Anatomy Enrichment Program 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Offered for pass/not pass grade only.

Hours and format: Fieldwork--minimum of 4 hours per week arranged.

Prerequisites: 131 with a grade of A or B.

The purpose of the course is for University students to teach human anatomy to grades K-7 in the public schools. The UCB students work in groups of 2-3 to plan their presentations of the systems of the body and then enter the school rooms to teach what they have learned in 131.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Diamond

INTEGBI 135 The Mechanics of Organisms 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall. Offered alternate years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Introductory physics and biology recommended.

Organism design in terms of mechanical principles; basics of fluid and solid mechanics with examples of their biological implications, stressing the dependence of mechanical behavior and locomotion on the structure of molecules, tissues, structural elements, whole organisms, and habitats.

Instructors: Dudley, Full, Koehl

INTEGBI C135L/BIO ENG C136L/EL ENG C145O Laboratory in the Mechanics of Organisms 3 Units

Department: Integrative Biology; Bioengineering; Electrical Engineering

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 6 hours of laboratory and 1 hour of discussion per week, plus 1 field trip.

Prerequisites: Integrative Biology 135 or consent of instructor; for Electrical Engineering and Computer Science students, Electrical Engineering 105, 120 or Computer Science 184.

Introduction to laboratory and field study of the biomechanics of animals and plants using fundamental biomechanical techniques and equipment. Course has a series of rotations involving students in experiments demonstrating how solid and fluid mechanics can be used to discover the way in which diverse organisms move and interact with their physical environment. The laboratories emphasize sampling methodology, experimental design, and statistical interpretation of results. Latter third of course devoted to independent research projects. Written reports and class presentation of project results are required.

Students will receive no credit for C135L after taking 135L. Formerly known as Integrative Biology 135L.

INTEGBI 136 The Biology of Sex 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: The course consists of 3 hours of lectures and 2 hours of computer exercises and/or discussion each week.

Prerequisites: Biology 1B, introductory genetics (Mendelian genetics, recombination, chromosomes).

The ability to reproduce is a defining characteristic of life, and of great interest to biologists as well as humanity in general. What is sex, and why did it develop? Why do we have sexual reproduction, whereas some animals do not? This course will provide a comprehensive overview on the biology of sex from an evolutionary perspective with an emphasis on humans in comparison to other species. The course will consist of two lectures each week, and a lab where we discuss a paper, watch videos, or have discussion sections on specific topics that were covered in class.

Instructor: Bachtrog

INTEGBI 137 Human Endocrinology 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1A-1B; human physiology (132) strongly recommended.

Course will address the role of hormones in physiology with a focus on humans. Regulation of hormone secretion and mechanisms of hormone action will be discussed. Physiological processes to be addressed include reproduction, metabolism, water balance, growth, fetal development. Experimental and clinical aspects will be addressed.

Instructor: Hayes

INTEGBI 138 Comparative Endocrinology 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1A-1B. Organic Chemistry recommended.

The primary goal of this course is to provide students with a broad understanding of the evolution of hormonal systems. A comparative approach allows us to envisage how the complex mammalian endocrine system presumably evolved from that of more primitive vertebrates. Students will learn about endocrine pathways and endocrine-based behaviors of jawless fishes, fishes, amphibia, reptiles, birds, and mammals. In addition, students will gain an understanding of the experimental methods used in endocrine research. The class teaches students how to read and interpret the primary scientific literature; thus it encourages the critical thinking that is a fundamental skill for any scientist.

Instructor: Bentley

INTEGBI 139 The Neurobiology of Stress 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week.

Prerequisites: Biology 1A or Psychology 110. You will need a good understanding of the fundamentals of biology to do well in this class.

This course is designed to be an interdisciplinary course. It will adopt a broad-based approach to explore the concepts of stress, health, and disease, with a particular focus on current primary literature. The course will cover multiple dimensions in the study of stress, which employ genetic, epigenetic, molecular, cellular, physiological, and cognitive approaches, especially in the context of endocrine and neuroscience research. We will analyze the individual response to stress, how genetic and environmental factors play a role in it, how it translates to physiological and mental health and well-being vs. pathological conditions, and put that in a public health perspective.

Course Objectives: This course will emphasize the interconnected and multidirectional relationships between biology, behavior and the social environment. The study of stress is necessarily an interdisciplinary endeavor. This course is designed to explore the role of genes, hormones and experiences as they affect the stress-response and subsequently brain and behavior.

Instructor: Kaufer

INTEGBI 140 Biology of Human Reproduction 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks. 6 hours of Lecture and 2 hours of Discussion per week for 8 weeks.

Prerequisites: Biology 1A or equivalent.

Course focuses on biological and cultural aspects of human reproduction including conception, embryology, pregnancy, labor, delivery, lactation, infant/child development, puberty, and reproductive aging. This includes study of factors that diminish and factors that enhance fertility, reproduction, and maternal-child health. We explore evolutionary, ecological, environmental, cultural, ethnobiological, and nutritional determinants of fertility, reproductive rate, infant survival, and population growth.

Instructor: Carlson

INTEGBI 141 Human Genetics 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 6 hours of Lecture per week for 8 weeks.

Prerequisites: One course in biological science.

Principles of inheritance, especially as applied to human traits, including molecular aspects of genetics, the genetic constitutions of populations, and questions of heredity/environment.

Students will receive no credit for 141 after taking Molecular and Cell Biology 142 or C142 and Integrative Biology C163.

INTEGBI C142L/ANTHRO C103 Introduction to Human Osteology 6 Units

Department: Integrative Biology; Anthropology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 6 hours of Lecture and 14 hours of Laboratory per week for 15 weeks.

Prerequisites: Anthropology 1, Biology 1B.

An intensive study of the human skeleton, reconstruction of individual and population characteristics, emphasizing methodology and analysis of human populations from archaeological and paleontological contexts, taphonomy, and paleopathology.

Instructor: White

INTEGBI C143A/PSYCH C113 Biological Clocks: Physiology and Behavior 3 Units

Department: Integrative Biology; Psychology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Completion of biological prerequisites for the major and one of the following: 110 or a course in animal organismal physiology (Integrative Biology 132, 138, 140, 148, or Molecular and Cell Biology 160).

A consideration of the biological clocks that generate daily, lunar, seasonal and annual rhythms in various animals including people. Emphasis on neuroendocrine substrates, development and adaptive significance of estrous cycles, feeding rhythms, sleep-wakefulness cycles, reproductive and hibernation cycles, body weight and migratory cycles.

INTEGBI C143B/PSYCH C116 Hormones and Behavior 3 Units

Department: Integrative Biology; Psychology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Completion of biological prerequisites for the major and consent of instructor; a course in mammalian physiology recommended.

This course provides a comprehensive overview of behavorial endocrinology beginning with hormone production and actions on target issues and continuing with an exploration of a variety of behaviors and their hormonal regulation/consequences. The course uses a comparative approach to examine the reciprocal interactions between the neuroendocrine system and behavior, considering the effects of hormone on development and adult behavior in addition to how behavior regulates endocrine physiology. While much of the course focuses on non-human vertebrate species, the relevance to humans is explored where appropriate. Topics include sexual differentiation and sex differences in behavior, reproductive, parental, and aggressive behaviors, and hormonal and behavioral homeostatic regulation.

INTEGBI C144/ESPM C126 Animal Behavior 4 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week.

Prerequisites: Biology 1A, 1B, or Environmental Science, Policy, and Management 140. Molecular and Cell Biology 140 and C160 recommended.

An introduction to comparative animal behavior and behavioral physiology in an evolutionary context, including but not limited to analysis of behavior, genetics and development, learning, aggression, reproduction, adaptiveness, and physiological substrates.

Students will receive no credit for 144 after taking C144, 145, 146LF, or Psychology C115B. Instructors: Lacey, Caldwell, Bentley, Elias

INTEGBI 146 Behavioral Ecology 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 2 hours of lecture and 1 hour of discussion per week. In addition, students will be required to at10d 2 afternoon and 1 overnight field trips.

Prerequisites: C144.

An in-depth examination of the ecological and evolutionary bases for behavioral diversity. Topics covered include behavior as an adaptive response, sexual selection, animal mating system, group living, and cooperative and competitive interactions. Current conceptual approaches to these topics are explored, with an emphasis upon rigorous testing of hypotheses drawn from the primary literature. Discussion sections are used to explore selected topics in greater detail and to stimulate critical review of recent research in behavioral ecology. Two midterms plus several discussion-based written assignments.

Instructor: Lacey

INTEGBI 146LF Behavioral Ecology with Laboratory 5 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 2 hours of lecture, 1 hour of discussion, and 3 hours of laboratory per week, plus 1 weekend field trip.

Prerequisites: 144 or C144 or consent of instructor.

An in-depth examination of the ecological and evolutionary bases for behavioral diversity. Topics covered include behavior as an adaptive response, sexual selection, animal mating systems, group living, and cooperative and competitive interactions. Current conceptual approaches to these topics are explored, with an emphasis upon rigorous testing of hypotheses drawn from primary literature. Hands-on laboratory training in the methods of experimental design, data collection, and data analysis.

Students will receive partial credit for 146LF after taking 146. Formerly known as 146L. Instructor: Lacey

INTEGBI 148 Comparative Animal Physiology 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall. Offered alternate years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1A-1B.

Comparative study of physiological systems among animal phyla. General physiological principles will be illustrated by examining variation in neural, muscular, endocrine, cardiovascular, respiratory, digestive, and osmoregulatory systems. Students will read original literature and give a group presentation in a symposium.

Students will receive no credit for 148 after taking 100A. Instructors: Full, Dudley, Koehl

INTEGBI C149/ESPM C149 Molecular Ecology 4 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: C163, 161, or Molecular and Cell Biology C142 (may be taken concurrently), or consent of instructor.

This course focuses on the use of molecular genetic information in ecology. Applications and techniques covered range from analysis of parentage and relatedness (DNA fingerprinting and multilocus genetic analysis) through gene flow, biogeographic history and community composition (comparative DNA sequencing) to analysis of diet and trophic interactions (biological isotopes). Grades are based on one final exam, problem sheets, and a critique of a recent research paper.

Students will receive no credit for C149 if they took 149 prior to spring 2003. Formerly known as 149.

INTEGBI 151 Plant Physiological Ecology 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. <BR/><BR/>Offered every other spring in odd-numbered years.

Grading: Letter grade.

Hours and format: 3 hours of lecture and 1 hour of discussion per week.

Prerequisites: Biology 1A,1B, or equivalent.

This course focuses on a survey of physiological approaches to understanding plant-environment interactions from the functional perspective. Lectures cover physiological adaptation; limiting factors; resources acquisition/allocation; photosynthesis, carbon, energy balance; water use and relations; nutrient relations; linking physiology; stable isotope applications in ecophysiology; stress physiology; life history and physiology; evolution of physiological performance; physiology population, community, and ecosystem levels.

Instructor: Dawson

INTEGBI 151L Plant Physiological Ecology Laboratory 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered every other spring in odd-numbered years.

Grading: Letter grade.

Hours and format: 3 hours of laboratory per week.

Prerequisites: Concurrent enrollment in 151.

The laboratory is focused on instructing you on observational and experimental approaches and methods used in plant physiological ecology. Students are introduced to a wide range of techniques and will make measurements on different plant species growing in the field or greenhouse (weeks 1-7). A group research project is required (weeks 9-12).

Instructor: Dawson

INTEGBI 152 Environmental Toxicology 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Background in biology or chemistry is recommended.

The environmental fate and effect of toxic substances from human activities, with emphasis on aquatic systems, including their biological effects from the molecular to the community level. Course will review pollutant types, principal sources, impacts on aquatic organisms, monitoring approaches, and regulatory issues.

Instructor: Weston

INTEGBI 153 Ecology 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1B or consent of instructor.

Principles of microbial, animal, and plant population ecology, illustrated with examples from marine, freshwater, and terrestrial habitats. Consideration of the roles of physical and biological processes in structuring natural communities. Observational, experimental, and theoretical approaches to population and community ecology will be discussed. Topics will include quantitative approaches relying on algebra, graph analysis, and elementary calculus. Discussion section will review recent literature in ecology.

Instructor: Ackerly

INTEGBI 153LF Laboratory in Population and Community Ecology 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 8 hours of laboratory per week, plus 2 or 3 weekend field trips.

Prerequisites: 153 (may be taken concurrently) or consent of instructor; introductory course in statistics strongly recommended.

Introduction to field and laboratory study of ecological patterns and processes in nature. Course begins with a series of group field exercises conducted in local terrestrial, aquatic, and marine habitats. These exercises emphasize sampling methodology, experimental design, and statistical interpretation of results. Latter half of course devoted to independent research projects. A written report and class presentation of project results are required.

Formerly known as 153L.

INTEGBI 154 Plant Ecology 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture/discussion per week.

Prerequisites: Biology 1B. Enrollment in accompanying lab course 154L is encouraged but not required.

An introduction to ecology of plants, covering individuals, populations, communities, and global processes. Topics include: form and function, population ecology, life histories, community structure and dynamics, disturbance and succession, diversity and global change.

Instructor: Ackerly

INTEGBI 154L Plant Ecology Laboratory 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 4 hours of laboratory per week and 2 or 3 1-day field trips.

Prerequisites: Biology 1B. Concurrent enrollment in 154.

Field and laboratory class in plant ecology. Laboratory exercises covering plant functional morphology, dispersal ecology, spatial dispersion in plant populations, environmental gradients and plant distributions, population dynamics simulations, and restoration ecology. Small-group independents projects, with write-ups and presentations. Concurrent enrollment in Integrative Biology 154 is required.

Instructor: Ackerly

INTEGBI C155/ANTHRO C129D Holocene Paleoecology: How Humans Changed the Earth 3 Units

Department: Integrative Biology; Anthropology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

Since the end of the Pleistocene and especially with the development of agriculturally based societies humans have had cumulative and often irreversible impacts on natural landscapes and biotic resources worldwide. Thus "global change" and the biodiversity crisis are not exclusively developments of the industrial and post-industrial world. This course uses a multi-disciplinary approach, drawing upon methods and data from archaeology, palynology, geomorphology, paleontology, and historical ecology to unravel the broad trends of human ecodynamics over the past 10,000 years.

Instructor: Kirch

INTEGBI C156/ESPM C103 Principles of Conservation Biology 4 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1.5 hours of Discussion per week for 15 weeks.

Prerequisites: Biology 1A-1B or equivalent.

A survey of the principles and practices of conservation biology. Factors that affect the creation, destruction, and distribution of biological diversity at the level of the gene, species, and ecosystem are examined. Tools and management options derived from ecology and evolutionary biology that can recover or prevent the loss of biological diversity are explored.

Instructor: Beissinger

INTEGBI 157LF Ecosystems of California 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 6 hours of Fieldwork per week for 15 weeks.

Prerequisites: Biology 1B or consent of instructor.

The ecosystems of California are studied from both an ecological and historical biogeographical perspective with a focus on terrestrial plant communities. Students learn how to identify about 150 species of native plants (mostly trees, but also other dominant plants from the non-forest biomes). Field trips occur each Friday and over several weekends. Students conduct group projects that involve plant inventories and data collection as well as how to collect plant specimens and use the Herbarium.

Formerly known as 157L. Instructor: Fine

INTEGBI 158LF/ESPM C107 Biology and Geomorphology of Tropical Islands 13 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 9 hours of lecture for 6 weeks; field projects for 6 weeks; 3 hours of lecture for 3 weeks.

Natural history and evolutionary biology of island terrestrial and freshwater organisms, and of marine organisms in the coral reef and lagoon systems will be studied, and the geomorphology of volcanic islands, coral reefs, and reef islands will be discussed. Features of island biogeography will be illustrated with topics linked to subsequent field studies on the island of Moorea (French Polynesia).

INTEGBI 159 The Living Planet: Impact of the Biosphere on the Earth System 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 2 hours of Discussion per week for 15 weeks.

Prerequisites: Biology 1B or consent of instructor.

Earth is a complex dynamic system. Interplay between its components (solid earth, oceans, and atmosphere) governs conditions on the planet's outside that we and other biota inhabit. In turn, life asserts a vast influence on the abiotic components; in fact, the biosphere itself is a crucial system component. We will explore the effect that 3.5 billion years of evolving biosphere had on System Earth and vice versa (e.g., in terms of climate), including the recent human impact on the system.

Students will receive two units of credit after taking Earth and Planetary Science 8, Earth and Planetary Science C141/Geography C141, or Geography 40. Instructors: Looy, Duijnstee

INTEGBI 160 Evolution 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1B.

An analysis of the patterns and processes of organic evolution. History and philosophy of evolutionary thought; the different lines of evidence and fields of inquiry that bear on the understanding of evolution. The major features and processes of evolution through geologic times; the generation of new forms and new lineages; extinction; population processes of selection, adaptation, and other forces; genetics, genomics, and the molecular basis of evolution; evolutionary developmental biology; sexual selection; behavorial evolution; applications of evolutionary biology to medical, agricultural, conservational, and anthropological research.

Instructors: Boore, Moritz, Padian

INTEGBI 161 Population and Evolutionary Genetics 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of lecture and 2 hours of computer and/or discussion per week.

Prerequisites: Biology 1A/1B, Mathematics 16A or 10A.

Population genetics provides the theoretical foundation for modern evolutionary thinking. It also provides a basis for understanding genetic variation within populations. We will study population genetic theory and use it to illuminate a number of different topics, including the existence of sex, altruism and cooperation, genome evolution speciation, and human genetic variation and evolution.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Nielson

INTEGBI 162 Ecological Genetics 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1B.

This course integrates ecology, genetics, and evolutionary biology. It presents contemporary approaches to studying evolution in natural populations, including analyzing heritability of ecologically important traits, using molecular techniques to decompose genotypes, documenting and measuring the magnitude of selection in natural systems, and using models to predict evolution in natural populations. Case studies are used to examine evolutionary effects of ecological interactions among organisms, the importance of population size and structure, and interactions among populations through migration and dispersal.

Instructor: Simms

INTEGBI 163 Molecular and Genomic Evolution 3 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

Prerequisites: Biology 1A-1B.

This course will introduce undergraduates to the study of evolution using molecular and genomic methods. Topics included will be rates of evolution, evolution of sex chromosomes, insertions and deletions of DNA sequences, evolution of regulatory genetic elements, methods of phylogenetic inference, gene duplication, multigene families, transposons, genome organization, gene transfer, and DNA polymorphism within species.

Instructors: Bachtrog, Slatkin

INTEGBI 164 Human Genetics and Genomics 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture and 2 hours of computer laboratory per week.

Prerequisites: Biology 1A, 1B, and Math 16A, or equivalent.

This course will introduce students to basic principles of genetics, including transmissions genetics, gene regulation, pedigree analysis, genetic mapping, population genetics, and the principles of molecular evolution. The course will also introduce students to recent developments in genomics as applied to problems in human genetic diseases, human history, and the relationship between humans and their closest relatives.

Instructors: Bachtrog, Nielsen, Slatkin

INTEGBI 166 Evolutionary Biogeography 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1B, 11, Geography 148 or Earth and Planetary Science 50.

The goals of the course are to (a) examine how geographically-linked characteristics of species influence their potential for evolution and extinction; and (b) provide an overview of the analytical techniques and applications for studying the interplay between geographic ranges, environment, evolution, and extinction. Accordingly, the course begins by examining what geographic ranges of species are and what controls them. We then will explore how geographic-range characteristics influence and interact with speciation and extinction processes. With that foundation, we will examine how species assemble into communities and how ecological processes govern distributions at the community and landscape levels, touching on such topics as community energetics, scaling issues, and the influences of humans on "natural" ecosystems. The last third of the course will be devoted to an overview of quantitative analytical techniques that commonly are used to study interactions between biogeogeographic ranges, evolutionary processes, extinction, and environmental change.

Instructor: Barnosky

INTEGBI 167 Evolution and Earth History: From Genes to Fossils 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Prerequisites: Biology 1A, 1B

The diversity of life is the product of evolutionary changes. This course will integrate fossil and molecular data to consider some of the outstanding questions in the study of evolution. Major topics covered include the origin and early evolution of life, the expansion of the biosphere through time, the generation of variation and the mechanisms of natural selection, genetics and developmental evolution, and the relationships between microevolution and macroevolution.


Instructors: Finnegan, Patel

INTEGBI 168 Systematics of Vascular Plants 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of Lecture per week for 15 weeks.

Prerequisites: Biology 1A-1B. Must be taken concurrently with 168L.

A discussion of the philosophy, principles, techniques, and history of botanical systemics. An outline of the major group of vascular plants and their evolution.

Instructor: Baldwin

INTEGBI 168L Systematics of Vascular Plants with Laboratory 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 6 hours of Laboratory per week for 15 weeks.

Prerequisites: Biology 1A-1B.

A discussion of the philosophy, principles, techniques, and history of botanical systemics. An outline of the major group of vascular plant and their evolution. Laboratory course devoted to a survey on a world-wide basis of the diversity of vascular plant families.

Students will receive partial credit for 168L after taking 168. Instructor: Baldwin

INTEGBI 169 Evolutionary Medicine 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Biology 1B, or equivalent.

This course explores the ways that evolutionary theory can illuminate our understanding of human health and disease. The integration of evolutionary concepts into health sciences can deepen our understanding of the origins of diseases and how human populations evolve in response to these ailments. The course begins with an introduction to evolutionary medicine (two hours of lecture) followed by an overview of human genetic variation and natural selection (six hours of lecture). With this foundation, we study the evolution of human diet and the evolution of human ecological relationships with the environment (six hours of lecture). We then explore the fascinating topic of infectious disease ecology from the perspective of both microbial and human evolutionary responses (nine hours of lecture). Next, we evaluate the fields of reproductive biology, gynecology, and infant/child health through an evolutionary lens (twelve hours of lecture). Finally, we examine evolutionary concepts in chronic metabolic and degenerative diseases associated with aging and lifestyle (ten hours of lecture).

Formerly known as 163. Instructor: Carlson

INTEGBI 173LF Mammalogy with Laboratory 5 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 2 hours of lecture and 6 hours of laboratory per week, plus 2 weekend field trips.

Prerequisites: 104LF.

An advanced course in the biology of mammals. Topics covered include elements of modern mammalian biology such as morphology, physiology, ecology, and behavior. For all topics, the traits that define mammals are emphasized, as is the variation on these themes evident within modern mammalian lineages. Laboratory and field explore the biology of modern mammals. Laboratories use the extensive collections of the Museum of Vertebrate Zoology to introduce students to mammalian diversity in a phylogenetic context.

Students will receive partial credit for 173LF after taking 173. Formerly known as 173L. Instructor: Lacey

INTEGBI 174LF Ornithology with Laboratory 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 2 hours of lecture and 6 hours of laboratory per week, plus 1 weekend field trip.

Prerequisites: 104L or consent of instructor.

An advanced course in the biology of birds. Laboratory: an introduction to the diversity, morphology, and general ecology of birds of the world.

Students will receive partial credit for 174LF after taking 174. Formerly known as 174L. Instructor: Bowie

INTEGBI 175LF Herpetology with Laboratory 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 2 hours of lecture and 4 hours of laboratory per week, plus 2 field trips.

Prerequisites: 104LF.

Lectures will introduce students to the diversity of amphibians and reptiles on a world-wide basis, with an emphasis on systematics, ecology, morphology, and life history. Laboratories will teach students the diagnostic characteristics and some functional attributes of amphibians and reptiles on a world-wide basis. Field trips will acquaint students with techniques for collecting, preserving, identifying, and studying amphibians and reptiles.

Students will receive partial credit for 175LF after taking 175. Formerly known as 175L. Instructor: McGuire

INTEGBI C176L/ESPM C115C Fish Ecology 3 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of lecture and 3 hours of laboratory per week; 1 Saturday field trip.

Prerequisites: Introductory course in biological science; upper division or graduate standing.

Introduction to fish ecology, with particular emphasis on the identification and ecology of California's inland fishes. This course will expose students to the diversity of fishes found in California, emphasizing the physical (e.g., temperature, flow), biotic (e.g., predation, competition), and human-related (e.g., dams, fisheries) factors that affect the distribution, diversity, and abundance of these fishes.

Instructor: Carlson

INTEGBI N176L Laboratory in Ichthyology 2 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Summer

Grading: Letter grade.

Hours and format: 6 hours of laboratory per week for 8 weeks plus 2 field trips.6 hours of laboratory per week, plus 3 field trips.

Prerequisites: 176 (may be taken concurrently) and Biology 1A-1B. The laboratory is complimentary to 176 and is highly recommended, though not mandatory.

Laboratory on the biology of fishes. Students will experience hands-on working with fish, including identification, experimental methods, illustration. Particular emphasis will be on California fishes.

INTEGBI 181L Paleobotany - The 500-Million Year History of a Greening Planet 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of lecture and 3 hours of laboratory per week.

Prerequisites: Courses in botany and geology are recommended.

Introduction to the evolution of plants and terrestrial
ecosystems through time. From the invasion of land to the present, we will follow the
evolution of major plant groups through important moments of the Phanerozoic eon (the past
540 million years). By studying fossilized plant assemblages, we will interpret how major
environmental changes unfolded across landscapes in the past and how plants have influenced
the shaping of our planet. Lectures will be complemented by an interactive laboratory covering
paleobotanical research techniques, study of fossil and living plant form and function in the lab
and field, and analysis of peer-reviewed literature.

Formerly known as Integrative Biology 181. Instructor: Looy

INTEGBI 183L Evolution of the Vertebrates with Laboratory 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall. Offered alternate years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 2 hours of Laboratory per week for 15 weeks.

Prerequisites: Biology 1B; introductory courses in earth history and zoology are recommended.

Introduction to vertebrate paleontology, focusing on the history and phylogeny of vertebrates ranging from fishes to humans. Emphasis: evolution, taxonomy, functional morphology, faunas through time, problems in vertebrate history, including diversity through time and extinction. Laboratory: vertebrate fossils, focusing on demonstration and study of problems related to taxonomy, evolution, functional morphology, structures, preservation of fossil vertebrates, and their faunas through time.

Students will receive partial credit for 183L after taking 183. Instructor: Padian

INTEGBI 184L Morphology of the Vertebrate Skeleton with Laboratory 4 Units

Department: Integrative Biology

Course level: Undergraduate

Term course may be offered: Fall. Offered odd-numbered years.

Grading: Letter grade.

Hours and format: 2 hours of lecture and 6 hours of laboratory and 1 hour of discussion per week.

Prerequisites: Anthropology 1 and Biology 1B.

Lectures on comparative osteology of vertebrates, with emphasis on selected groups of terrestrial vertebrates considered in paleoecological, paleoclimatological, and biostratigraphic analyses. Laboratory: comparative osteology of vertebrates, with emphasis on selected groups of vertebrates. Structure, anatomy, morphology, function, and development of the vertebrate skeleton.

Students will receive partial credit for 184L after taking 184. Instructor: Barnosky

INTEGBI C185L/ANTHRO C100 Human Paleontology 5 Units

Department: Integrative Biology; Anthropology

Course level: Undergraduate

Term course may be offered: Spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

Prerequisites: Anthropology 1, Biology 1A-1B.

Origin and relationships of the extinct forms of mankind.

Instructor: White

INTEGBI C187/ANTHRO C124C Human Biogeography of the Pacific 3 Units

Department: Integrative Biology; Anthropology

Course level: Undergraduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

Prerequisites: Biology 1B strongly recommended, or evidence the student has mastered an equivalent set of basic concepts in evolution and ecology.

This course examines the history of human dispersal across Oceania from the perspectives of biogeography and evolutionary ecology. H. sapiens faced problems of dispersal, colonization, and extinction, and adapted in a variety of ways to the diversity of insular ecosystems. A dual evolutionary model takes into account cultural evolution and transmission, as well as biological evolution of human populations. This course also explores the impacts of human populations on isolated and fragile insular ecosystems, and the reciprocal effects of anthropogenic change on human cultures.

Instructor: Kirch

INTEGBI 190 Seminar for Integrative Biology Majors 1 - 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Letter grade.

Hours and format: 1 to 3 hour of Seminar per week for 15 weeks. 1.5 to 5.5 hours of Seminar per week for 8 weeks. 2.5 to 7.5 hours of Seminar per week for 6 weeks.

Prerequisites: Consent of instructor.

This upper-division undergraduate course will allow students to pursue specialized topics in biology in a seminar format. The specific content of the course will vary based on the topic and the instructor. In general, weekly meetings will provide a forum for extended discussion of selected aspects of evolutionary biology. Supplementary readings and assignments will provide critical background information and keep students engaged in relevant topics between weekly meetings.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 191 Directed Undergraduate Research 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Letter grade.

Hours and format: 9 hours of supervised independent research per week. 13 and 1 half hours of supervised independent research per week for 10 weeks.

Prerequisites: Consent of instructor and departmental adviser.

This course is intended for advanced undergraduates wishing to pursue independent research projects under the mentorship of an IB faculty member. Research projects will be rigorous and will provide significant training in the methods of evoluntionary research. A project proposal is required to enroll and students are expected to porduce a substantial written summary of their work.

INTEGBI 194 Undergraduate Student Instructor for Integrative Biology Courses 1 - 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: 6 hours of lecture per week per unit for 8 weeks. 3 to 4 hours of lecture per week per unit.

Prerequisites: Must have completed course applying to UGSI with a grade of B or better; or consent of instructor

UGSI will work under supervision of instructor and/or GSI. The UGSI will attend any mandatory preparatory and review meetings, be available in the classroom (discussion or laboratory) to respond to student questions, facilitate lesson plans, perform other tasks as assigned. UGSIs do not evaluate students' work or assign grades.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI C195/PB HLTH C117 Introduction to Global Health Disparities Research 2 Units

Department: Integrative Biology; Public Health

Course level: Undergraduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 1 hour of Lecture and 1 hour of Discussion per week for 15 weeks.

This course is designed to prepare trainees in the UC Berkeley "Minority Health/Global Health" (MH/GH) program to conduct a ten-week infectious disease research project in a disease-endemic country. The course provides a background in neglected tropical disease research, international research ethics, and the conduct of health research in low-resource settings.

Instructor: Reingold

INTEGBI H196A Thesis Course 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Letter grade.

Hours and format: Individually arranged.

Prerequisites: Open only to students in Honors Program.

Individual study and research for at least one academic year on a special problem to be chosen in consultation with a member of the staff; preparation of the thesis on broader aspects of this work.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI H196B Thesis Course 3 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Letter grade.

Hours and format: Individually arranged.

Prerequisites: Open only to students in Honors Program.

Individual study and research for at least one academic year on a special problem to be chosen in consultation with a member of the staff; preparation of the thesis on broader aspects of this work.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 197 Supervised Internship 1 - 4 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: Hours by arrangement with faculty. Hours by arrangement with faculty.

Prerequisites: Consent of Integrative Biology faculty sponsor.

Supervised experience relevant to specific topics of biology in off-campus organizations. Written report and evaluation from internship supervisor required.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 198 Supervised Group Study and Research By Upper Division Students 1 - 4 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: 1 to 4 hour of Directed group study per week for 15 weeks. 2 to 7.5 hours of Directed group study per week for 8 weeks. 2.5 to 10 hours of Directed group study per week for 6 weeks.

Undergraduate research by small groups.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Enrollment is restricted; see the Introduction to Courses and Curricula section of this catalog.

INTEGBI 199 Supervised Independent Study and Research 1 - 4 Units

Department: Integrative Biology

Course level: Undergraduate

Terms course may be offered: Fall, spring and summer

Grading: Offered for pass/not pass grade only.

Hours and format: Hours to be arranged.

Prerequisites: Background courses in chosen subjects.

Enrollment restrictions apply; see department.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Enrollment is restricted; see the Introduction to Courses and Curricula section of this catalog.

INTEGBI 200A Principles of Phylogenetics: Systematics 4 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring. Offered even-numbered years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

The core theory and methodology for phylogenetic systematics with emphasis on both morphology and molecules, and both living and fossil organisms. Topics include homology, character analysis, competing optimality criteria, classification, and a brief introduction to comparative methods. Laboratories are closely integrated with lectures and cover the major algorithms and software. Requirements include a practical term project. Note: this course and 200B may be taken in either order or alone.

Instructors: Mishler, Lindberg, Will

INTEGBI 200B Principles of Phylogenetics: Ecology and Evolution 4 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring. Offered odd-numbered years.

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

The uses of phylogenetic trees in comparative biology. Covers the many applications of phylogenetics to biogeography, speciation, conservation, population genetics, ecology, behavior, development, functional morphology, and macroevolution that are revolutionizing those fields. Laboratories are closely integrated with lectures and cover algorithms and software. Requirements include a practical term project. Note: this course and 200A may be taken in either order or alone.

Instructors: Mishler, Ackerly, Lindberg

INTEGBI C204/ESPM C204 Research Reviews in Animal Behavior: Behavior Review 1 Unit

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 1 hours of seminar per week.

Prerequisites: Graduate standing, basic course in animal behavior. Instructor approval required.

This course will provide a rigorous, critical review of current research in animal behavior. Emphases will include hypothesis testing and experimental design, as well as methods of data collection and analysis. Each week, a student in the course will present original research in the form of a seminar presentation, grant proposal, or manuscript. Through discussion with seminar participants, presenters will gain critical feedback regarding their research.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructors: Lacey, Caldwell, Bentley, Elias

INTEGBI C205/ENE,RES C205/ESPM C205 Quantitative Methods for Ecological and Environmental Modeling 3 Units

Department: Integrative Biology; Energy and Resources Group; Environ Sci, Policy, and Management

Course level: Graduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

Prerequisites: Consent of instructor.

This course will review the background mathematical and statistical tools necessary for students interested in pursuing ecological and environmental modeling. Topics include linear algebra; difference equation, ordinary differential equation, and partial differential equation models; stochastic processes; parameter estimation; and a number of statistical techniques. This course will be recommended as a prerequisite for advanced modeling courses in Integrative Biology, Energy and Resources Group, and Environmental Science, Policy, and Management.

INTEGBI 206 Statistical Phylogenetics 3 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

Prerequisites: College level course in calculus.

This course is aimed at students who wish to understand the evolutionary models and methods for estimating phylogenies (which are trees representing how organisms are related to one another). Topics include continuous-time Markov chains as applied in phylogenetics; maximum likelihood estimation; Bayesian estimation; the combinatorics of evolutionary trees; Markov chain Monte Carlo; distance and parsimony methods for estimating trees; optimization strategies for finding best trees. Students will learn to write computer programs that implement many of the methods discussed in class, and apply their knowledge in a research project.

Instructor: Huelsenbeck

INTEGBI C215/EPS C301/GEOG C301 Communicating Ocean Science 4 Units

Department: Integrative Biology; Earth and Planetary Science; Geography

Course level: Professional course for teachers or prospective teachers

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2.5 hours of Lecture, 1 hour of Discussion, and 2 hours of Fieldwork per week for 15 weeks.

Prerequisites: One course in introductory biology, geology, chemistry, physics, or marine science required and interest in ocean science.

For graduate students interested in improving their ability to communicate their scientific knowledge by teaching ocean science in elementary schools or science centers/aquariums. The course will combine instruction in inquiry-based teaching methods and learning pedagogy with six weeks of supervised teaching experience in a local school classroom or the Lawrence Hall of Science with a partner. Thus, students will practice communicating scientific knowledge and receive mentoring on how to improve their presentations.

Instructor: Ingram

INTEGBI C216/ESPM C216 Freshwater Ecology 3 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of Lecture and 1 hour of Discussion per week for 15 weeks.

This graduate course will combine formal lectures and discussion, with the overall goal of exposing students to general concepts in freshwater ecology. We will discuss a broad range of topics including freshwater environments and biota, natural selection and adaptive evolution, food webs and trophic cascades, cross-ecosystem linkages, and social-ecological resilience of freshwater ecosystems under global change. Upper division undergraduates are welcome, with permission of the instructors.

Instructors: Carlson, Power

INTEGBI C217/BIO ENG C217/MEC ENG C217 Biomimetic Engineering -- Engineering from Biology 3 Units

Department: Integrative Biology; Bioengineering; Mechanical Engineering

Course level: Graduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

Prerequisites: Graduate standing in engineering or consent of instructor.

Study of nature's solutions to specific problems with the aim of determining appropriate engineering analogs. Morphology, scaling, and design in organisms applied to engineering structures. Mechanical principles in nature and their application to engineering devices. Mechanical behavior of biological materials as governed by underlying microstructure, with the potential for synthesis into engineered materials. Trade-offs between redundancy and efficiency. Students will work in teams on projects where they will take examples of designs, concepts, and models from biology and determine their potential in specific engineering applications.

Instructor: Dharan

INTEGBI 222 Seminar in Locomotion Energetics and Biomechanics 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Prerequisites: Consent of instructor.

Discussion and critique of scientific literature and current topics in the biomechanics and energetic cost of locomotion. Emphasis on terrestrial-legged locomotion. Topics include efficiency, musculoskeletal design, energy-saving mechanisms, muscle mechanics, gaits, effects of scaling, and comparative aspects.

INTEGBI 223 Seminar in Physiological Bases of Physical Activity 2 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Fall

Grading: Letter grade.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Prerequisites: 123A, 123AL.

Immediate and long-range adaptations of the body to exercise. Physiological limits and work capacities in relation to age, sex, diet, environmental factors, and nature of activity.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Formerly known as Human Biodynamics 205. Instructor: Brooks

INTEGBI C226/ESPM C225 Isotopics 2 Units

Department: Integrative Biology; Environ Sci, Policy, and Management

Course level: Graduate

Term course may be offered: Fall

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 3 hours of Seminar per week for 10 weeks.

This seminar will explore current topics that employ the use of stable isotopes. Discussion topics include the areas of biology, paleontology, biogeochemistry, soil science, and atmospheric science. Students will be required to lead at least one discussion of relevant literature in the topic area.

Instructors: Amundson, Dawson, Mambelli

INTEGBI C227/EPS C241/ESPM C220 Stable Isotope Ecology 5 Units

Department: Integrative Biology; Earth and Planetary Science; Environ Sci, Policy, and Management

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.

Prerequisites: Graduate standing.

Course focuses on principles and applications of stable isotope chemistry as applied to the broad science of ecology. Lecture topics include principles of isotope behavior and chemistry, and isotope measurements in the context of terrestrial, aquatic, and marine ecological processes and problems. Students participate in a set of laboratory exercises involving preparation of samples of choice for isotopic analyses, the use of the mass spectrometer and optical analysis systems, and the anlaysis of data.

Instructors: Amundson, Dawson, Mambelli

INTEGBI C229/EPS C229 Introduction to Climate Modeling 3 Units

Department: Integrative Biology; Earth and Planetary Science

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Lecture per week for 15 weeks.

This course emphasizes the fundamentals of the climate system via a hierarchy of climate models. Topics will include energy balance, numerical techniques, climate observations, atmospheric and oceanic circulation and heat transports, and parameterizations of eddy processes. The model hierarchy will also explore nonlinear and stochastic processes, and biogeochemistry. Students will build computational models to investigate climate feedbacks, climate sensitivity, and response times.

Course may be repeated for credit with consent of instructor. Course may be repeated for credit when topic changes. Instructors: Fung, Powell

INTEGBI 230 Marine Science Review 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1 hour of Seminar per week for 15 weeks.

Prerequisites: Senior or graduate standing; consent of instructor.

Reports and discussion of original research in marine science.

Instructors: Herrlinger, Stillman

INTEGBI 232 Seminar in Biomechanics 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Prerequisites: Consent of instructor.

Presentation, discussion, and critique of current literature in scientific research and current topics in comparative biomechanics which include solid and fluid mechanics, locomotion, and energetics.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 234 Seminar on Biology of Amphibians and Reptiles 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of Seminar per week for 8 weeks.

Prerequisites: Graduate standing and consent of instructor.

Review of current research activity and literature concerning the biology of amphibians and reptiles.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 241 Advanced Topics in Endocrine-Regulated Development 3 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 3 hours of Seminar per week for 15 weeks.

This course will examine intentional endocrine disruption, such as the use of pharmaceuticals to regulate hormones in humans, livestock, and wildlife. We will also evaluate endocrine disrupting pollutants and their impacts on wildlife and humans, including their potential role in cancer.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Hayes

INTEGBI 245 Functional Neuroanatomy 2 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 2 hours of Lecture per week for 15 weeks.

Prerequisites: Consent of instructor.

Development, structural (gross and microscopic) and functional relationships of the mammalian central nervous system.

Instructor: Diamond

INTEGBI 245L Functional Neuroanatomy Laboratory 2 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 6 hours of Laboratory per week for 15 weeks.

Prerequisites: Consent of instructor.

Histological examination of the human nervous system; gross dissection of the human brain.

Instructor: Diamond

INTEGBI 246 Seminars in Systems Biology 2 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 1 hour of lecture and 1 hour of discussion/modeling per week.

Prerequisites: Consent of instructor.

This course discusses seminal papers in the field of systems biology with particular emphasis on gene regulation and cell biology. The course covers the critical analysis of primary research data, computational modeling, and important theoretical concepts in systems biology. Topics vary from year to year.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Lim

INTEGBI 248 Comparative Physiology and Endocrinology Seminar 1 Unit

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1 hour of Seminar per week for 15 weeks.

Prerequisites: Consent of instructor.

Reviews and reports of current research in vertebrate endocrinology and physiology.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Firestone

INTEGBI 249 Seminar on Evolutionary Genetics 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1 hour of Discussion per week for 15 weeks.

Prerequisites: Consent of instructor.

Recent developments in evolutionary genetics will be discussed in a seminar format.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 250 Seminar in Ecology 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Prerequisites: 153.

Readings and discussion of current topics.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 251 Ecological Research Reviews 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1.5 hours of Seminar per week for 15 weeks.

Prerequisites: Graduate standing and consent of instructor.

Reports and discussions of original research.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Formerly known as 254.

INTEGBI 257 Current Topics in Behavioral Physiology 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Prerequisites: C144 or consent of instructor.

Topics to vary. Report and discussion of current literature.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 259 Advanced Paleoecology 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Prerequisites: Consent of instructor.

Topics vary from year to year but will include paleoecology of major groups of organisms or major environments from population, community evolutionary, or taxonomic persepectives.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 262 Seminar in Computational Biology 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1 hour of Lecture and 1 hour of Discussion per week for 15 weeks.

Prerequisites: Consent of instructor.

Students will discuss original papers in the general area of computational biology and will discuss new research presented by instructors in the course and by invited speakers from other departments at UC Berkeley and from other universities and research groups.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructors: Huelsenbeck, Nielsen, Slatkin

INTEGBI 263 Genetics and the Evolution of the Skeleton 2 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Letter grade.

Hours and format: 1 hour of Seminar per week for 15 weeks.

Prerequisites: A graduate-level course in biology or consent of instructor.

In this seminar, we will explore the genetic underpinnings of vertebrate skeletal variation and review how such information is being incorporated into evolutionary and paleontological studies. Topics include quantitative genetic analyses of cranial variation and developmental genetics of the limb and dentition. This course will be tailored each semester to cover new research; therefore, students may enroll in this course multiple semesters.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Hlusko

INTEGBI 264 Seminar in Evolutionary Biology of the Vertebrates 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1 hour of Seminar per week for 15 weeks.

Prerequisites: Graduate standing; consent of instructor.

Formerly Presentation of results of original research by students, faculty, and visitors.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 268 Seminar in Evolution above the Species Level 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring. Offered alternate years.

Grading: Letter grade.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Current issues in macroevolution and paleobiology, using both neontological and paleontological data.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 281 Seminar in Evolution 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Advanced study and current literature in various fields of evolution. Topics vary from year to year.

Instructor: Padian

INTEGBI 283 Seminar in Vertebrate Evolution and Paleontology 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 1 hour of Seminar per week for 15 weeks.

Prerequisites: 183, 183L or consent of instructor.

Presentations and discussions of original research and new literature in vertebrate evolution and paleontology. Syllabus and reading list will vary as topics change from semester to semester. Open to Undergraduate students with permission. Enrollment limit: 20.

Enrollment is restricted; see the Introduction to Courses and Curricula section of this catalog. Instructor: Padian

INTEGBI 286 Seminars in Paleontology 2 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of Seminar per week for 15 weeks.

Advanced study and current literature in various fields of paleontology. Topics vary from year to year.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 290 Research Seminar 1 Unit

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 1 hour of Seminar per week for 15 weeks.

Prerequisites: Consent of instructor.

Advanced study in various fields of Integrative Biology. Topics will be announced in advance of each semester. Enrollment in more than one section permitted.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 291 Research Seminar 1 Unit

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of Seminar per week for 7.5 weeks.

Review and discussion of topics of current interest. Topics to vary.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 292 Integrative Biology Colloquium 0.0 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 1 hour of meeting per week.

Meetings for the presentation of original work by faculty, visiting lecturers, and graduate students.

INTEGBI 296 Special Study for Graduate Students 1 - 4 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall, spring and summer

Grading: Letter grade.

Hours and format: Individual conferences.

Reading or other advanced study by arrangement with a staff member.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Formerly known as Zoology 296.

INTEGBI 297 Directed Field Studies 1 - 8 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: Field work.

Open to qualified students directly engaged in field studies.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 298 Special Study in Integrative Biology 1 - 12 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: Hours to be arranged.

Prerequisites: Consent of instructor.

Graduate research by small groups.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 299 Graduate Research 1 - 12 Units

Department: Integrative Biology

Course level: Graduate

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: Individual study.

Credit awarded according to work planned and accomplished.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI N299 Graduate Research 1 - 6 Units

Department: Integrative Biology

Course level: Graduate

Term course may be offered: Summer

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: Individual study.

Prerequisites: Graduate standing.

Graduate student research.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 304 Dissemination of Research: Your Interface with the Public 2 Units

Department: Integrative Biology

Course level: Professional course for teachers or prospective teachers

Terms course may be offered: Fall and spring

Grading: Letter grade.

Hours and format: 2 hours of lecture/discussion per week.

This course will consist of lectures and class discussions about mechanisms of communicating about science to the public. We will consider how to convey the issues, process, and findings of scientific research to a variety of audiences using different media (e.g., posters, web pages, newsletters, newspaper and magazine articles, books, television). Projects conducted by teams of students under the direct supervision of the instructors will include preparation of outreach materials (e.g., posters, newsletters, web pages).

INTEGBI 305 Academic Survivorship 2 Units

Department: Integrative Biology

Course level: Professional course for teachers or prospective teachers

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of seminar per week and assignments.

Series of lectures and workshops to prepare graduate students for many aspects of academic careers, including grant proposal writing, giving talks at meetings or to academic departments, preparing job applications and having job interviews, advising graduate students and postdocs, reviewing manuscripts and grant proposals, service activities and time management, working at teaching college vs. research universities, alternative careers, etc.

INTEGBI 375 Teaching Colloquium: Graduate Student Instructor Training 2 Units

Department: Integrative Biology

Course level: Professional course for teachers or prospective teachers

Term course may be offered: Fall

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 2 hours of seminar plus workshops per week.

Series of workshops and seminars involving graduate students and faculty participation. The main objectives of this course are to train graduate students to become effective instructors and to discuss important issues that graduate students face when teaching undergraduate classes.

Formerly known as Integrative Biology 303.

INTEGBI 400 Training in Stable Isotope Methods and Mass Spectrometry 1 Unit

Department: Integrative Biology

Course level: Other professional

Term course may be offered: Fall

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: 3 hours of lecture and laboratory training per week.

Prerequisites: Consent of instructor.

An intensive lecture and laboratory training course on the fundamental principles and practical applications of stable isotope methods in biogeochemistry, ecology, physiology, and environmental science. Topics covered are sample preparation, operating of an isotope ratio mass spectrometer, and analysis of stable isotope data. This course is required for all students interested in using the facilities housed in the Center for Stable Isotope Biogeochemistry for their research.

Instructor: Dawson

INTEGBI C407/PHYS ED C407 Introduction to Scientific Diving 3 Units

Department: Integrative Biology; Physical Education

Course level: Other professional

Terms course may be offered: Spring and summer

Grading: Letter grade.

Hours and format: 2 hours of lecture and 6 hours of laboratory per day for 12 days.

Prerequisites: Advanced scuba certification, swim test, medical exam, and consent of instructor.

Diving physics, physiology, medicine, rescue, decompression, theory, navigation, environment, marine life, research methods, equipment, and University regulations. Course leads to University certification to use underwater life support apparatus for study or research under University auspices.

INTEGBI 601 Individual Study for Master's Students 1 - 8 Units

Department: Integrative Biology

Course level: Graduate examination preparation

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: Individual conferences.

Individual study for the comprehensive requirements in consultation with the major adviser. Units may not be used to meet either unit or residence requirements for a master's degree.

Course may be repeated for credit. Course may be repeated for credit when topic changes.

INTEGBI 602 Individual Study for Doctoral Students 1 - 8 Units

Department: Integrative Biology

Course level: Graduate examination preparation

Terms course may be offered: Fall and spring

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: Individual conferences.

Individual study in consultation with the major adviser. Intended to provide an opportunity for qualified students to prepare themselves for the various examinations required for candidates for the Ph.D.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Course does not satisfy unit or residence requirements for doctoral degree.

INTEGBI N602 Individual Study for Doctoral Students 1 - 6 Units

Department: Integrative Biology

Course level: Graduate examination preparation

Term course may be offered: Summer

Grading: Offered for satisfactory/unsatisfactory grade only.

Hours and format: Individual conferences.

Formerly < Paleon 602, Zoology 602, Botany 602, Physiol 602, Anatomy 602> Individual study in consultation with the major field adadviser. Intended to provide an opportunity for qualified students to prepare themselves for the various examinations required for candidates for the Ph.D.

Course may be repeated for credit. Course may be repeated for credit when topic changes. Course does not satisfy unit or residence requirements for doctoral degree.

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