Bioengineering
College of Engineering
Department Office: 306 Stanley Hall, (510) 642-5833
Chair: Kevin Healy, PhD
Department Website: Bioengineering
Overview
Bioengineering applies engineering principles and practices to living things, to solve some of the most challenging problems that face our world today. In Bioengineering, also known as Biomedical Engineering, our work is concentrated on high-impact applications instrumentation, molecular and cellular engineering, and computational biosciences that will bring about major advances in medicine and the life sciences.
Founded in 1998, the department is supported by exceptional faculty, strong ties to other departments on campus, and close collaborations with other institutions such as UC San Francisco and Lawrence Berkeley National Laboratory. We continue to expand our department with new faculty, staff, facilities, and research programs.
See the College of Engineering Undergraduate Guide for more information.
Undergraduate Program
Rated one of the top 10 bioengineering undergraduate programs in the country, Bioengineering at Berkeley is a multidisciplinary major intended for academically strong students who excel in the physical sciences, mathematics, and biology. Coursework provides a strong foundation in engineering and the biological sciences, with the freedom to explore a variety of topics and specialize in advanced areas of research. All students benefit from intensive group design work, either through a senior capstone project or through independent research in faculty laboratories.
The stimulating environment of Berkeley offers a wealth of opportunity for learning, research, service, and community involvement, and provides dedicated students the knowledge and skills to become the next leaders in bioengineering.
Our major features small, specialized upper division courses and direct interaction with faculty. We offer six distinct concentrations: Biomaterials, Biomechanics and Cell & Tissue Engineering; Biomedical Devices; Computational Bioengineering; Imaging; Premed; and Synthetic Biology.
Major Requirements
Students must complete a minimum of 120 units, in which they must satisfy the University of California and Berkeley campus requirements outlined in this Bulletin. In addition, students must complete the requirements for the College of Engineering and the bioengineering program. Full details on these requirements can be found in the College of Engineering Undergraduate Guide .
Undergraduate Program in Bioengineering*
| Course | Fall | Spring |
|---|---|---|
| Freshman Year | ||
| Chemistry 1A and 1AL – General Chemistry or Chemistry 4A – General Chemistry and Quantitative Analysis (1 ) | 4 | - |
| Chemistry 3A and 3AL – Chemical Structure and Reactivity or Chemistry 112A – Organic Chemistry (1 ) | - | 5 |
| BioE 10 – Introduction to Biomedicine for Engineers (12 ) | 4 | - |
| E 7 – Introduction to Computer Programming for Scientists & Engineers or CS 61A – Structure and Interpretation of Computer Programs | - | 4 |
| Mathematics 1A – Calculus | 4 | - |
| Mathematics 1B – Calculus | - | 4 |
| Physics 7A – Physics for Scientists and Engineers | - | 4 |
| Seminar: BioE 24 – Aspects of Bioengineering and BioE 25 – Careers in Biotechnology (2 ) | 1 | 1 |
| Reading and Composition Course from List A (3 ) | 4 | - |
| Total | 17 | 18 |
| Sophomore Year | ||
| Biology 1A and 1AL – General Biology | - | 5 |
| Engineering/Biology Preparation (4 ) | 3 | 3 |
| Mathematics 53 – Multivariable Calculus | 4 | - |
| Mathematics 54 - Linear Algebra and Differential Equations | - | 4 |
| Physics 7B – Physics for Scientists and Engineers | 4 | - |
| Reading and Composition Course from List B (3 ) | 4 | - |
| Total | 15 | 12 |
| Junior Year | ||
| Bioengineering Fundamentals (see concentrations for recommendations) (5 ) | 4 | 4 |
| Engineering Topic (see concentrations for recommendations) (6 ) | 3 | - |
| Technical Electives (see concentrations for recommendations) (7 ) | 4 | 3 |
| Upper division biology elective (see concentrations for recommendations) (8 ) | - | 3 |
| First Additional Humanities/Social Science Course (2 ,3 ) | 3-4 | - |
| BioE 100 – Ethics in Science and Engineering or Second Additional Humanities/Social Science Course (with Ethics Content) (2 ,3 ) | - | 3-4 |
| Total | 14-15 | 13-14 |
| Senior Year | ||
| Bioengineering Lab Course (11 ) | 4 | - |
| Bioengineering Topics (see concentrations for recommendations) (9 ) | 4 | 4 |
| Engineering Topic (see concentrations for recommendations) (6 ) | - | 4 |
| Technical Elective (see concentrations for recommendations) (7 ) | 3 | - |
| Bioengineering Design Project or Research (10 ) | - | 4 |
| Third and Fourth Additional Humanities/Social Science Courses (2 ,3 ) | 3-4 | 3-4 |
| Total | 14-15 | 15-16 |
|
Notes 1 Chemistry 4A and 112A/B are intended for students majoring in chemistry or a closely related field. Note: Prerequisites to Chemistry 112A/B include Chemistry 1A and Chemistry 1B (or Chemistry 4A and Chemistry 4B). 2 This requirement may be completed at any time in the program. 3 The Humanities/Social Science (H/SS) requirement includes two approved reading and composition courses and four additional approved courses, with which a number of specific conditions must be satisfied. Reading and Composition “A” and “B” must be completed by no later than the end of the sophomore year. The remaining courses may be taken at any time during the program. See the website for complete details and a list of approved courses. Consult the “Ethics Content List” on the previous page for courses with ethics content. 4 Select two from the Engineering/Biology Preparation list . 5 Choose courses from the approved Bioengineering Fundamentals list . 6 Choose courses from the approved Engineering Topics list . 7 Choose courses from the approved Technical Elective list . Pre-Med students should take Chemistry 3B/3BL and Biology 1B. 8 Choose courses from the approved Upper Division Biology list . 9 Choose courses from the Bioengineering Topics list . 10Choose course from Bioengineering Design Project or Research list . 11 Choose course from Bioengineering Lab list
. 12 Junior Transfer admits are exempt from completing BIOE 10 * A minimum of 120 units is required for graduation. |
||
Joint Major in Bioengineering/Materials Science and Engineering
The Department of Bioengineering offers a joint major with The Department of Materials Science and Engineering for students who have an interest in the field of biomaterials. The broad curriculum includes exposure to fundamental courses in engineering and life sciences and will allow students to understand the interface between the two major fields. Students taking this joint major will successfully compete for jobs in the field of biomaterials in academia, industry, and government.
Bioengineering Minor
The department offers a minor in bioengineering that is open to all students who are not majoring in bioengineering and who have completed the necessary prerequisites for the minor requirements. Information is available in 306 Stanley Hall.
Graduate Program
The Department of Bioengineering offers two professional Master's degrees and a joint PhD program.
The Master of Engineering (MEng) is a one-year masters degree with a strong emphasis on engineering and entrepreneurship designed for students planning to move directly into industry after completing the program.
The Master of Translational Medicine (MTM) program links the Department of Bioengineering at Berkeley with the Department of Bioengineering and Therapeutic Sciences at UCSF, and is designed to train students in applying translational research and engineering approaches to solve fundamental problems in healthcare delivery. This one-year program should appeal to engineers, scientists and clinicians who seek to bring innovative treatments and devices into clinical use.
The PhD in Bioengineering is granted jointly by Berkeley and UCSF, two of the top public universities in the world in health sciences and engineering. Our interdisciplinary program combines the outstanding resources in biomedical and clinical sciences at UCSF with the excellence in engineering, physical, and life sciences at Berkeley.
All students have full access to the breadth of resources and courses on both campuses, and the opportunity to work with over 100 affiliated faculty in the colleges of engineering, chemistry and biological sciences at Berkeley and medical and dental schools at UCSF. Our program offers students unparalleled opportunities for fundamental and applied bioengineering research in a wide variety of related fields. Innovation and collaboration across campuses and disciplines is encouraged, and often led by graduate students.
Students with a BA or BS degree in engineering, biology, or other science are eligible for admission. Students can obtain additional information and application materials by contacting the Bioengineering Graduate Program, 306 Stanley Hall, University of California, Berkeley; Berkeley, CA 94720-1762. Phone: (510) 642-9931. Website: bioegrad.berkeley.edu .
BIO ENG 10 Introduction to Biomedicine for Engineers 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
This course is intended for lower division students interested in acquiring a foundation in biomedicine with topics ranging from evolutionary biology to human physiology. The emphasis is on the integration of engineering applications to biology and health. The goal is for undergraduate engineering students to gain sufficient biology and human physiology fundamentals so that they are better prepared to study specialized topics, e.g., biomechanics, imaging, computational biology, tissue engineering, biomonitoring, drug development, robotics, and other topics covered by upper division and graduate courses in UC Berkeley departments of Molecular and Cell Biology, Integrative Biology, Bioengineering, Electrical Engineering and Computer Science, Mechanical Engineering, and courses in the UC San Francisco Division of Bioengineering. The specific lecture topics and exercises will include the key aspects of genomics and proteomics as well as topics on plant and animal evolution, stem cell biomedicine, and tissue regeneration and replacement. Medical physiology topics include relevant engineering aspects of human brain, heart, musculoskeletal, and other systems.
Instructors: Conboy, Kumar
BIO ENG 22 Biotechnology 3 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: 22L (must be taken concurrently).
This course is intended to introduce students to a variety of fields that fall under the biotechnology umbrella. In general, these fields include medical, microbial, agricultural, animal, and forensic biotechnology. Students in this course will learn the types of biotechnology projects currently being worked on, as well as the techniques and assays used within these projects.
Instructors: L. Lee, Dueck
BIO ENG 22L Biotechnology Laboratory 2 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 6 hours of Laboratory per week for 15 weeks.
Prerequisites: 22 (must be taken concurrently).
This course is intended to introduce students to a variety of laboratory techniques that are used in current day biotechnology projects. During this course, students will get hands-on molecular and cellular biotechnology experience working with E. coli, Yeast, Human and Mouse Cell Lines, DNA, RNA, and proteins. This is a bioengineering course; the focus of these exercises will be on the critical understanding of biological, biochemical, or physical mechanisms, and theories of different experiemental methods, techniques, and instrumentation used. Second, students leaving this class should understand how to address a critical biological question and design experiments in a quantitative manner.
Instructors: L. Lee, Dueck
BIO ENG 24 Aspects of Bioengineering 1 Unit
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall and spring
Grading: Offered for pass/not pass grade only.
Hours and format: 1 hour of Seminar per week for 15 weeks.
This introductory seminar is designed to give freshmen and sophomores a glimpse of a broad selection of bioengineering research that is currently underway at Berkeley and UCSF. Students will become familiar with bioengineering applications in the various concentration areas and see how engineering principles can be applied to biological and medical problems.
Course may be repeated for credit when topic changes.
BIO ENG 25 Careers in Biotechnology 1 Unit
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Offered for pass/not pass grade only.
Hours and format: 1 hour of Seminar per week for 15 weeks.
This introductory seminar is designed to give freshmen and sophomores an opportunity to explore specialties related to engineering in the pharmaceutical/biotech field. A series of one-hour seminars will be presented by industry professionals, professors, and researchers. Topics may include biotechnology and pharmaceutical manufacturing; process and control engineering; drug inspection process; research and development; compliance and validation; construction process for a GMP facility; project management; and engineered solutions to environmental challenges. This course is of interest to students in all areas of engineering and biology, including industrial engineering and manufacturing, chemical engineering, and bioengineering.
Course may be repeated for credit. Course may be repeated for credit when topic changes.
BIO ENG 84 Sophomore Seminar 1 or 2 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: The grading option will be decided by the instructor when the class is offered.
Hours and format: 1 hour of seminar per week per unit for 15 weeks. 1 and 1 half hours of seminar per week per unit for 10 weeks. 2 hours of seminar per week per unit for 8 weeks. 3 hours of seminar per week per unit for 5 weeks.
Prerequisites: At discretion of instructor.
Sophomore seminars are small interactive courses offered by faculty members in departments all across the campus. Sophomore seminars offer opportunity for close, regular intellectual contact between faculty members and students in the crucial second year. The topics vary from department to department and semester to semester. Enrollment limited to 15 sophomores.
Course may be repeated for credit as topic varies. Course may be repeated for credit when topic changes.
BIO ENG 98 Supervised Independent Group Studies 1 - 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Offered for pass/not pass grade only.
Hours and format: Group study meetings.
Prerequisites: Consent of instructor.
Organized group study on various topics under the sponsorship of a member of the Bioengineering faculty.
Course may be repeated for credit. Course may be repeated for credit when topic changes. Enrollment is restricted; see the Introduction to Courses and Curricul a section of this catalog.
BIO ENG 99 Supervised Independent Study and Research 1 - 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Offered for pass/not pass grade only.
Hours and format: 1 to 4 hour of Independent study per week for 15 weeks. 1.5 to 6 hours of Independent study per week for 10 weeks. 1.5 to 7.5 hours of Independent study per week for 8 weeks.
Prerequisites: Freshman or sophomore standing and consent of instructor.
Supervised independent study for lower division students.
Course may be repeated for credit. Course may be repeated for credit when topic changes. Enrollment is restricted; see the Introduction to Courses and Curricula section of this catalog.
BIO ENG 100 Ethics in Science and Engineering 3 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Spring and summer
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks. 4.5 hours of Lecture per week for 10 weeks. 5.5 hours of Lecture per week for 8 weeks. 7.5 hours of Lecture per week for 6 weeks.
The goal of this semester course is to present the issues of professional conduct in the practice of engineering, research, publication, public and private disclosures, and in managing professional and financial conflicts. The method is through historical didactic presentations, case studies, presentations of methods for problem solving in ethical matters, and classroom debates on contemporary ethical issues. The faculty will be drawn from national experts and faculty from religious studies, journalism, and law from the UC Berkeley campus.
Instructor: Head-Gordon
BIO ENG 101 Instrumentation in Biology and Medicine 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of lecture and 3 hours of discussion/computer laboratory per week.
Prerequisites: Electrical Engineering 100, Mathematics 53, 54, Physics 7A-7B, or consent of instructor.
This course teaches the fundamental principles underlying modern sensing and control instrumentation used in biology and medicine. The course takes an integrative analytic and hands-on approach to measurement theory and practice by presenting and analyzing example instruments currently used for biology and medical research, including EEG, ECG, pulsed oximeters, Complete Blood Count (CBC), etc.
Instructor: Conolly
BIO ENG 102 Biomechanics: Analysis and Design 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of lecture and 1 hour of discussion per week.
Prerequisites: Math 53, 54; Physics 7A.
This course introduces, develops and applies the methods of continuum mechanics to biomechanical phenomena abundant in biology and medicine. It is intended for upper level undergraduate students who have been exposed to vectors, differential equations, and undergraduate course(s) in physics and certain aspects of modern biology.
Course Objectives: This course introduces, develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena related to tissue or organ levels. It is intended for upper level undergraduate students who have been exposed to vectors, differential equations, and undergraduate course(s) in physics and certain aspects of modern biology.
Topics include:
• Biosolid mechanics
• Stress, strain, constitutive equation
• Vector and tensor math
• Equilibrium
• Extension, torsion, bending, buckling
• Material properties of tissues
Student Learning Outcomes: The course will equip the students with a deep understanding of principles of biomechanics. The intuitions gained in this course will help guide the analysis of design of biomedical devices and help the understanding of biological/medical phenomena in health and disease.^The students will develop insight, skills and tools in quantitative analysis of diverse biomechanical systems and topics, spanning various scales from cellular to tissue and organ levels.
Instructor: Mofrad
BIO ENG 104 Biological Transport Phenomena 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.
Prerequisites: Mathematics 53, 54, and Physics 7A.
The transport of mass, momentum, and energy are critical to the function of living systems and the design of medical devices. Biological transport phenomena are present at a wide range of length scales: molecular, cellular, organ (whole and by functional unit), and organism. This course develops and applies scaling laws and the methods of continuum mechanics to biological transport phenomena over a range of length and time scales. The course is intended for undergraduate students who have taken a course in differential equations and an introductory course in physics. Students should be familiar with basic biology; an understanding of physiology is useful, but not assumed.
Instructor: Johnson
BIO ENG 110 Biomedical Physiology for Engineers 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: 10, Biology 1A; Math 54 (may be taken concurrently).
This course introduces students to the physiology of human organ systems, with an emphasis on quantitative problem solving, engineering-style modeling, and applications to clinical medicine. The course will begin with a review of basic principles of cellular physiology, including membrane transport and electrophysiology, and then take a system-by-system approach to the physiology of various organ systems, including the cardiovascular, pulmonary, renal, and endocrine systems. Throughout, the course will feature extensive discussions of clinical conditions associated with dysfunction in specific physiological processes as well as the role of medical devices and prostheses. This course is geared towards upper-division bioengineering students who wish to solidify their foundation in physiology, especially in preparation for a career in clinical medicine or the biomedical device industry.
Instructor: Kumar
BIO ENG 111 Functional Biomaterials Development and Characterization 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Chemistry 1A or 4A, Biology 1A and 1AL, Molecular and Cell Biology C100A/Chemistry C130 or Molecular Cell Biology 102.
This course is intended for upper level engineering undergraduate students interested in the development of novel functional proteins and peptide motifs and characterization of their physical and biological properties using various instrumentation tools in quantitative manners.
Instructor: SW Lee
BIO ENG 112 Molecular Cell Biomechanics 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Mathematics 54, Physics 7A, 102, or consent of instructors.
This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular levels. It is intended for senior undergraduate students who have been exposed to differential equations, mechanics, and certain aspects of modern biology.
Instructor: Mofrad
BIO ENG C112/MEC ENG C115 Molecular Cell Biomechanics 4 Units
Department: Bioengineering; Mechanical Engineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.
This course applies methods of statistical continuum mechanics to subcellar biomechanical phenomena ranging from nanoscale (molecular) to microscale (whole cell and cell population) biological processes at the interface of mechanics, biology, and chemistry.
Instructor: Mofrad
BIO ENG 113 Stem Cells and Technologies 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: 10 and Biology 1A, or consent of instructor.
This course will teach the main concepts and current views on key attributes of embryonic stem cells (ESC), will introduce theory of their function in embryonic development, methods of ESC derivation, propagation, and characterization, and will discuss currently developing stem cell technologies.
Instructor: Conboy
BIO ENG 115 Cell Biology for Engineers 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 6 hours of Laboratory per week for 15 weeks. 3 hours of Lecture and 9 hours of Laboratory per week for 10 weeks. 3.5 hours of Lecture and 11 hours of Laboratory per week for 8 weeks. 5 hours of Lecture and 15 hours of Laboratory per week for 6 weeks.
Prerequisites: Chemistry C130/Molecular Cell Biology C100A or equivalent recommended.
The structural and functional characteristics of tissues are altered by cells in response to culture conditions, loading, injury, and various other factors. A contemporary understanding of the form, function, and longevity of tissues includes knowledge of tissue microstructure, composition of matrix, and cell function. Students will be introduced to molecular biology techniques as applied to cells and tissues including immunofluorescence, image analysis, protein quantification, gene expression, and cell culture.
Instructor: Johnson
BIO ENG 116 Cell and Tissue Engineering 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: 102 and Chemistry C130/Molecular and Cell Biology C100A or equivalent recommended, or consent of instructor.
The goal of tissue engineering is to fabricate substitutes to restore tissue structure and functions. Understanding cell function in response to environmental cues will help us to establish design criteria and develop engineering tools for tissue fabrication. This course will introduce the basic concepts and approaches in the field, and train students to design and engineer biological substitutes. Lectures will be based on the textbook, the reference books and recent literature. Discussion sections will include the discussion of current literature and issues related to course content, homework, exams, and projects. Homework includes quantitative analysis, essay questions, and literature research. There will be a midterm exam, final exam, and a design project (presentation and paper). The final project will be a group project (three to four students) or independent project (required for graduate students). The topic will be chosen by each group and approved by instructor/GSIs.
Instructor: Li
BIO ENG C117/MEC ENG C117 Structural Aspects of Biomaterials 4 Units
Department: Bioengineering; Mechanical Engineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 2 hours of Laboratory per week for 15 weeks.
Prerequisites: Biology 1A, Engineering 45, Civil and Environmental Engineering 130 or 130N or Bioengineering 102, and Engineering 190.
This course covers the structure and mechanical functions of load bearing tissues and their replacements. Natural and synthetic load-bearing biomaterials for clinical applications are reviewed. Biocompatibility of biomaterials and host response to structural implants are examined. Quantitative treatment of biomechanical issues and constitutive relationships of tissues are covered in order to design biomaterial replacements for structural function. Material selection for load bearing applications including reconstructive surgery, orthopedics, dentistry, and cardiology are addressed. Mechanical design for longevity including topics of fatigue, wear, and fracture are reviewed. Case studies that examine failures of devices are presented. This course includes a teaching/design laboratory component that involves design analysis of medical devices and outreach teaching to the public community. Several problem-based projects are utilized throughout the semester for design analysis. In addition to technical content, this course involves rigorous technical writing assignments, oral communication skill development and teamwork.
Instructor: Pruitt
BIO ENG C118/MAT SCI C118 Biological Performance of Materials 4 Units
Department: Bioengineering; Materials Science and Engineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Molecular and Cell Biology 102, 130 (recommended), and Engineering 45, 115 or equivalent.
This course is intended to give students the opportunity to expand their knowledge of topics related to biomedical materials selection and design. Structure-property relationships of biomedical materials and their interaction with biological systems will be addressed. Applications of the concepts developed include blood-materials compatibility, biomimetic materials, hard and soft tissue-materials interactions, drug delivery, tissue engineering, and biotechnology.
Instructor: Healy
BIO ENG C119/MEC ENG C176 Orthopedic Biomechanics 4 Units
Department: Bioengineering; Mechanical Engineering
Course level: Undergraduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 3 hours of lecture and 1 hour of discussion/computer workshop per week.
Prerequisites: Civil and Environmental Engineering 130 or 130N.
Statics, dynamics, optimization theory, composite beam theory, beam-on-elastic foundation theory, Hertz contact theory, and materials behavior. Forces and moments acting on human joints; composition and mechanical behavior of orthopedic biomaterials; design/analysis of artificial joint, spine, and fracture fixation prostheses; musculoskeletal tissues including bone, cartilage, tendon, ligament, and muscle; osteoporosis and fracture-risk predication of bones; and bone adaptation. MATLAB-based project to integrate the course material.
Instructor: Keaveny
BIO ENG 121 BioMEMS and Medical Devices 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks. 4.5 hours of Lecture per week for 10 weeks. 5.5 hours of Lecture per week for 8 weeks. 7.5 hours of Lecture per week for 6 weeks.
Prerequisites: Chemistry 3A; Physics 7A and 7B.
Biophysical and chemical principles of biomedical devices, bionanotechnology, bionanophotonics, and biomedical microelectromechanical systems (BioMEMS). Topics include basics of nano- and microfabrication, soft-lithography, DNA arrays, protein arrays, electrokinetics, electrochemical, transducers, microfluidic devices, biosensor, point of care diagnostics, lab-on-a-chip, drug delivery microsystems, clinical lab-on-a-chip, advanced biomolecular probes, etc.
Instructor: L. Lee
BIO ENG 121L BioMems and BioNanotechnology Laboratory 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 6 hours of Laboratory and 2 hours of Lecture per week for 15 weeks.
Prerequisites: 102 or 104; 22/22L or Molecular and Cell Biology C100A/Chemistry C130 or equivalent.
Students will become familiar with BioMEMS and Lab-on-a-Chip research. Students will design and fabricate their own novel micro- or nano-scale device to address a specific problem in biotechnology using the latest micro- and nano-technological tools and fabrication techniques. This will involve an intensive primary literature review, experimental design, and quantitative data analysis. Results will be presented during class presentations and at a final poster symposium.
Students will receive no credit for 121L after taking 221L. Instructors: L. Lee, Dueck
BIO ENG C125/EL ENG C125 Introduction to Robotics 4 Units
Department: Bioengineering; Electrical Engineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture, 1 hour of Discussion, and 3 hours of Laboratory per week for 15 weeks.
Prerequisites: 120 or equivalent, consent of instructor.
An introduction to the kinematics, dynamics, and control of robot manipulators, robotic vision, and sensing. The course covers forward and inverse kinematics of serial chain manipulators, the manipulator Jacobian, force relations, dynamics, and control. It presents elementary principles on proximity, tactile, and force sensing, vision sensors, camera calibration, stereo construction, and motion detection. The course concludes with current applications of robotics in active perception, medical robotics, and other areas.
Instructor: Bajcsy
BIO ENG 131 Introduction to Computational Molecular and Cell Biology 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Mathematics 53 and Biology 1A (may be taken concurrently).
Topics include computational approaches and techniques to gene structure and genome annotation, sequence alignment using dynamic programming, protein domain analysis, RNA folding and structure prediction, RNA sequence design for synthetic biology, genetic and biochemical pathways and networks, UNIX and scripting languages, basic probability and information theory. Various "case studies" in these areas are reviewed; web-based computational biology tools will be used by students and programming projects will be given. Computational biology research connections to biotechnology will be explored.
Students will receive no credit for 131 after taking 231. Instructor: Holmes
BIO ENG 132 Genetic Devices 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Engineering 7 or Computer Science 61A, Mathematics 54, Chemistry 3A, and Chemistry C130/Molecular and Cell Biology C100A.
This senior-level course is a comprehensive survey of genetic devices. These DNA-based constructs are comprised of multiple "parts" that together encode a higher-level biological behavior and perform useful human-defined functions. Such constructs are the engineering target for most projects in synthetic biology. Included within this class of constructs are genetic circuits, sensors, biosynthetic pathways, and microbiological functions.
Students will receive no credit for 132 after taking 232. Instructor: Anderson
BIO ENG 135 Frontiers in Microbial Systems Biology 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Upper division standing with background in differential equations and probability. Coursework in molecular and cell biology or biochemistry recommended.
This course is aimed at graduate and advanced undergraduate students from the (bio) engineering and chemo-physical sciences interested in a research-oriented introduction to current topics in systems biology. Focusing mainly on two well studied microbiological model systems--the chemotaxis network and Lambda bacteriophage infection--the class systematically introduces key concepts and techniques for biological network deduction, modelling, analysis, evolution, and synthetic network design. Students analyze the impact of approaches from the quantitative sciences--such as deterministic modelling, stochastic processes, statistics, non-linear dynamics, control theory, information theory, graph theory, etc.--on understanding biological processes, including (stochastic) gene regulation, signalling, network evolution, and synthetic network design. The course aims to identify unsolved problems and discusses possible novel approaches while encouraging students to develop ideas to explore new directions in their own research.
Students will receive no credit for 135 after taking 235. Instructors: Arkin, Bischofs-Pfeifer, Wolf
BIO ENG C136L/EL ENG C145O/INTEGBI C135L Laboratory in the Mechanics of Organisms 3 Units
Department: Bioengineering; Electrical Engineering; Integrative Biology
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 6 hours of laboratory and 1 hour of discussion per week, plus 1 field trip.
Prerequisites: Integrative Biology 135 or consent of instructor; for Electrical Engineering and Computer Science students, Electrical Engineering 105, 120 or Computer Science 184.
Introduction to laboratory and field study of the biomechanics of animals and plants using fundamental biomechanical techniques and equipment. Course has a series of rotations involving students in experiments demonstrating how solid and fluid mechanics can be used to discover the way in which diverse organisms move and interact with their physical environment. The laboratories emphasize sampling methodology, experimental design, and statistical interpretation of results. Latter third of course devoted to independent research projects. Written reports and class presentation of project results are required.
Students will receive no credit for C135L after taking 135L. Formerly known as Integrative Biology 135L.
BIO ENG 140L Synthetic Biology Laboratory 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 6 hours of Laboratory per week for 15 weeks.
Prerequisites: Molecular biology, basic chemistry and biochemistry, and differential equations; or consent of instructor.
This laboratory course is designed as an introduction to research in synthetic biology, a ground-up approach to genetic engineering with applications in bioenergy, heathcare, materials science, and chemical production. In this course, we will design and execute a real research project. Each student will be responsible for designing and constructing components for the group project and then performing experiments to analyze the system. In addition to laboratory work, we will have lectures on methods and design concepts in synthetic biology including an introduction to Biobricks, gene synthesis, computer modeling, directed evolution, practical molecular biology, and biochemistry.
Instructor: Anderson
BIO ENG 143 Computational Methods in Biology 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture, 2 hours of Laboratory, and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Math 53 and Math 54; programming experience preferred but not required.
An introduction to biophysical simulation methods and algorithms, including molecular dynamics, Monte Carlo, mathematical optimization, and "non-algorithmic" computation such as neural networks. Various case studies in applying these areas in the areas of protein folding, protein structure prediction, drug docking, and enzymatics will be covered. Core Specialization: Core B (Informatics and Genomics); Core D (Computational Biology); BioE Content: Biological.
Instructor: Head-Gordon
BIO ENG C144/PLANTBI C144 Introduction to Protein Informatics 4 Units
Department: Bioengineering; Plant and Microbial Biology
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
This course will introduce students to the fundamentals of molecular biology, and to the bioinformatics tools and databases used for the prediction of protein function and structure. It is designed to impart both a theoretical understanding of popular computational methods, as well as some experience with protein sequence analysis methods applied to real data. This class includes no programming, and no programming background is required.
Instructor: Sjolander
BIO ENG C144L/PLANTBI C144L Protein Informatics Laboratory 2 Units
Department: Bioengineering; Plant and Microbial Biology
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 6 hours of Laboratory per week for 15 weeks.
This course is intended to introduce students to a variety of bioinformatics techniques that are used to predict protein function and structure. It is designed to be taken concurrently with C144 (which provides the theoretical foundations for the methods used in the laboratory class), although students can petition to take this laboratory course separately. No programming is performed in this class, and no prior programming experience is required.
Instructor: Sjolander
BIO ENG C145L/EL ENG C145L Introductory Electronic Transducers Laboratory 3 Units
Department: Bioengineering; Electrical Engineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.
Laboratory exercises exploring a variety of electronic transducers for measuring physical quantities such as temperature, force, displacement, sound, light, ionic potential; the use of circuits for low-level differential amplification and analog signal processing; and the use of microcomputers for digital sampling and display. Lectures cover principles explored in the laboratory exercises; construction, response and signal to noise of electronic transducers and actuators; and design of circuits for sensing and controlling physical quantities.
Instructor: Derenzo
BIO ENG C145M/EL ENG C145M Introductory Microcomputer Interfacing Laboratory 3 Units
Department: Bioengineering; Electrical Engineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.
Prerequisites: 40, Compsci 61B or a working knowledge of ANSI C programming or consent of instructor.
Laboratory exercises constructing basic interfacing circuits and writing 20-100 line C programs for data acquisition, storage, analysis, display, and control. Use of the IBM PC with microprogrammable digital counter/timer, parallel I/O port. Circuit components include anti-aliasing filters, the S/H amplifier, A/D and D/A converters. Exercises include effects of aliasing in periodic sampling, fast Fourier transforms of basic waveforms, the use of the Hanning filter for leakage reduction, Fourier analysis of the human voice, digital filters, and control using Fourier deconvolution. Lectures cover principles explored in the lab exercises and design of microcomputer-based systems for data acquisitions, analysis and control.
Instructor: Derenzo
BIO ENG 147 Principles of Synthetic Biology 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Math 53 and 54; Molecular and Cell Biology C100A/Chemistry C130; or consent of instructor.
The field of synthetic biology is quickly emerging as potentially one of the most important and profound ways by which we can understand and manipulate our physical world for desired purposes. In this course, the field and its natural scientific and engineering basis are introduced. Relevant topics in cellular and molecular biology and biophysics, dynamical and engineering systems, and design and operation of natural and synthetic circuits are covered in a concise manner that then allows the student to begin to design new biology-based systems.
Students will receive no credit for 147 after taking 247. Instructor: Arkin
BIO ENG 148 Bioenergy and Sustainable Chemical Synthesis: Metabolic Engineering and Synthetic Biology Approaches 3 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of lecture per week.
Prerequisites: Chemistry 3A and Molecular and Cell Biology C100A/Chemistry C130A or equivalent.
This course will cover metabolic engineering and the various synthetic biology approaches for optimizing pathway performance. Use of metabolic engineering to produce biofuels and general "green technology" will be emphasized since these aims are currently pushing these fields. The course is meant to be a practical guide for metabolic engineering and the related advances in synthetic biology as well the related industrial research and opportunities.
Course Objectives: (1) Learn the common engineered metabolic pathways for biofuel biosynthesis
(2) analytical methods
(3) synthetic biology approaches
(4) Industry technologies and opportunities
Student Learning Outcomes: Students will learn (1) the common pathways used for biofuel synthesis and framework for the biosynthesis of specialty chemicals, (2) analytical methods for quantitative measurements of metabolic pathways, (3) synthetic biology approaches for increasing overall pathway performance, and how to (4) utilize available online resources for culling information from large data sources.
Instructor: Dueber
BIO ENG 150 Introduction of Bionanoscience and Bionanotechnology 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Biology 1A and Chemistry 1A.
This course is intended for the bioengineering or engineering undergraduate students interested in acquiring a background in recent development of bio-nanomaterials and bio-nanotechnology. The emphasis of the class is to understand the properties of biological basis building blocks, their assembly principles in nature, and their application to build functional materials and devices. The goal is for the bioengineering students to gain sufficient chemical and physical aspects of biological materials through the case study of spider webs, silks, sea shells, diatoms, bones, and teeth, as well as recently developed self-assembled nanostructures inspired by nature. The course covers the structures and properties of amino acids, DNAs, sugars, lipids, and their natural and artifical assembly structures. It also covers nanoscale inorganic materials used to develop nano medicines, bio-imaging, bio-sensors, bioelectronics, and machinery.
Instructor: S. W. Lee
BIO ENG 151 Micro/Nanofluidics for Bioengineering and Lab-On-A-Chip 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Chemistry 3B, Physics 7B, Bioengineering 102 or Mechanical Engineering 106 or consent of instructor.
Introduction and in-depth treatment of theory relevant to fluid flow in microfluidic and nanofluidic systems supplemented by critical assessment of recent applications drawn from the literature. Topics include low Reynolds Number flow, mass transport including diffusion phenomena, and emphasis on electrokinetic systems and bioanalytical applications of said phenomena.
Students will receive no credit for 151 after taking 251. Instructor: Herr
BIO ENG 163 Principles of Molecular and Cellular Biophotonics 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: 102 or consent of instructor, Chemistry 3A, and Physics 7B.
This course provides undergraduate and graduate bioengineering students with an opportunity to increase their knowledge of topics in the emerging field of biophotonics with an emphasis on fluorescence spectroscopy, biosensors and devices for optical imaging and detection of biomolecules. This course will cover the photophysics and photochemistry of organic molecules, the design and characterization of biosensors and their applications within diverse environments.
Instructor: Marriott
BIO ENG 163L Molecular and Cellular Biophotonics Laboratory 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 6 hours of Laboratory and 2 hours of Discussion per week for 15 weeks.
Prerequisites: Bioengineering 163L; experience in a research lab and consent of instructor.
This course provides undergraduate and graduate bioengineering students with an opportunity to acquire essential experimental skills in fluorescence spectroscopy and the design, evaluation, and optimization of optical biosensors for quantitative measurements of proteins and their targets. Groups of students will be responsible for the research, design, and development of a biosensor or diagnostic device for the detection, diagnosis, and monitoring of a specific biomarker(s).
Students will receive no credit for Bioengineering 163L after taking Bioengineering 263L. Instructor: Marriott
BIO ENG 164 Optics and Microscopy 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Physics 7A-7B or 8A-8B or equivalent introductory physics course.
This course teaches fundamental principles of optics and examines contemporary methods of optical microscopy for cells and molecules. Students will learn how to design simple optical systems, calculate system performance, and apply imaging techniques including transmission, reflection, phase, and fluorescence microscopy to investigate biological samples. The capabilities of optical microscopy will be compared with complementary techniques including electron microscopy, coherence tomography, and atomic force microscopy. Students will also be responsible for researching their final project outside of class and presenting a specific application of modern microscopy to biological research as part of an end-of-semester project.
Instructor: Fletcher
BIO ENG C165/EL ENG C145B Medical Imaging Signals and Systems 4 Units
Department: Bioengineering; Electrical Engineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Electrical Engineering 120; basic programming ability in C or FORTRAN.
Biomedical imaging is a clinically important application of engineering, applied mathematics, physics, and medicine. In this course, we apply linear systems theory and basic physics to analyze X-ray imaging, computerized tomography, nuclear medicine, and MRI. We cover the basic physics and instrumentation that characterizes medical image as an ideal perfect-resolution image blurred by an impulse response. This material could prepare the student for a career in designing new medical imaging systems that reliably detect small tumors or infarcts.
Instructor: Conolly
BIO ENG 168L Practical Light Microscopy 3 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.
This laboratory course is designed for students interested in obtaining practical hands-on training in optical imaging and instrumentation. Using a combination of lenses, cameras, and data acquisition equipment, students will construct simple light microscopes that introduce basic concepts and limitations important in biomedical optical imaging. Topics include compound microscopes, Kohler illumination, Rayleigh two-point resolution, image contrast including dark-field and fluorescence microscopy, and specialized techniques such as fluorescence recovery after photobleaching (FRAP). Intended for students in both engineering and the sciences, this course will emphasize applied aspects of optical imaging and provide a base of practical skill and reference material that students can leverage in their own research or in industry.
Instructor: Fletcher
BIO ENG C181/CHEM C138/CHM ENG C195A/PLANTBI C124 The Berkeley Lectures on Energy: Energy from Biomass 3 Units
Department: Bioengineering; Chemical & Biomolecular Engineering; Chemistry; Plant and Microbial Biology
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Chemistry 1B or Chemistry 4B, Mathematics 1B, Biology 1A.
After an introduction to the different aspects of our global energy consumption, the course will focus on the role of biomass. The course will illustrate how the global scale of energy guides the biomass research. Emphasis will be placed on the integration of the biological aspects (crop selection, harvesting, storage and distribution, and chemical composition of biomass) with the chemical aspects to convert biomass to energy. The course aims to engage students in state-of-the-art research.
Repeatable when topic changes with consent of instructor. Instructors: Bell, Blanch, Clark, Smit, C. Somerville
BIO ENG 190D Advanced Topics in Bioengineering: Advanced Topics in Computational Bioengineering 1 - 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Letter grade.
Hours and format: 1 to 4 hour of Lecture per week for 15 weeks. 1.5 to 6 hours of Lecture per week for 10 weeks. 1.5 to 7.5 hours of Lecture per week for 8 weeks. 2.5 to 10 hours of Lecture per week for 6 weeks.
These courses cover current topics of research interest in bioengineering. The course content may vary from semester to semester.
Course may be repeated for credit when topic changes.
BIO ENG 190H Advanced Topics in Bioengineering: Advanced Topics in Biomedical Systems Engineering 1 - 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: The grading option will be decided by the instructor when the class is offered.
Hours and format: 1 to 4 hour of Lecture per week for 15 weeks. 1.5 to 6 hours of Lecture per week for 10 weeks. 1.5 to 7.5 hours of Lecture per week for 8 weeks. 2.5 to 10 hours of Lecture per week for 6 weeks.
These courses cover current topics of research interest in bioengineering. The course content may vary from semester to semester.
Course may be repeated for credit when topic changes.
BIO ENG 192 Senior Design Projects 4 Units
Department: Bioengineering
Course level: Undergraduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 2 hours of Discussion per week for 15 weeks.
Prerequisites: Senior standing.
This semester-long course introduces students to bioengineering project-based learning in small teams, with a strong emphasis on need-based solutions for real medical and research problems through prototype solution selection, design, and testing. The course is designed to provide a "capstone" design experience for bioengineering seniors. The course is structured around didactic lectures, and a textbook, from which assigned readings will be drawn, and supplemented by additional handouts, readings, and lecture material. Where appropriate, the syllabus includes guest lectures from clinicians and practicing engineers from academia and industry. The course includes active learning through organized activities, during which teams will participate in exercises meant to reinforce lecture material through direct application to the team design project.
Instructor: Herr
BIO ENG H194 Honors Undergraduate Research 3 or 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Letter grade.
Hours and format: Variable format.
Prerequisites: Upper division technical GPA 3.3 or higher and consent of instructor and adviser.
Supervised research. Students who have completed 3 or more upper division courses may pursue original research under the direction of one of the members of the staff. May be taken a second time for credit only. A final report or presentation is required. A maximum of 4 units of this course may be used to fulfill the research or technical elective requirement or in the Bioengineering program.
Course may be repeated for a maximum of 8 units.Course may be repeated for a maximum of 8 units.
BIO ENG 196 Undergraduate Design Research 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Letter grade.
Hours and format: Individual research.
Prerequisites: Junior or senior status, consent of instructor and faculty adviser.
Supervised research. This course will satisfy the Senior Bioengineering Design project requirement. Students with junior or senior status may pursue research under the direction of one of the members of the staff. May be taken a second time for credit only. A final report or presentation is required.
Course may be repeated for credit once.Course may be repeated for a maximum of 8 units.
BIO ENG 198 Directed Group Study for Advanced Undergraduates 1 - 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Offered for pass/not pass grade only.
Hours and format: 1 to 4 hour of Directed group study per week for 15 weeks. 1.5 to 7.5 hours of Directed group study per week for 8 weeks. 2.5 to 10 hours of Directed group study per week for 6 weeks.
Prerequisites: Upper division standing and good academic standing. (2.0 grade point average and above)
Group study of a selected topic or topics in bioengineering, usually relating to new developments.
Course may be repeated for credit. Course may be repeated for credit when topic changes. Enrollment is restricted; see the Introduction to Courses and Curricula section of this catalog.
BIO ENG 199 Supervised Independent Study 1 - 4 Units
Department: Bioengineering
Course level: Undergraduate
Terms course may be offered: Fall, spring and summer
Grading: Offered for pass/not pass grade only.
Hours and format: Zero hours of Independent study per week for 15 weeks. 1.5 to 6 hours of Independent study per week for 10 weeks. 1.5 to 7.5 hours of Independent study per week for 8 weeks. 2.5 to 10 hours of Independent study per week for 6 weeks.
Supervised independent study.
Course may be repeated for credit. Course may be repeated for credit when topic changes. Enrollment is restricted; see the Introduction to Courses and Curricul a section of this catalog.
BIO ENG 200 The Graduate Group Introductory Seminar 1 Unit
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Offered for satisfactory/unsatisfactory grade only.
Hours and format: 1 hour of Seminar per week for 15 weeks.
Prerequisites: Enrollment in PhD Program in Bioengineering or consent of instructor.
An introduction to research in bioengineering including specific case studies and organization of this rapidly expanding and diverse field.
Course may be repeated for credit. Course may be repeated for credit when topic changes.
BIO ENG C209/MEC ENG C210 Advanced Orthopedic Biomechanics 4 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Prerequisites: ME C85/CE C30 or Bio Eng 102; concurrent enrollment OK. Proficiency in MatLab or equivalent. Prior knowledge of biology or anatomy is not assumed.
Students will learn the application of engineering concepts including statics, dynamics, optimization theory, composite beam theory, beam-on-elastic foundation theory, Hertz contact theory, and materials behavior. Topics will include forces and moments acting on human joints; composition and mechanical behavior of orthopedic biomaterials; design/analysis of artificial joint, spine, and fracture fixation prostheses; musculoskeletal tissues including bone, cartilage, tendon, ligament, and muscle; osteoporosis and fracture-risk predication of bones; and bone adaptation. Students will be challenged in a MATLAB-based project to integrate the course material in an attempt to gain insight into contemporary design/analysis/problems.
Course Objectives: The purpose of this course is twofold:
• to learn the fundamental concepts of orthopaedic biomechanics;
• to enhance skills in mechanical engineering and bioengineering by analyzing the mechanical behavior of various complex biomedical problems.
Student Learning Outcomes: Working knowledge of various engineering concepts such as composite beam theory, beam-on-elastic-foundation theory, Hertz contact theory and MATLAB-based optimization design analysis. Understanding of basic concepts in orthopaedic biomechanics and the ability to apply the appropriate engineering concepts to solve realistic biomechanical problems, knowing clearly the assumptions involved.
Students will not receive credit for this course if they have taken ME C176/Bio E C119. Instructors: O'Connell, Keaveny
BIO ENG 211 Cell and Tissue Mechanotransduction 3 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Undergraduate cell biology or consent of instructor.
This course will focus on biophysical and bioengineering aspects of mechanotransduction, the process through which living cells sense and respond to their mechanical environment. Students will learn how mechanical inputs to cells influence both subcellular biochemistry and whole-cell behavior. They will also study newly-engineered technologies for force manipulation and measurement in living cells, and synthetic strategies to control the mechanics and chemistry of the extracellular matrix. Finally, students will learn about the role of mechanotransduction in selected human organ systems and how these mechanisms may go awry in the setting of the disease. Instruction will feature lectures, discussions, analysis of relevant research papers, assembly of a literature review and a research proposal, and an oral presentation.
Instructor: Kumar
BIO ENG C212/MEC ENG C212 Heat and Mass Transport in Biomedical Engineering 3 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: 106 and 109 (106 and 109 may be taken concurrently).
Fundamental processes of heat and mass transport in biological systems; organic molecules, cells, biological organs, whole animals. Derivation of mathematical models and discussion of experimental procedures. Applications to biomedical engineering.
Formerly known as Mechanical Engineering 212.
BIO ENG C213/MEC ENG C213 Fluid Mechanics of Biological Systems 3 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: 106 or equivalent; 265A or consent of instructor.
Fluid mechanical aspects of various physiological systems, the circulatory, respiratory, and renal systems. Motion in large and small blood vessels. Pulsatile and peristaltic flows. Other biofluidmechanical flows: the ear, eye, etc. Instrumentation for fluid measurements in biological systems and for medical diagnosis and applications. Artificial devices for replacement of organs and/or functions, e.g. blood oxygenators, kidney dialysis machines, artificial hearts/circulatory assist devices.
Instructors: Berger, Liepmann
BIO ENG C214/MEC ENG C214 Advanced Tissue Mechanics 3 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: 102A, 176, 185; graduate standing or consent of instructor.
The goal of this course is to provide a foundation for characterizing and understanding the mechanical behavior of load-bearing tissues. A variety of mechanics topics will be introduced, including anisotropic elasticity and failure, cellular solid theory, biphasic theory, and quasi-linear viscoelasticity (QLV) theory. Building from this theoretical basis, we will explore the constitutive behavior of a wide variety of biological tissues. After taking this course, students should have sufficient background to independently study the mechanical behavior of most biological tissues. Formal discussion section will include a seminar series with external speakers.
BIO ENG C215/MEC ENG C216 Mechanobiology of the Cell: Dynamics of the Cytoskeleton and Nucleus 3 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Open to bioengineering graduate students or consent of instructor.
This course develops and applies scaling laws and the methods of continuum and statistical mechanics to understand micro- and nano-scale mechanobiological phenomena involved in the living cell with particular attention the nucleus and the cytoskelton as well as the interactions of the cell with the extracellular matrix and how these interactions may cause changes in cell architecture and biology, consequently leading to functional adaptation or pathological conditions.
Instructor: Mofrad
BIO ENG C216/MAT SCI C216 Macromolecular Science in Biotechnology and Medicine 4 Units
Department: Bioengineering; Materials Science and Engineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Bioengineering 115 or equivalent; open to seniors with consent of instructor.
Overview of the problems associated with the selection and function of polymers used in biotechnology and medicine. Principles of polymer science, polymer synthesis, and structure-property-performance relationships of polymers. Particular emphasis is placed on the performance of polymers in biological environments. Interactions between macromolecular and biological systems for therapy and diagnosis. Specific applications will include drug delivery, gene therapy, tissue engineering, and surface engineering.
Instructor: Healy
BIO ENG C217/INTEGBI C217/MEC ENG C217 Biomimetic Engineering -- Engineering from Biology 3 Units
Department: Bioengineering; Integrative Biology; Mechanical Engineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Graduate standing in engineering or consent of instructor.
Study of nature's solutions to specific problems with the aim of determining appropriate engineering analogs. Morphology, scaling, and design in organisms applied to engineering structures. Mechanical principles in nature and their application to engineering devices. Mechanical behavior of biological materials as governed by underlying microstructure, with the potential for synthesis into engineered materials. Trade-offs between redundancy and efficiency. Students will work in teams on projects where they will take examples of designs, concepts, and models from biology and determine their potential in specific engineering applications.
Instructor: Dharan
BIO ENG C218/MCELLBI C237 Stem Cells and Directed Organogenesis 3 Units
Department: Bioengineering; Molecular and Cell Biology
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of lecture/laboratory per week.
This course will provide an overview of basic and applied embryonic stem cell (ESC) biology. Topics will include early embryonic development, ESC laboratory methods, biomaterials for directed differentiation and other stem cell manipulations, and clinical uses of stem cells.
Instructor: Conboy
BIO ENG C219/CHM ENG C270 Protein Engineering 3 Units
Department: Bioengineering; Chemical & Biomolecular Engineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
An in-depth study of the current methods used to design and engineer proteins. Emphasis on how strategies can be applied in the laboratory. Relevant case studies presented to illustrate method variations and applications. Intended for graduate students.
Instructor: Tullman-Ercek
BIO ENG 220L Cells and Biomaterials Laboratory 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 2 hours of Lecture and 6 hours of Laboratory per week for 15 weeks.
Prerequisites: Cell and tissue engineering; upper division cell biology course or consent of instructor.
The objective of this course is to teach graduate students the essential laboratory techniques in the design and characterization and analysis of cells and biomaterials. The course will cover basics on synthetic biomaterials and native matrix, cellular responses to biomaterials, three-dimensional culture, and tissue engineering. The course includes a lecture and a laboratory section each week. There will be a midterm exam, final exam, and a tissue engineering group project.
Instructor: Li
BIO ENG 221 Advanced BioMEMS and Bionanotechnology 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks. 4.5 hours of Lecture per week for 10 weeks. 5.5 hours of Lecture per week for 8 weeks. 7.5 hours of Lecture per week for 6 weeks.
Prerequisites: Chemistry 3A, Physics 7A and 7B, Electrical Engineering 143 or equivalent.
Biophysical and chemical principles of biomedical devices, bionanotechnology, bionanophotonics, and biomedical microelectromechanical systems (BioMEMS). Topics include basics of nano-& microfabrication, soft-lithography, DNA arrays, protein arrays, electrokinetics, electrochemical transducers, microfluidic devices, biosensor, point of care diagnostics, lab-on-a-chip, drug delivery microsystems, clinical lab-on-a-chip, advanced biomolecular probes, biomolecular spectroscopy, and etc.
Students will receive no credit for 221 after taking 121. Course may be repeated for credit when topic changes. Instructor: L. Lee
BIO ENG 221L BioMEMS and BioNanotechnology Laboratory 4 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 6 hours of Laboratory and 2 hours of Lecture per week for 15 weeks.
Prerequisites: 102 or 104; 22/22L or Molecular and Cell Biology C100A/Chemistry C130 or equivalent.
Students will become familiar with BioMEMS and Lab-on-a-Chip research. Students will design and fabricate their own novel micro- or nano-scale device to address a specific problem in biotechnology using the latest micro- and nano-technological tools and fabrication techniques. This will involve an intensive primary literature review, experimental design, and quantitative data analysis. Results will be presented during class presentations and at a final poster symposium.
Instructors: Dueck, L. Lee
BIO ENG C222/MEC ENG C215 Advanced Structural Aspects of Biomaterials 4 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 2 hours of Laboratory per week for 15 weeks.
This course covers the structure and mechanical functions of load bearing tissues and their replacements. Biocompatibility of biomaterials and host response to structural implants are examined. Quantitative treatment of biomechanical issues and constitutive relationships of materials are covered in order to design implants for structural function. Material selection for load bearing applications including reconstructive surgery, orthopedics, dentistry, and cardiology are addressed.
BIO ENG C223/MEC ENG C223 Polymer Engineering 3 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Civil Engineering 130, Engineering 45.
A survey of the structure and mechanical properties of advanced engineering polymers. Topics include rubber elasticity, viscoelasticity, mechanical properties, yielding, deformation, and fracture mechanisms of various classes of polymers. The course will discuss degradation schemes of polymers and long-term performance issues. The class will include polymer applications in bioengineering and medicine.
BIO ENG 231 Introduction to Computational Molecular and Cellular Biology 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Topics include computational approaches and techniques to gene structure and genome annotation, sequence alignment using dynamic programming, protein domain analysis, RNA folding and structure prediction, RNA sequence design for synthetic biology, genetic and biochemical pathways and networks, UNIX and scripting languages, basic probability and information theory. Various "case studies" in these areas are reviewed and web-based computational biology tools will be used by students and programming projects will be given.
Students will receive no credit for 231 after taking 131. Instructor: Holmes
BIO ENG 232 Genetic Devices 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Engineering 7 or Computer Science 61A, Mathematics 54, Chemistry 3A, and Chemistry C130/Molecular and Cell Biology C100A.
This graduate-level course is a comprehensive survey of genetic devices. These DNA-based constructs are comprised of multiple "parts" that together encode a higher-level biological behavior and perform useful human-defined functions. Such constructs are the engineering target for most projects in synthetic biology. Included within this class of constructs are genetic circuits, sensors, biosynthetic pathways, and microbiological functions.
Students will receive no credit for 232 after taking 132. Instructor: Anderson
BIO ENG 235 Frontiers in Microbial Systems Biology 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Designed for graduates with background in differential equations and probability. Course work in molecular cell biology or biochemistry helpful.
This course is aimed at graduate and advanced undergraduate students from the (bio) engineering and chemo-physical sciences interested in a research-oriented introduction to current topics in systems biology. Focusing mainly on two well studied microbiological model systems--the chemotaxis network and Lambda bacteriophage infection--the class systematically introduces key concepts and techniques for biological network deduction, modelling, analysis, evolution and synthetic network design. Students analyze the impact of approaches from the quantitative sciences--such as deterministic modelling, stochastic processes, statistics, non-linear dynamics, control theory, information theory, graph theory, etc.--on understanding biological processes, including (stochastic) gene regulation, signalling, network evolution, and synthetic network design. The course aims identify unsolved problems and discusses possible novel approaches while encouraging students to develop ideas to explore new directions in their own research.
Instructors: Arkin, Bischofs-Pfeifer, Wolf
BIO ENG 241 Probabilistic Modeling in Computational Biology 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 3 hours of Laboratory per week for 15 weeks.
Prerequisites: Mathematics 53 and 54 or equivalent; Molecular and Cell Biology C100A/C102 or equivalent; programming class or consent of instructor.
This course reviews the statistical and algorithmic foundations of bioinformatics viewed through the lens of paleogenetics, the science of "Jurassic Park", i.e., the reconstruction of ancient genes and genomes by reverse Bayesian inference under various stochastic models of molecular evolution. Such methods, first proposed in the 1960s by Linus Pauling (and others), are now in reach of practical experimentation due to the falling cost of DNA synthesis technology. Applications of these methods are granting insight into the origin of life and of the human species, and may be powerful tools of synthetic biology. Lectures will review the theoretical content; homework and laboratory exercises will involve writing and applying programs for computational reconstruction of ancient protein and DNA sequences and other measurably evolving entities, both biological (e.g., gene families) and otherwise (e.g., natural language).
Instructor: Holmes
BIO ENG 243 Computational Methods in Biology 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture, 2 hours of Laboratory, and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Mathematics 53 and 54; programming experience preferred but not required.
An introduction to biophysical simulation methods and algorithms, including molecular dynamics, Monte Carlo, mathematical optimization, and "non-algorithmic" computation such as neural networks. Various case studies in applying these areas in the areas of protein folding, protein structure prediction, drug docking, and enzymatics will be covered. Core Specialization: Core B (Informatics and Genomics); Core D (Computational Biology); Bioengineering Content: Biological.
Students will receive no credit for 243 after taking 143. Instructor: Head-Gordon
BIO ENG C244/PLANTBI C244 Introduction to Protein Informatics 4 Units
Department: Bioengineering; Plant and Microbial Biology
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
This course will introduce students to the fundamentals of molecular biology, and to the bioinformatics tools and databases used for the prediction of protein function and structure. It is designed to impart both a theoretical understanding of popular computational methods, as well as some experience with protein sequence analysis methods applied to real data. This class includes no programming, and no programming background required.
Instructor: Sjolander
BIO ENG C244L/PLANTBI C244L Protein Informatics Laboratory 2 Units
Department: Bioengineering; Plant and Microbial Biology
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 6 hours of Laboratory per week for 15 weeks.
This course is intended to introduce students to a variety of bioinformatics techniques that are used to predict protein function and structure. It is designed to be taken concurrently with C244 (which provides the theoretical foundations for the methods used in the laboratory class), although students can petition to take this laboratory course separately. No programming is performed in this class, and no prior programming experience is required.
Instructor: Sjolander
BIO ENG 247 Principles of Synthetic Biology 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Math 53 and 54; Molecular and Cell Biology C100A/Chemistry C130; or consent of instructor.
The field of synthetic biology is quickly emerging as potentially one of the most important and profound ways by which we can understand and manipulate our physical world for desired purposes. In this course, the field and its natural scientific and engineering basis are introduced. Relevant topics in cellular and molecular biology and biophysics, dynamical and engineering systems, and design and operation of natural and synthetic circuits are covered in a concise manner that then allows the student to begin to design new biology-based systems.
Students will receive no credit for 247 after taking 147. Instructor: Arkin
BIO ENG 248 Bioenergy and Sustainable Chemical Synthesis: Metabolic Engineering and Synthetic Biology Approaches 3 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Chemistry 3A and Molecular and Cell Biology C100A/Chemistry C130A or equivalent.
This course will cover metabolic engineering and the various synthetic biology approaches for optimizing pathway performance. Use of metabolic engineering to produce biofuels and general "green technology" will be emphasized since these aims are currently pushing these fields. The course is meant to be a practical guide for metabolic engineering and the related advances in synthetic biology as well the related industrial research and opportunities.
Instructor: Dueber
BIO ENG 251 Micro/Nanofluidics for Bioengineering and Lab-On-A-Chip 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: Chemistry 3B, Physics 7B, Bioengineering 102, or Mechanical Engineering 106 or consent of instructor.
Introduction and in-depth treatment of theory relevant to fluid flow in microfluidic and nanofluidic systems supplemented by critical assessment of recent applications drawn from the literature. Topics include low Reynolds Number flow, mass transport including diffusion phenomena, and emphasis on electrokinetic systems and bioanalytical applications of said phenomena.
Students will receive no credit for 251 after taking 151. Instructor: Herr
BIO ENG 263 Principles of Molecular and Cellular Biophotonics 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture and 1 hour of Discussion per week for 15 weeks.
Prerequisites: 102 or consent of instructor, and Chemistry 3A and Physics 7B.
Topics in the emerging field of biophotonics with an emphasis on fluorescence spectroscopy, biosensors, and devices for optical imaging and detection of biomolecules. The course will cover the photophysics and photochemistry of organic molecules, the design and characterization of biosensors, and their applications within diverse environments, ranging from the detection of single molecules in vitro and in cells to studies of detection, diagnosis, and monitoring of specific health conditions and disease.
Students will receive no credit for 263 after taking 163. Instructor: Marriott
BIO ENG 263L Molecular and Cellular Biophotonics Laboratory 4 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 6 hours of Laboratory and 2 hours of Discussion per week for 15 weeks.
Prerequisites: 263; experience in a research lab and consent of instructor.
This course provides undergraduate and graduate bioengineering students with an opportunity to acquire essential experimental skills in fluorescence spectroscopy and the design, evaluation, and optimization of optical biosensors for quantitative measurements of proteins and their targets. Groups of students will be responsible for the research, design, and development of a biosensor or diagnostic device for the detection, diagnosis, and monitoring of a specific biomarker(s).
Students will receive no credit for 263L after taking 163L. Instructor: Marriott
BIO ENG C265/EL ENG C225E Principles of Magnetic Resonance Imaging 4 Units
Department: Bioengineering; Electrical Engineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 3 hours of lecture and 3 hours of laboratory and 1 hour of discussion per week.
Prerequisites: Either Electrical Engineering 120 or Bioengineering C165/Electrical Engineering C145B or consent of instructor.
Fundamentals of MRI including signal-to-noise ratio, resolution, and contrast as dictated by physics, pulse sequences, and instrumentation. Image reconstruction via 2D FFT methods. Fast imaging reconstruction via convolution-back projection and gridding methods and FFTs. Hardware for modern MRI scanners including main field, gradient fields, RF coils, and shim supplies. Software for MRI including imaging methods such as 2D FT, RARE, SSFP, spiral and echo planar imaging methods.
Course Objectives: Graduate level understanding of physics, hardware, and systems engineering description of image formation, and image reconstruction in MRI. Experience in Imaging with different MR Imaging systems. This course should enable students to begin graduate level research at Berkeley (Neuroscience labs, EECS and Bioengineering), LBNL or at UCSF (Radiology and Bioengineering) at an advanced level and make research-level contribution
Students will receive no credit for Bioengineering C265/El Engineering C225E after taking El Engineering 265. Instructors: Lustig, Conolly
BIO ENG C279/PB HLTH C269C Occupational Biomechanics 4 Units
Department: Bioengineering; Public Health
Course level: Graduate
Term course may be offered: Spring
Grading: Letter grade.
Hours and format: 3 hours of lecture/fieldwork per week.
Overview of ergonomics and occupational biomechanics. Course covers pathophysiology and risk factors of upper extremity and back loading at work, measurement of force and posture, models for risk assessment, anthropometry applied to task and workstation design, tool design, and structure of successful ergonomics programs. Students will conduct a detailed job analysis and design a workplace intervention.
Instructor: Rempel
BIO ENG 280 Ethical and Social Issues in Translational Medicine 1 Unit
Department: Bioengineering
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Prerequisites: Open only to students in the Masters of Translational Medicine Graduate program.
This class is designed to introduce MTM students to their professional responsibilities
as engineers and translational scientists. By the end of it, students will have
experience communicating their ideas appropriately and effectively to their peers,
their superiors, and those whom they manage or mentor. We will also discuss
methods for having a successful graduate school experience - choosing and working
on a project and preparing to meet post-graduate goals. Finally, some of the ethical
challenges likely to be met by a working bioengineer will be explored.
While this syllabus is meant to be an accurate description of the course and its content,
it may be modified at the instructor’s discretion.
Course Objectives: Objectives
? Communications skills and best practices
? Research ethics in translational medicine
? Professional development for MTM graduate students
Student Learning Outcomes: MTM students will become aware of ethical issues commonly confronted in
translational medicine and learn how to evaluate and act accordingly. They will also
leave capable of independently considering new ethical issues that arise during their
careers.
Instructors: Johnson, Terry
BIO ENG C280/MAT SCI C261/NSE C201/PHYSICS C201 Introduction to Nano-Science and Engineering 3 Units
Department: Bioengineering; Materials Science and Engineering; Nanoscale Science and Engineering; Physics
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Major in physical science such as chemistry, physics, etc., or engineering; consent of advisor or instructor.
A three-module introduction to the fundamental topics of Nano-Science and Engineering (NSE) theory and research within chemistry, physics, biology, and engineering. This course includes quantum and solid-state physics; chemical synthesis, growth fabrication, and characterization techniques; structures and properties of semiconductors, polymer, and biomedical materials on nanoscales; and devices based on nanostructures. Students must take this course to satisfy the NSE Designated Emphasis core requirement.
Course may be repeated for credit when topic changes. Instructors: Gronsky, S.W. Lee, Wu
BIO ENG C281/CHEM C238/CHM ENG C295A/PLANTBI C224 The Berkeley Lectures on Energy: Energy from Biomass 3 Units
Department: Bioengineering; Chemical & Biomolecular Engineering; Chemistry; Plant and Microbial Biology
Course level: Graduate
Term course may be offered: Fall
Grading: Letter grade.
Hours and format: 3 hours of Lecture per week for 15 weeks.
Prerequisites: Biology 1A; Chemistry 1B or 4B, Mathematics 1B.
After an introduction to the different aspects of our global energy consumption, the course will focus on the role of biomass. The course will illustrate how the global scale of energy guides the biomass research. Emphasis will be places on the integration of the biological aspects (crop selection, harvesting, storage, and distribution, and chemical composition of biomass) with the chemical aspects to convert biomass to energy. The course aims to engage students in state-of-art research.
Repeatable when topic changes with consent of instructor. Instructors: Bell, Blanch, Clark, Smit, C. Somerville
BIO ENG 290A Advanced Topics in Bioengineering: Advanced Topics in Biomechanics and Tissue Engineering 1 - 3 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 1 to 3 hour of Lecture per week for 15 weeks.
This course covers current topics of research interest in bioengineering. The course content may vary from semester to semester.
Course may be repeated for credit when topic changes. One hour of lecture per week per unit.
BIO ENG C290D/MEC ENG C290X Advanced Technical Communication: Proposals, Patents, and Presentations 3 Units
Department: Bioengineering; Mechanical Engineering
Course level: Graduate
Term course may be offered: Spring
Grading: Offered for satisfactory/unsatisfactory grade only.
Hours and format: 3 hours of Lecture per week for 15 weeks.
This course will help the advanced Ph.D. student further develop critically important technical communication traits via a series of lectures, interactive workshops, and student projects that will address the structure and creation of effective research papers, technical reports, patents, proposals, business plans, and oral presentations. One key concept will be the emphasis on focus and clarity--achieved through critical thinking regarding objectives and context. Examples will be drawn primarily from health care and bioengineering multidisciplinary applications.
Instructors: Keaveny, Pruitt
BIO ENG 290D Advanced Topics in Bioengineering: Advanced Topics in Computational Bioengineering 1 - 3 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 1 to 3 hour of Lecture per week for 15 weeks.
This course covers current topics of research interest in bioengineering. The course content may vary from semester to semester.
Course may be repeated for credit when topic changes. One hour of lecture per week per unit.
BIO ENG 290H Advanced Topics in Bioengineering: Advanced Topics in Biomedical Systems Engineering 1 - 3 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Hours and format: 1 to 3 hour of Lecture per week for 15 weeks.
This course covers current topics of research interest in bioengineering. The course content may vary from semester to semester.
Course may be repeated for credit when topic changes. One hour of lecture per week per unit.
BIO ENG 290I Advanced Topics in Bioengineering: Advanced Topics in Special Topics in Bioengineering 1 - 3 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall, spring and summer
Grading: Letter grade.
Hours and format: 1 to 3 hour of Lecture per week for 15 weeks. 1.5 to 4.5 hours of Lecture per week for 10 weeks. 1.5 to 5.5 hours of Lecture per week for 8 weeks. 2.5 to 7.5 hours of Lecture per week for 6 weeks.
This course covers current topics of research interest in bioengineering. The course content may vary from semester to semester.
Course may be repeated for credit when topic changes. One hour of lecture per week per unit.
BIO ENG 296 MTM Capstone Project 3 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Letter grade.
Prerequisites: Graduate status in the MTM program
Members of the MTM Program Committee will help design several capstone projects in collaboration with clinical, academic, and/or industry partners, aiming to incorporate emerging technologies, industry requirements, and the potential for significant economic or social impact with regard to medicine and health care. All projects will be designed and vetted by the MTM Program Committee and in consultation with the MTM Advisory Board. For each selected project, an Academic Senate member from the Department of Bioengineering or BTS will serve as research adviser.
Course Objectives: The objective of the one year professional MTM program is to develop engineering leaders who can synthesize the technical, environmental, economic, and social issues involved in the design and operation of complex engineering devices, systems, and organizations. Students will develop and demonstrate this skill at synthesis through the capstone project.
Student Learning Outcomes: Projects will provide practical instruction and experience in solving real problems in translational medicine, and it is anticipated that some will lead to innovations with commercial potential. This experience, undertaken by each student as a member of a team and marked by extensive interaction with faculty, peers, and industry partners, enables the student to integrate the leadership and technical dimensions of the professional MTM curriculum.
Course may be repeated for credit when topic changes. Instructors: Li, Song
BIO ENG 298 Group Studies, Seminars, or Group Research 1 - 8 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Offered for satisfactory/unsatisfactory grade only.
Hours and format: 1 to 8 hour of Directed group study per week for 15 weeks.
Advanced studies in various subjects through special seminars on topics to be selected each year. Informal group studies of special problems, group participation in comprehensive design problems, or group research on complete problems for analysis and experimentation.
Course may be repeated for credit. Course may be repeated for credit when topic changes.
BIO ENG 299 Individual Study or Research 1 - 12 Units
Department: Bioengineering
Course level: Graduate
Terms course may be offered: Fall and spring
Grading: Offered for satisfactory/unsatisfactory grade only.
Hours and format: Zero hours of Independent study per week for 15 weeks.
Prerequisites: Graduate standing.
Investigations of advanced problems in bioengineering.
Course may be repeated for credit. Course may be repeated for credit when topic changes.
BIO ENG N299 Individual Study or Research 1 - 6 Units
Department: Bioengineering
Course level: Graduate
Term course may be offered: Summer
Grading: Offered for satisfactory/unsatisfactory grade only.
Hours and format: 6 hours of work per week per unit for 8 weeks. 8 hours of work per week per unit for 6 weeks.
Prerequisites: Graduate standing.
Investigations of advanced problems in bioengineering.
Course may be repeated for credit. Course may be repeated for credit when topic changes.
BIO ENG 301 Teaching Techniques for Bioengineering 1 Unit
Department: Bioengineering
Course level: Professional course for teachers or prospective teachers
Term course may be offered: Fall
Grading: Offered for satisfactory/unsatisfactory grade only.
Hours and format: 1 hour of Seminar per week for 15 weeks.
Prerequisites: Graduate standing.
Weekly seminars and discussions of effective teaching techniques. Use of educational objectives, alternative forms of instruction, and special techniques for teaching key concepts and techniques in bioengineering. Course is intended to orient new graduate student instructors to teaching in the Bioengineering department at Berkeley.
Course may be repeated for credit. Course may be repeated for credit when topic changes. Instructor: Johnson
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